An independent and comprehensive evaluation of the CAZyme classifiers: - dbCAN2 - dbCAN3 - dbCAN4 - eCAMI - CUPP - HMMER (dbCAN4) - dbCAN-sub (dbCAN4) - DIAMOND (dbCAN4)
Evaluating performance of: - Binary CAZyme/non-CAZyme classification - Test set dependent performance of CAZyme/non-CAZyme classification - Binary classification per CAZy class - Multilabel CAZy class classification - Binary classification per CAZy family - Multilabel CAZy family classification
The CAZyme classifier dbCAN is available as a webserver and a standalone tool. In this evaluation the standalone tool was used, and is referred to as dbCAN, references to the webserver are defined as the dbCAN webserver. The version numbers of the standalone tool and the webserver are independent of one another: * The dbCAN2 webserver initally ran dbCAN version 2 (referred to as dbCAN2) * The dbCAN2 webserver than implememented the standalone dbCAN version 3 (referred to as dbCAN3) * The dbCAN3 webserver implements the standalone dbCAN version 4 (referred to as dbCAN4)
Each version of dbCAN implements multiple sequence alignment and modelling tools: * dbCAN2: * DIAMOND * HMMER * Hotpep * dbCAN3: * DIAMOND * HMMER * eCAMI * dbCAN4: * DIAMOND * HMMER * dbCAN-sub (implementation of HMMER)
All references to implementing HMMER and DIAMOND refer to the implementation of these tools by dbCAN. For this evaluation, specifically the implementation of HMMER and DIAMOND by dbCAN4.
Han Zhang and others, dbCAN2: a meta server for automated carbohydrate-active enzyme annotation, Nucleic Acids Research, Volume 46, Issue W1, 2 July 2018, Pages W95–W101
Zheng J, Ge Q, Yan Y, Zhang X, Huang L, Yin Y. dbCAN3: automated carbohydrate-active enzyme and substrate annotation. Nucleic Acids Res. 2023 Jul 5;51(W1):W115-W121
Xu J, Zhang H, Zheng J, Dovoedo P, Yin Y. eCAMI: simultaneous classification and motif identification for enzyme annotation. Bioinformatics. 2020 Apr 1;36(7):2068-2075
Barrett, K., Lange, L. Peptide-based functional annotation of carbohydrate-active enzymes by conserved unique peptide patterns (CUPP). Biotechnol Biofuels 12, 102 (2019). https://doi.org/10.1186/s13068-019-1436-5
Eddy SR. Profile hidden Markov models. Bioinformatics. 1998;14(9):755-63.
Buchfink, B., Xie, C. & Huson, D. Fast and sensitive protein alignment using DIAMOND. Nat Methods 12, 59–60 (2015). https://doi.org/10.1038/nmeth.3176
CAZyme classifiers analyse query protein sequence and predict CAZyme domains and associated CAZy family annotations. This enables exploratory analysis of CAZyme complements not presently catalogued in the CAZy database (www.cazy.org). Each CAZyme classifier implements a different method to predict CAZy family annotations.
We previously published an evaluation of dbCAN2, eCAMI and CUPP (Hobbs et al., 2021). Since then, two standalone versions of dbCAN have been released (dbCAN3 and dbCAN4). Additionally, the previous analysis was limited to 70 genomes, over weighted towards bacterial genomes. To address these points, we present here an independent and comprehensive evaluation of the CAZyme classifiers: * dbCAN2 (v2.0.11) * dbCAN3 (v3.0.7) * dbCAN4 (v4.0.0) * eCAMI (implemented by dbCAN_3 (3.0.7)) * CUPP (v???) * HMMER (from dbCAN4) * dbCAN-sub (from dbCAN4) * DIAMOND (from dbCAN4)
Evaluating performance of: * Binary CAZyme/non-CAZyme classification * Test set dependent performance of CAZyme/non-CAZyme classification * Binary classification per CAZy class * Multilabel CAZy class classification * Binary classification per CAZy family * Multilabel CAZy family classification
Hobbs, Emma E. M.; Gloster, Tracey M.; Chapman, Sean; Pritchard, Leighton (2021). Microbiology Society Annual Conference 2021. figshare. Poster. https://doi.org/10.6084/m9.figshare.14370836.v3
A single test set of 100 CAZymes and 100 non-CAZymes with the highest sequence similarity (rated by bit-score ratio) was created per genomic assembly selected to be included in the benchmark test set.
Choosing the 100 non-CAZymes with the highest sequence similarity was devised to increase the probability of causing confusion, to gather a better idea of the expected performance when using the classifiers. An equal number of CAZymes to non-CAZymes was selected to prevent over representation of one population over the other.
For inclusion of a genomic assembly for the creation of a test set, the assembly had to meet of all the following criteria:
The genomic assemblies were also chosen from a range of taxonomies to provide as informative image of the performance of the classifiers over a range of datasets that users may wish to analyse.
We took the 70 test sets used in the previous evaluation (Hobbs et al., 2021), and added an additional 10 genomes.
## [1] "Mean percentage of genome incorporated in the CAZome across all test sets:"
## [1] 3.22
## [1] "Standard deviation of the percentage of genome incorporated in the CAZome across all test sets:"
## [1] 1.17
## [1] "Mean percentage of CAZomes incorporated in the test set across all genomes:"
## [1] 58.6
## [1] "Standard deviation of the percentage of CAZome incorporated in the test set across all genomes:"
## [1] 27.55
Figure 3.1: Histogram of CAZome coverage of the test sets for each respective source genomic assembly, overlayed by a box and whisker plot of the percentage of the CAZome incorproated in the test set.
The assignment of CAZy family annotations by a CAZyme classifier identifies the protein as a CAZyme. If no CAZy family annotations are assigned to a protein by a CAZyme classifier, the tool identified the protein as a non-CAZyme. Here we evaluate the performance of each CAZyme classifier to differentiate between CAZymes and non-CAZymes (defined as proteins catalogued and not catalogued in CAZy respectively).
For every classifier-test set pair, the specificity, sensitivity, prevision, F1-score and accuracy was calculated. The mean of each statistical parameter was calculated for each classifier across all tests, to represent the overall performance of each classifier. The 95% confidence interval (CI) was also calculated owing the tendancy of the mean to skew towards 1. These results are presented in table 4.1.
| Classifier | Spec Mean | Spec Standard Deviation | Spec Lower CI | Spec Upper CI | Sens Mean | Sens Standard Deviation | Sens Lower CI | Sens Upper CI | Prec Mean | Prec Standard Deviation | Prec Lower CI | Prec Upper CI | F1-score Mean | F1-score Standard Deviation | F1-score Lower CI | F1-score Upper CI | Acc Mean | Acc Standard Deviation | Acc Lower CI | Acc Upper CI |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CUPP | 0.9818 | 0.0487 | 0.9709 | 0.9926 | 0.8539 | 0.0744 | 0.8373 | 0.8704 | 0.9812 | 0.0454 | 0.9711 | 0.9913 | 0.9109 | 0.0520 | 0.8994 | 0.9225 | 0.9178 | 0.0460 | 0.9076 | 0.9280 |
| dbCAN_2 | 0.9772 | 0.0526 | 0.9655 | 0.9890 | 0.9012 | 0.1082 | 0.8772 | 0.9253 | 0.9779 | 0.0453 | 0.9679 | 0.9880 | 0.9332 | 0.0789 | 0.9157 | 0.9508 | 0.9392 | 0.0596 | 0.9260 | 0.9525 |
| dbCAN_2:DIAMOND | 0.9744 | 0.0542 | 0.9623 | 0.9864 | 0.9158 | 0.1287 | 0.8871 | 0.9444 | 0.9758 | 0.0448 | 0.9659 | 0.9858 | 0.9380 | 0.0923 | 0.9175 | 0.9586 | 0.9451 | 0.0673 | 0.9301 | 0.9600 |
| dbCAN_2:HMMER | 0.9786 | 0.0517 | 0.9671 | 0.9901 | 0.8779 | 0.0807 | 0.8599 | 0.8958 | 0.9788 | 0.0446 | 0.9689 | 0.9887 | 0.9225 | 0.0639 | 0.9083 | 0.9367 | 0.9282 | 0.0473 | 0.9177 | 0.9388 |
| dbCAN_2:Hotpep | 0.9759 | 0.0459 | 0.9657 | 0.9861 | 0.8084 | 0.1268 | 0.7801 | 0.8366 | 0.9717 | 0.0535 | 0.9598 | 0.9836 | 0.8771 | 0.0916 | 0.8567 | 0.8975 | 0.8921 | 0.0714 | 0.8762 | 0.9080 |
| dbCAN_3 | 0.9592 | 0.0768 | 0.9422 | 0.9763 | 0.9871 | 0.0436 | 0.9774 | 0.9968 | 0.9644 | 0.0556 | 0.9521 | 0.9768 | 0.9742 | 0.0410 | 0.9651 | 0.9833 | 0.9732 | 0.0436 | 0.9635 | 0.9829 |
| dbCAN_3:DIAMOND | 0.9665 | 0.0736 | 0.9501 | 0.9829 | 0.9689 | 0.0823 | 0.9506 | 0.9872 | 0.9706 | 0.0543 | 0.9586 | 0.9827 | 0.9664 | 0.0660 | 0.9517 | 0.9811 | 0.9677 | 0.0542 | 0.9556 | 0.9798 |
| dbCAN_3:eCAMI | 0.9752 | 0.0475 | 0.9647 | 0.9858 | 0.8516 | 0.1278 | 0.8232 | 0.8801 | 0.9738 | 0.0463 | 0.9635 | 0.9841 | 0.9026 | 0.0870 | 0.8832 | 0.9220 | 0.9134 | 0.0682 | 0.8983 | 0.9286 |
| dbCAN_3:HMMER | 0.9788 | 0.0520 | 0.9672 | 0.9903 | 0.8880 | 0.0818 | 0.8698 | 0.9062 | 0.9791 | 0.0448 | 0.9692 | 0.9891 | 0.9282 | 0.0646 | 0.9139 | 0.9426 | 0.9334 | 0.0481 | 0.9227 | 0.9441 |
| dbCAN_4 | 0.9622 | 0.0763 | 0.9453 | 0.9792 | 0.9841 | 0.0640 | 0.9699 | 0.9984 | 0.9672 | 0.0555 | 0.9549 | 0.9796 | 0.9733 | 0.0531 | 0.9614 | 0.9851 | 0.9732 | 0.0491 | 0.9623 | 0.9841 |
| dbCAN_4:dbCAN-sub | 0.9775 | 0.0529 | 0.9657 | 0.9893 | 0.9498 | 0.0729 | 0.9335 | 0.9660 | 0.9792 | 0.0432 | 0.9696 | 0.9888 | 0.9618 | 0.0563 | 0.9493 | 0.9744 | 0.9636 | 0.0449 | 0.9536 | 0.9736 |
| dbCAN_4:DIAMOND | 0.9668 | 0.0744 | 0.9502 | 0.9833 | 0.9694 | 0.0835 | 0.9508 | 0.9880 | 0.9710 | 0.0545 | 0.9589 | 0.9832 | 0.9666 | 0.0694 | 0.9511 | 0.9820 | 0.9681 | 0.0547 | 0.9559 | 0.9802 |
| dbCAN_4:HMMER | 0.9788 | 0.0520 | 0.9672 | 0.9903 | 0.8900 | 0.0819 | 0.8718 | 0.9082 | 0.9792 | 0.0447 | 0.9692 | 0.9891 | 0.9293 | 0.0648 | 0.9149 | 0.9438 | 0.9344 | 0.0483 | 0.9236 | 0.9451 |
The 95% CI was plotted as error bars around the mean CI (figure 4.1.
Figure 4.1: Summary statistics of CAZyme classifiers performances of binary CAZyme/non-CAZyme prediction. The mean plus and minus the 95% confidence interval.
Specificity is the proportion of known negatives (known non-CAZymes) which are correctly classified as negatives (non-CAZymes). Figure 4.2 is a graphical representation of the results calculated in table 4.1.
Figure 4.2: One-dimensional scatter plot of specificity scores of CAZyme and non-CAZyme predictions per test set, overlaying box plot of standard deviation.
Sensitivity (also known as recall) is the proportion of known positives (CAZymes) that are correctly identified as positives (CAZymes). Figure 4.3 graphically represents of the results calculated in table 4.1.
Figure 4.3: One-dimensional scatter plot of recall (sensitivity) scores of CAZyme and non-CAZyme predictions per test set, overlaying box plot of standard deviation.
Precision is the proportion of positive predictions by the classifiers that are correct. In this case, precision represents the fraction of CAZyme predictions by the classifiers that are correct, specifically the proportion of predicted CAZymes that are known CAZymes. Figure 4.4 is a visual representation of the results calculated in table 4.1.
Figure 4.4: One-dimensional scatter plot of precision scores of CAZyme and non-CAZyme predictions per test set, overlaying box plot of standard deviation.
The F1-score is a harmonic (or weighted) average of recall and precision and provides an idea of the overall performance of the tool, 0 being the lowest and 1 being the best performance. Figure 4.5 shows the F1-score from each test set, for each classifier.
Figure 4.5: Bar chart of specificity of CAZyme classifiers differentiation between CAZymes and non-CAZymes.
Accuarcy (calculated using (TP + TN) / (TP + TN + FP + FN) ) provides an idea of the overall performance of the classifiers as a measure of the degree to which their CAZyme/non-CAZyme predictions conforms to the correct result. Figure 4.6 is a plot of respective data from table 4.1.
Figure 4.6: Bar chart of specificity of CAZyme classifiers differentiation between CAZymes and non-CAZymes.
Here we generate a plot that combines the plots from above into a single figure.
Figure 4.7: Box and whisker plots of the performance of CAZyme/non-CAZyme classification.
The Receiver Operator Characteristic (ROC) curve (in figure 4.8) enables us to compare sensitivity to specificity but plotting sensitivity versus 1-specificity.
Figure 4.8: Receiver Operator Characteristic (ROC) curve of CAZyme/non-CAZyme classification.
bin.roc.df.main <- bin.roc.df[which(bin.roc.df$Prediction_tool %in% c('dbCAN_2','dbCAN_3','dbCAN_4','CUPP')), ]
p.roc.main <- ggplot(bin.roc.df.main, aes(x=Specificity, y=Sensitivity, color = Prediction_tool)) +
geom_line() +
geom_point(aes(shape=Prediction_tool)) +
scale_color_manual(values = colour_set_roc) +
xlab("1 - Specificity") +
ylab("Sensitivity")
p.roc.main
The statistics evaluated above provide an idea of the general performance of the tools, but they do not provide an idea of the expect range of performance. Specifically, the data does not provide a clear image of the best and worse performance a user can expect when using these tools.
To compare the expected typical range in accuracies for each classifier, 6 test sets (identified by the source genomic assemblies) were selected at random. The CAZyme/non-CAZyme predictions for each classifier, for each test set, were bootstrap resampled 100 times each, and for each bootstrap sample the accuracy calculated. The accuracies of the bootstrap samples for each classifier were plotted on stacked histograms, shown in figure 4.9.
Figure 4.9: Stacked histograms of bootstrap sample accuracies of CAZyme classifiers’ differentiation between CAZymes and non-CAZymes. 6 test sets (identified by their source genomic assembly) were selected at random. The CAZyme/non-CAZyme predictions for each classifier, for each test set, were bootstrap resampled 100 times. The accuracy of each of the 600 bootstrap samples per test set were plotted as a stacked histogram.
Overall, all tools showed a low probability of producing false positives (missclassifying a non-CAZyme as a CAZyme), and few of the positive predictions are false positives. Therefore, we can be confident in that the CAZyme predictions made by each of these tools are most likely correct. However, all the classifiers demonstrated a consistent behaviour to not identify all CAZymes within a CAZome. Therefore, we can be confident in the CAZyme predictions, but should not presume all non-CAZyme predictions are correct; these classifiers are unlikely to identify the complete CAZome although a near-complete CAZome will be accurately identified.
The performance for a classifier per taxonomy group may vary. For this evaluation the test sets were separated into the taxonomy groups: - Bacteria - Eukaryote
The evaluation per classifier per taxonomy group, versus all test sets pooled together was evaluated.
| Prediction_tool | Bact Mean | Bact Standard Deviation | Bact Lower CI | Bact Upper CI | Euk Mean | Euk Standard Deviation | Euk Lower CI | Euk Upper CI | All Mean | All Standard Deviation | All Lower CI | All Upper CI |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CUPP | 0.9888 | 0.0276 | 0.9799 | 0.9976 | 0.9748 | 0.0628 | 0.9547 | 0.9948 | 0.9818 | 0.0486 | 0.9742 | 0.9893 |
| dbCAN_2 | 0.9828 | 0.0349 | 0.9716 | 0.9939 | 0.9718 | 0.0658 | 0.9507 | 0.9928 | 0.9772 | 0.0525 | 0.9691 | 0.9854 |
| dbCAN_2:DIAMOND | 0.9790 | 0.0352 | 0.9677 | 0.9903 | 0.9698 | 0.0684 | 0.9479 | 0.9916 | 0.9744 | 0.0541 | 0.9659 | 0.9828 |
| dbCAN_2:HMMER | 0.9858 | 0.0286 | 0.9766 | 0.9949 | 0.9715 | 0.0670 | 0.9501 | 0.9929 | 0.9786 | 0.0515 | 0.9706 | 0.9867 |
| dbCAN_2:Hotpep | 0.9788 | 0.0344 | 0.9677 | 0.9898 | 0.9730 | 0.0553 | 0.9553 | 0.9907 | 0.9759 | 0.0457 | 0.9687 | 0.9830 |
| dbCAN_3 | 0.9685 | 0.0402 | 0.9557 | 0.9813 | 0.9500 | 0.1007 | 0.9178 | 0.9822 | 0.9592 | 0.0765 | 0.9473 | 0.9712 |
| dbCAN_3:DIAMOND | 0.9785 | 0.0363 | 0.9669 | 0.9901 | 0.9545 | 0.0967 | 0.9236 | 0.9854 | 0.9665 | 0.0734 | 0.9550 | 0.9780 |
| dbCAN_3:HMMER | 0.9868 | 0.0284 | 0.9777 | 0.9958 | 0.9708 | 0.0673 | 0.9492 | 0.9923 | 0.9788 | 0.0518 | 0.9707 | 0.9868 |
| dbCAN_3:eCAMI | 0.9772 | 0.0351 | 0.9660 | 0.9885 | 0.9732 | 0.0578 | 0.9548 | 0.9917 | 0.9752 | 0.0474 | 0.9678 | 0.9827 |
| dbCAN_4 | 0.9740 | 0.0383 | 0.9618 | 0.9862 | 0.9505 | 0.1003 | 0.9184 | 0.9826 | 0.9622 | 0.0761 | 0.9504 | 0.9741 |
| dbCAN_4:DIAMOND | 0.9798 | 0.0355 | 0.9684 | 0.9911 | 0.9538 | 0.0980 | 0.9224 | 0.9851 | 0.9668 | 0.0742 | 0.9552 | 0.9783 |
| dbCAN_4:HMMER | 0.9868 | 0.0284 | 0.9777 | 0.9958 | 0.9708 | 0.0673 | 0.9492 | 0.9923 | 0.9788 | 0.0518 | 0.9707 | 0.9868 |
| dbCAN_4:dbCAN-sub | 0.9868 | 0.0270 | 0.9781 | 0.9954 | 0.9682 | 0.0690 | 0.9462 | 0.9903 | 0.9775 | 0.0527 | 0.9693 | 0.9857 |
pdf(file = "../report/cazyme_noncazyme_classification/tax_performance/specificity.ci.pdf", width = 6.23, height = 8.2)
p.bin.spec.tax.ci
dev.off()
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pdf(file = "../report/cazyme_noncazyme_classification/tax_performance/specificity.scatter.pdf", width = 6.23, height = 8.2)
p.bin.spec.tax.scatter
dev.off()
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| Prediction_tool | Bact Mean | Bact Standard Deviation | Bact Lower CI | Bact Upper CI | Euk Mean | Euk Standard Deviation | Euk Lower CI | Euk Upper CI | All Mean | All Standard Deviation | All Lower CI | All Upper CI |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CUPP | 0.8618 | 0.0788 | 0.8366 | 0.8869 | 0.8460 | 0.0699 | 0.8236 | 0.8684 | 0.8539 | 0.0742 | 0.8423 | 0.8655 |
| dbCAN_2 | 0.9052 | 0.1144 | 0.8686 | 0.9419 | 0.8972 | 0.1029 | 0.8643 | 0.9302 | 0.9012 | 0.1079 | 0.8844 | 0.9181 |
| dbCAN_2:DIAMOND | 0.9182 | 0.1346 | 0.8752 | 0.9613 | 0.9132 | 0.1241 | 0.8736 | 0.9529 | 0.9158 | 0.1283 | 0.8957 | 0.9358 |
| dbCAN_2:HMMER | 0.8695 | 0.1078 | 0.8350 | 0.9040 | 0.8862 | 0.0379 | 0.8741 | 0.8984 | 0.8779 | 0.0804 | 0.8653 | 0.8904 |
| dbCAN_2:Hotpep | 0.8195 | 0.1164 | 0.7823 | 0.8567 | 0.7972 | 0.1371 | 0.7534 | 0.8411 | 0.8084 | 0.1264 | 0.7886 | 0.8281 |
| dbCAN_3 | 0.9832 | 0.0605 | 0.9639 | 1.0026 | 0.9910 | 0.0130 | 0.9869 | 0.9951 | 0.9871 | 0.0435 | 0.9803 | 0.9939 |
| dbCAN_3:DIAMOND | 0.9560 | 0.1088 | 0.9212 | 0.9908 | 0.9818 | 0.0392 | 0.9692 | 0.9943 | 0.9689 | 0.0820 | 0.9561 | 0.9817 |
| dbCAN_3:HMMER | 0.8728 | 0.1088 | 0.8380 | 0.9075 | 0.9032 | 0.0353 | 0.8920 | 0.9145 | 0.8880 | 0.0815 | 0.8753 | 0.9007 |
| dbCAN_3:eCAMI | 0.8832 | 0.1258 | 0.8430 | 0.9235 | 0.8200 | 0.1232 | 0.7806 | 0.8594 | 0.8516 | 0.1273 | 0.8317 | 0.8715 |
| dbCAN_4 | 0.9748 | 0.0897 | 0.9461 | 1.0034 | 0.9935 | 0.0083 | 0.9908 | 0.9962 | 0.9841 | 0.0638 | 0.9742 | 0.9941 |
| dbCAN_4:DIAMOND | 0.9498 | 0.1149 | 0.9130 | 0.9865 | 0.9890 | 0.0110 | 0.9855 | 0.9925 | 0.9694 | 0.0832 | 0.9564 | 0.9824 |
| dbCAN_4:HMMER | 0.8765 | 0.1097 | 0.8414 | 0.9116 | 0.9035 | 0.0342 | 0.8926 | 0.9144 | 0.8900 | 0.0816 | 0.8773 | 0.9027 |
| dbCAN_4:dbCAN-sub | 0.9520 | 0.1011 | 0.9197 | 0.9843 | 0.9475 | 0.0228 | 0.9402 | 0.9548 | 0.9498 | 0.0726 | 0.9384 | 0.9611 |
pdf(file = "../report/cazyme_noncazyme_classification/tax_performance/sensitivity.ci.pdf", width = 6.23, height = 8.2)
p.bin.sens.tax.ci
dev.off()
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pdf(file = "../report/cazyme_noncazyme_classification/tax_performance/sensitivity.scatter.pdf", width = 6.23, height = 8.2)
p.bin.sens.tax.scatter
dev.off()
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| Prediction_tool | Bact Mean | Bact Standard Deviation | Bact Lower CI | Bact Upper CI | Euk Mean | Euk Standard Deviation | Euk Lower CI | Euk Upper CI | All Mean | All Standard Deviation | All Lower CI | All Upper CI |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CUPP | 0.9877 | 0.0280 | 0.9787 | 0.9966 | 0.9748 | 0.0574 | 0.9564 | 0.9932 | 0.9812 | 0.0452 | 0.9742 | 0.9883 |
| dbCAN_2 | 0.9824 | 0.0348 | 0.9713 | 0.9936 | 0.9734 | 0.0540 | 0.9562 | 0.9907 | 0.9779 | 0.0452 | 0.9709 | 0.9850 |
| dbCAN_2:DIAMOND | 0.9791 | 0.0348 | 0.9680 | 0.9902 | 0.9726 | 0.0533 | 0.9555 | 0.9896 | 0.9758 | 0.0447 | 0.9689 | 0.9828 |
| dbCAN_2:HMMER | 0.9847 | 0.0299 | 0.9751 | 0.9943 | 0.9729 | 0.0553 | 0.9552 | 0.9906 | 0.9788 | 0.0445 | 0.9719 | 0.9857 |
| dbCAN_2:Hotpep | 0.9759 | 0.0381 | 0.9637 | 0.9881 | 0.9676 | 0.0656 | 0.9466 | 0.9885 | 0.9717 | 0.0533 | 0.9634 | 0.9801 |
| dbCAN_3 | 0.9704 | 0.0357 | 0.9590 | 0.9818 | 0.9585 | 0.0702 | 0.9361 | 0.9810 | 0.9644 | 0.0555 | 0.9558 | 0.9731 |
| dbCAN_3:DIAMOND | 0.9795 | 0.0332 | 0.9689 | 0.9901 | 0.9618 | 0.0686 | 0.9399 | 0.9837 | 0.9706 | 0.0541 | 0.9622 | 0.9791 |
| dbCAN_3:HMMER | 0.9858 | 0.0297 | 0.9763 | 0.9953 | 0.9725 | 0.0556 | 0.9547 | 0.9903 | 0.9791 | 0.0446 | 0.9722 | 0.9861 |
| dbCAN_3:eCAMI | 0.9764 | 0.0349 | 0.9653 | 0.9876 | 0.9713 | 0.0557 | 0.9534 | 0.9891 | 0.9738 | 0.0461 | 0.9666 | 0.9810 |
| dbCAN_4 | 0.9755 | 0.0346 | 0.9645 | 0.9866 | 0.9589 | 0.0700 | 0.9365 | 0.9813 | 0.9672 | 0.0553 | 0.9586 | 0.9759 |
| dbCAN_4:DIAMOND | 0.9805 | 0.0327 | 0.9701 | 0.9910 | 0.9615 | 0.0690 | 0.9394 | 0.9836 | 0.9710 | 0.0544 | 0.9625 | 0.9795 |
| dbCAN_4:HMMER | 0.9858 | 0.0297 | 0.9763 | 0.9953 | 0.9725 | 0.0556 | 0.9548 | 0.9903 | 0.9792 | 0.0446 | 0.9722 | 0.9861 |
| dbCAN_4:dbCAN-sub | 0.9869 | 0.0258 | 0.9786 | 0.9951 | 0.9715 | 0.0547 | 0.9540 | 0.9889 | 0.9792 | 0.0431 | 0.9724 | 0.9859 |
pdf(file = "../report/cazyme_noncazyme_classification/tax_performance/precision.ci.pdf", width = 6.23, height = 8.2)
p.bin.prec.tax.ci
dev.off()
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pdf(file = "../report/cazyme_noncazyme_classification/tax_performance/precision.scatter.pdf", width = 6.23, height = 8.2)
p.bin.prec.tax.scatter
dev.off()
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| Prediction_tool | Bact Mean | Bact Standard Deviation | Bact Lower CI | Bact Upper CI | Euk Mean | Euk Standard Deviation | Euk Lower CI | Euk Upper CI | All Mean | All Standard Deviation | All Lower CI | All Upper CI |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CUPP | 0.9184 | 0.0518 | 0.9018 | 0.9349 | 0.9035 | 0.0519 | 0.8869 | 0.9201 | 0.9109 | 0.0519 | 0.9028 | 0.9190 |
| dbCAN_2 | 0.9373 | 0.0837 | 0.9105 | 0.9640 | 0.9292 | 0.0746 | 0.9053 | 0.9530 | 0.9332 | 0.0786 | 0.9209 | 0.9455 |
| dbCAN_2:DIAMOND | 0.9406 | 0.0985 | 0.9091 | 0.9722 | 0.9354 | 0.0868 | 0.9076 | 0.9632 | 0.9380 | 0.0920 | 0.9237 | 0.9524 |
| dbCAN_2:HMMER | 0.9188 | 0.0839 | 0.8919 | 0.9456 | 0.9263 | 0.0346 | 0.9152 | 0.9373 | 0.9225 | 0.0637 | 0.9126 | 0.9324 |
| dbCAN_2:Hotpep | 0.8861 | 0.0757 | 0.8619 | 0.9103 | 0.8680 | 0.1053 | 0.8344 | 0.9017 | 0.8771 | 0.0913 | 0.8628 | 0.8913 |
| dbCAN_3 | 0.9753 | 0.0406 | 0.9623 | 0.9883 | 0.9730 | 0.0418 | 0.9596 | 0.9864 | 0.9742 | 0.0408 | 0.9678 | 0.9805 |
| dbCAN_3:DIAMOND | 0.9628 | 0.0818 | 0.9366 | 0.9889 | 0.9700 | 0.0459 | 0.9553 | 0.9847 | 0.9664 | 0.0658 | 0.9561 | 0.9767 |
| dbCAN_3:HMMER | 0.9210 | 0.0845 | 0.8940 | 0.9481 | 0.9354 | 0.0347 | 0.9243 | 0.9465 | 0.9282 | 0.0644 | 0.9182 | 0.9383 |
| dbCAN_3:eCAMI | 0.9219 | 0.0802 | 0.8962 | 0.9476 | 0.8833 | 0.0903 | 0.8544 | 0.9121 | 0.9026 | 0.0868 | 0.8890 | 0.9161 |
| dbCAN_4 | 0.9720 | 0.0627 | 0.9519 | 0.9920 | 0.9745 | 0.0421 | 0.9611 | 0.9880 | 0.9733 | 0.0529 | 0.9650 | 0.9815 |
| dbCAN_4:DIAMOND | 0.9594 | 0.0890 | 0.9310 | 0.9879 | 0.9737 | 0.0415 | 0.9604 | 0.9870 | 0.9666 | 0.0691 | 0.9558 | 0.9774 |
| dbCAN_4:HMMER | 0.9231 | 0.0851 | 0.8959 | 0.9503 | 0.9356 | 0.0343 | 0.9246 | 0.9465 | 0.9293 | 0.0646 | 0.9193 | 0.9394 |
| dbCAN_4:dbCAN-sub | 0.9654 | 0.0738 | 0.9418 | 0.9889 | 0.9583 | 0.0308 | 0.9484 | 0.9682 | 0.9618 | 0.0561 | 0.9531 | 0.9706 |
pdf(file = "../report/cazyme_noncazyme_classification/tax_performance/F1-score.ci.pdf", width = 6.23, height = 8.2)
p.bin.f1.tax.ci
dev.off()
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pdf(file = "../report/cazyme_noncazyme_classification/tax_performance/F1-score.scatter.pdf", width = 6.23, height = 8.2)
p.bin.f1.tax.scatter
dev.off()
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| Prediction_tool | Bact Mean | Bact Standard Deviation | Bact Lower CI | Bact Upper CI | Euk Mean | Euk Standard Deviation | Euk Lower CI | Euk Upper CI | All Mean | All Standard Deviation | All Lower CI | All Upper CI |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CUPP | 0.9252 | 0.0430 | 0.9115 | 0.9390 | 0.9104 | 0.0481 | 0.8950 | 0.9258 | 0.9178 | 0.0458 | 0.9107 | 0.9250 |
| dbCAN_2 | 0.9440 | 0.0600 | 0.9248 | 0.9632 | 0.9345 | 0.0594 | 0.9155 | 0.9535 | 0.9392 | 0.0594 | 0.9300 | 0.9485 |
| dbCAN_2:DIAMOND | 0.9486 | 0.0687 | 0.9267 | 0.9706 | 0.9415 | 0.0666 | 0.9202 | 0.9628 | 0.9451 | 0.0671 | 0.9346 | 0.9555 |
| dbCAN_2:HMMER | 0.9276 | 0.0561 | 0.9097 | 0.9456 | 0.9289 | 0.0372 | 0.9170 | 0.9408 | 0.9282 | 0.0472 | 0.9209 | 0.9356 |
| dbCAN_2:Hotpep | 0.8991 | 0.0603 | 0.8799 | 0.9184 | 0.8851 | 0.0813 | 0.8591 | 0.9111 | 0.8921 | 0.0712 | 0.8810 | 0.9032 |
| dbCAN_3 | 0.9759 | 0.0354 | 0.9645 | 0.9872 | 0.9705 | 0.0509 | 0.9542 | 0.9868 | 0.9732 | 0.0435 | 0.9664 | 0.9800 |
| dbCAN_3:DIAMOND | 0.9672 | 0.0561 | 0.9493 | 0.9852 | 0.9681 | 0.0531 | 0.9512 | 0.9851 | 0.9677 | 0.0541 | 0.9592 | 0.9761 |
| dbCAN_3:HMMER | 0.9298 | 0.0568 | 0.9116 | 0.9479 | 0.9370 | 0.0378 | 0.9249 | 0.9491 | 0.9334 | 0.0479 | 0.9259 | 0.9409 |
| dbCAN_3:eCAMI | 0.9302 | 0.0635 | 0.9099 | 0.9506 | 0.8966 | 0.0693 | 0.8745 | 0.9188 | 0.9134 | 0.0680 | 0.9028 | 0.9241 |
| dbCAN_4 | 0.9744 | 0.0474 | 0.9592 | 0.9895 | 0.9720 | 0.0513 | 0.9556 | 0.9884 | 0.9732 | 0.0489 | 0.9655 | 0.9808 |
| dbCAN_4:DIAMOND | 0.9648 | 0.0591 | 0.9459 | 0.9836 | 0.9714 | 0.0504 | 0.9552 | 0.9875 | 0.9681 | 0.0545 | 0.9596 | 0.9766 |
| dbCAN_4:HMMER | 0.9316 | 0.0574 | 0.9133 | 0.9500 | 0.9371 | 0.0375 | 0.9251 | 0.9491 | 0.9344 | 0.0481 | 0.9269 | 0.9419 |
| dbCAN_4:dbCAN-sub | 0.9694 | 0.0528 | 0.9525 | 0.9863 | 0.9579 | 0.0351 | 0.9466 | 0.9691 | 0.9636 | 0.0448 | 0.9566 | 0.9706 |
pdf(file = "../report/cazyme_noncazyme_classification/tax_performance/accuracy.ci.pdf", width = 6.23, height = 8.2)
p.bin.acc.tax.ci
dev.off()
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## 2
pdf(file = "../report/cazyme_noncazyme_classification/tax_performance/accuracy.scatter.pdf", width = 6.23, height = 8.2)
p.bin.acc.tax.scatter
dev.off()
## png
## 2
CAZy groups CAZymes into CAZy families by sequence similarity, and CAZy families are grouped into one of 6 functional classes. The CAZyme classifiers predict the CAZy family annotations of predicted CAZymes, but it is of interest to see what the level of performance of the classiferis is at the CAZy class level. Specifically, a classifier may struggle to predict the correct CAZy class for a CAZyme but consistently predict the correct CAZy class. Therefore, the aim of this part of the evaluation is to evaluate the performance of the classifiers to predict the correct CAZy class of predict CAZymes.
Below is a table summary all statistical parameters calculated in order to evaluate the performance of the CAZy class classification for each prediction tool across all CAZy classes.
| Classifier | Spec Mean | Spec Standard Deviation | Spec Lower CI | Spec Upper CI | Sens Mean | Sens Standard Deviation | Sens Lower CI | Sens Upper CI | Prec Mean | Prec Standard Deviation | Prec Lower CI | Prec Upper CI | F1-score Mean | F1-score Standard Deviation | F1-score Lower CI | F1-score Upper CI | Acc Mean | Acc Standard Deviation | Acc Lower CI | Acc Upper CI |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CUPP | 0.9953 | 0.0246 | 0.9929 | 0.9977 | 0.7144 | 0.3745 | 0.6781 | 0.7507 | 0.7785 | 0.3984 | 0.7399 | 0.8172 | 0.7389 | 0.3799 | 0.7021 | 0.7757 | 0.9538 | 0.0617 | 0.9479 | 0.9598 |
| dbCAN_2 | 0.9933 | 0.0259 | 0.9908 | 0.9958 | 0.8735 | 0.1733 | 0.8567 | 0.8903 | 0.9568 | 0.1292 | 0.9442 | 0.9693 | 0.9025 | 0.1440 | 0.8886 | 0.9165 | 0.9738 | 0.0433 | 0.9696 | 0.9780 |
| dbCAN_2:DIAMOND | 0.9920 | 0.0270 | 0.9894 | 0.9946 | 0.8733 | 0.2042 | 0.8535 | 0.8931 | 0.9486 | 0.1566 | 0.9335 | 0.9638 | 0.8961 | 0.1758 | 0.8791 | 0.9132 | 0.9762 | 0.0451 | 0.9719 | 0.9806 |
| dbCAN_2:HMMER | 0.9939 | 0.0264 | 0.9913 | 0.9964 | 0.8074 | 0.2458 | 0.7836 | 0.8313 | 0.9544 | 0.1428 | 0.9406 | 0.9683 | 0.8513 | 0.2041 | 0.8315 | 0.8711 | 0.9652 | 0.0410 | 0.9612 | 0.9691 |
| dbCAN_2:Hotpep | 0.9733 | 0.0491 | 0.9685 | 0.9781 | 0.8023 | 0.2049 | 0.7825 | 0.8222 | 0.8559 | 0.2436 | 0.8323 | 0.8796 | 0.8057 | 0.2061 | 0.7857 | 0.8257 | 0.9384 | 0.0681 | 0.9318 | 0.9450 |
| dbCAN_3 | 0.9934 | 0.0265 | 0.9909 | 0.9960 | 0.9186 | 0.1454 | 0.9045 | 0.9327 | 0.9653 | 0.1101 | 0.9547 | 0.9760 | 0.9319 | 0.1204 | 0.9202 | 0.9436 | 0.9820 | 0.0340 | 0.9787 | 0.9852 |
| dbCAN_3:DIAMOND | 0.9909 | 0.0289 | 0.9881 | 0.9937 | 0.9495 | 0.1276 | 0.9372 | 0.9619 | 0.9584 | 0.1250 | 0.9463 | 0.9705 | 0.9459 | 0.1171 | 0.9346 | 0.9573 | 0.9864 | 0.0321 | 0.9833 | 0.9895 |
| dbCAN_3:eCAMI | 0.9829 | 0.0388 | 0.9791 | 0.9867 | 0.8106 | 0.2145 | 0.7899 | 0.8314 | 0.8880 | 0.2179 | 0.8669 | 0.9091 | 0.8323 | 0.2023 | 0.8127 | 0.8519 | 0.9553 | 0.0564 | 0.9498 | 0.9607 |
| dbCAN_3:HMMER | 0.9941 | 0.0261 | 0.9916 | 0.9967 | 0.8254 | 0.2443 | 0.8017 | 0.8491 | 0.9572 | 0.1355 | 0.9441 | 0.9704 | 0.8628 | 0.2004 | 0.8434 | 0.8823 | 0.9674 | 0.0411 | 0.9635 | 0.9714 |
| dbCAN_4 | 0.9936 | 0.0267 | 0.9910 | 0.9962 | 0.9353 | 0.1289 | 0.9228 | 0.9478 | 0.9684 | 0.0939 | 0.9593 | 0.9775 | 0.9431 | 0.1040 | 0.9330 | 0.9532 | 0.9838 | 0.0328 | 0.9807 | 0.9870 |
| dbCAN_4:dbCAN-sub | 0.9931 | 0.0269 | 0.9905 | 0.9957 | 0.9369 | 0.1257 | 0.9247 | 0.9491 | 0.9643 | 0.1001 | 0.9546 | 0.9740 | 0.9424 | 0.1048 | 0.9322 | 0.9526 | 0.9833 | 0.0315 | 0.9802 | 0.9863 |
| dbCAN_4:DIAMOND | 0.9915 | 0.0285 | 0.9888 | 0.9943 | 0.9580 | 0.1108 | 0.9472 | 0.9687 | 0.9633 | 0.1152 | 0.9521 | 0.9745 | 0.9532 | 0.1047 | 0.9431 | 0.9634 | 0.9871 | 0.0324 | 0.9839 | 0.9902 |
| dbCAN_4:HMMER | 0.9941 | 0.0262 | 0.9915 | 0.9966 | 0.8428 | 0.2281 | 0.8207 | 0.8650 | 0.9616 | 0.1240 | 0.9495 | 0.9736 | 0.8766 | 0.1860 | 0.8586 | 0.8947 | 0.9689 | 0.0404 | 0.9650 | 0.9729 |
Here we plot the 95% confidence intervals for CAZy class classification, when pooling all CAZy classes and test sets.
Figure 6.1: Summary statistics of CAZyme classifiers performances of CAZy class classification, plotting the mean plus and minus the 95% confidence interval.
Figure 6.2: Summary statistics of CAZyme classifiers performances of CAZy class classification, plotting statistical patermate value per test set for binary CAZy class classification across all CAZy classes.
Below is a proportional area plot representing the F1-score for each CAZyme classifier for each test set. Each square is sized proportional to the relative sample size. Every class was not included in every sample, resulting in different sample sizes between CAZy classes.
Figure 6.3: Proportional area plot of CAZy class classification performance. Performance is represented by the F1-score. Plots are proptional to the number of test sets, after excluding true negative classifications.
A dataframe of the number of test sets containing each CAZy class is generated (table 6.2).
| Prediction_tool | GH | GT | PL | CE | AA | CBM |
|---|---|---|---|---|---|---|
| dbCAN_2 | 80 | 80 | 47 | 76 | 48 | 80 |
| dbCAN_2:HMMER | 80 | 80 | 47 | 76 | 48 | 80 |
| dbCAN_2:DIAMOND | 80 | 80 | 47 | 76 | 48 | 80 |
| dbCAN_2:Hotpep | 80 | 80 | 47 | 76 | 48 | 80 |
| dbCAN_3 | 80 | 80 | 47 | 76 | 48 | 80 |
| dbCAN_3:HMMER | 80 | 80 | 47 | 76 | 48 | 80 |
| dbCAN_3:DIAMOND | 80 | 80 | 47 | 76 | 48 | 80 |
| dbCAN_3:eCAMI | 80 | 80 | 48 | 76 | 48 | 80 |
| dbCAN_4 | 80 | 80 | 47 | 76 | 48 | 80 |
| dbCAN_4:HMMER | 80 | 80 | 47 | 76 | 48 | 80 |
| dbCAN_4:DIAMOND | 80 | 80 | 47 | 76 | 48 | 80 |
| dbCAN_4:dbCAN-sub | 80 | 80 | 47 | 76 | 48 | 80 |
| CUPP | 80 | 80 | 47 | 76 | 48 | 80 |
The sensitivity of each CAZyme classifier can be plotted against the specificity for each CAZy class, however plotting all CAZy classes in a single plot produces a cramped plot, unless very few test sets were used.
Figure 6.4: Scatter plot of sensitivity against specificity for predicting CAZy class members per CAZyme classier
Below the prediction sensitivity is plotted against the specificity for each classifier, and a separate plot is generated for each CAZy class.
The scatter plots of sensitivity against specificity overlay a coloured contour to highlight the distribution of the points. When too many points have the same value a contour cannot be generated. In order to plot a contour noise is added to the data. The original data is used to plot the scatter plot and the data with added noise is used to plot the contour.
The percentage of the data points which need noise to be added to them in order to generate a contour varies from data set to data set. To change the percentage of the data points with noise added to them, change the third value of call to the function plot.class.sens.vs.spec(), which is used to generate the plots. The third value is the percentage of data points to add noise to, written in decimal form.
| Prediction_tool | Spec Mean | Spec Standard Deviation | Spec CI Lower | Spec CI Upper | Sens Mean | Sens Standard Deviation | Sens CI Lower | Sens CI Upper | Prec Mean | Prec Standard Deviation | Prec CI Lower | Prec CI Upper | F1-score Mean | F1-score Standard Deviation | F1-score CI Lower | F1-score CI Upper | Acc Mean | Acc Standard Deviation | Acc CI Lower | Acc CI Upper |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CUPP | 0.9933 | 0.0212 | 0.9886 | 0.9980 | 0.9080 | 0.0675 | 0.8930 | 0.9230 | 0.9906 | 0.0338 | 0.9831 | 0.9981 | 0.9461 | 0.0454 | 0.9360 | 0.9562 | 0.9540 | 0.0293 | 0.9475 | 0.9605 |
| dbCAN_2 | 0.9917 | 0.0245 | 0.9862 | 0.9972 | 0.9354 | 0.0907 | 0.9152 | 0.9556 | 0.9886 | 0.0347 | 0.9809 | 0.9963 | 0.9583 | 0.0614 | 0.9446 | 0.9719 | 0.9658 | 0.0361 | 0.9578 | 0.9738 |
| dbCAN_2:DIAMOND | 0.9862 | 0.0276 | 0.9801 | 0.9924 | 0.9379 | 0.1064 | 0.9142 | 0.9615 | 0.9845 | 0.0360 | 0.9765 | 0.9926 | 0.9563 | 0.0727 | 0.9401 | 0.9725 | 0.9644 | 0.0415 | 0.9551 | 0.9736 |
| dbCAN_2:HMMER | 0.9927 | 0.0242 | 0.9873 | 0.9981 | 0.9080 | 0.0824 | 0.8896 | 0.9263 | 0.9897 | 0.0339 | 0.9821 | 0.9972 | 0.9444 | 0.0587 | 0.9313 | 0.9574 | 0.9536 | 0.0330 | 0.9463 | 0.9609 |
| dbCAN_2:Hotpep | 0.9833 | 0.0286 | 0.9769 | 0.9897 | 0.8641 | 0.1181 | 0.8378 | 0.8904 | 0.9796 | 0.0419 | 0.9702 | 0.9889 | 0.9136 | 0.0773 | 0.8964 | 0.9308 | 0.9297 | 0.0495 | 0.9187 | 0.9407 |
| dbCAN_3 | 0.9923 | 0.0228 | 0.9873 | 0.9974 | 0.9567 | 0.0771 | 0.9396 | 0.9739 | 0.9897 | 0.0332 | 0.9823 | 0.9971 | 0.9708 | 0.0558 | 0.9583 | 0.9832 | 0.9768 | 0.0304 | 0.9701 | 0.9836 |
| dbCAN_3:DIAMOND | 0.9844 | 0.0292 | 0.9779 | 0.9909 | 0.9760 | 0.0673 | 0.9610 | 0.9910 | 0.9830 | 0.0391 | 0.9743 | 0.9917 | 0.9776 | 0.0491 | 0.9666 | 0.9885 | 0.9812 | 0.0295 | 0.9747 | 0.9878 |
| dbCAN_3:eCAMI | 0.9848 | 0.0295 | 0.9782 | 0.9913 | 0.8764 | 0.1097 | 0.8520 | 0.9008 | 0.9829 | 0.0395 | 0.9741 | 0.9917 | 0.9223 | 0.0695 | 0.9069 | 0.9378 | 0.9364 | 0.0485 | 0.9256 | 0.9472 |
| dbCAN_3:HMMER | 0.9939 | 0.0224 | 0.9889 | 0.9988 | 0.9198 | 0.0830 | 0.9013 | 0.9383 | 0.9909 | 0.0330 | 0.9836 | 0.9983 | 0.9514 | 0.0596 | 0.9382 | 0.9647 | 0.9599 | 0.0331 | 0.9525 | 0.9672 |
| dbCAN_4 | 0.9927 | 0.0240 | 0.9873 | 0.9980 | 0.9500 | 0.0802 | 0.9322 | 0.9679 | 0.9898 | 0.0337 | 0.9823 | 0.9973 | 0.9671 | 0.0590 | 0.9539 | 0.9802 | 0.9743 | 0.0307 | 0.9675 | 0.9812 |
| dbCAN_4:dbCAN-sub | 0.9924 | 0.0238 | 0.9871 | 0.9977 | 0.9473 | 0.0789 | 0.9297 | 0.9648 | 0.9896 | 0.0337 | 0.9821 | 0.9971 | 0.9655 | 0.0581 | 0.9526 | 0.9785 | 0.9731 | 0.0297 | 0.9665 | 0.9797 |
| dbCAN_4:DIAMOND | 0.9864 | 0.0279 | 0.9802 | 0.9927 | 0.9737 | 0.0763 | 0.9567 | 0.9906 | 0.9842 | 0.0393 | 0.9754 | 0.9929 | 0.9764 | 0.0583 | 0.9634 | 0.9894 | 0.9812 | 0.0304 | 0.9745 | 0.9880 |
| dbCAN_4:HMMER | 0.9939 | 0.0224 | 0.9889 | 0.9988 | 0.9202 | 0.0828 | 0.9017 | 0.9386 | 0.9909 | 0.0330 | 0.9836 | 0.9983 | 0.9516 | 0.0596 | 0.9384 | 0.9649 | 0.9601 | 0.0328 | 0.9528 | 0.9674 |
Figure 6.5: Scatter plot of sensitivity against specificity for predicting GH CAZy class members per CAZyme classier, overlaying a density map.
Figure 6.6: Summary statistics of CAZyme classifiers performances of GH class classification, plotting the mean plus and minus the 95% confidence interval.
Figure 6.7: One dimensional scatter plot of the statistical parameters per test set for the classification of GH class members, overlaying a box plot
| Prediction_tool | Spec Mean | Spec Standard Deviation | Spec CI Lower | Spec CI Upper | Sens Mean | Sens Standard Deviation | Sens CI Lower | Sens CI Upper | Prec Mean | Prec Standard Deviation | Prec CI Lower | Prec CI Upper | F1-score Mean | F1-score Standard Deviation | F1-score CI Lower | F1-score CI Upper | Acc Mean | Acc Standard Deviation | Acc CI Lower | Acc CI Upper |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CUPP | 0.9921 | 0.0463 | 0.9818 | 1.0024 | 0.8536 | 0.1107 | 0.8289 | 0.8782 | 0.9883 | 0.0625 | 0.9744 | 1.0022 | 0.9107 | 0.0758 | 0.8938 | 0.9276 | 0.9462 | 0.0579 | 0.9333 | 0.9591 |
| dbCAN_2 | 0.9927 | 0.0454 | 0.9826 | 1.0028 | 0.8845 | 0.1378 | 0.8538 | 0.9152 | 0.9898 | 0.0542 | 0.9778 | 1.0019 | 0.9258 | 0.1016 | 0.9032 | 0.9484 | 0.9550 | 0.0770 | 0.9379 | 0.9721 |
| dbCAN_2:DIAMOND | 0.9919 | 0.0460 | 0.9817 | 1.0021 | 0.9255 | 0.1508 | 0.8919 | 0.9591 | 0.9886 | 0.0567 | 0.9760 | 1.0013 | 0.9463 | 0.1124 | 0.9213 | 0.9713 | 0.9672 | 0.0821 | 0.9489 | 0.9854 |
| dbCAN_2:HMMER | 0.9904 | 0.0487 | 0.9796 | 1.0012 | 0.8627 | 0.1126 | 0.8376 | 0.8877 | 0.9884 | 0.0566 | 0.9758 | 1.0010 | 0.9152 | 0.0845 | 0.8964 | 0.9340 | 0.9498 | 0.0598 | 0.9365 | 0.9631 |
| dbCAN_2:Hotpep | 0.9924 | 0.0421 | 0.9830 | 1.0017 | 0.7254 | 0.1807 | 0.6852 | 0.7656 | 0.9836 | 0.0688 | 0.9683 | 0.9989 | 0.8209 | 0.1383 | 0.7901 | 0.8517 | 0.9031 | 0.0908 | 0.8829 | 0.9233 |
| dbCAN_3 | 0.9914 | 0.0474 | 0.9808 | 1.0019 | 0.9421 | 0.0971 | 0.9205 | 0.9637 | 0.9891 | 0.0563 | 0.9766 | 1.0016 | 0.9606 | 0.0790 | 0.9430 | 0.9782 | 0.9751 | 0.0585 | 0.9621 | 0.9881 |
| dbCAN_3:DIAMOND | 0.9893 | 0.0486 | 0.9784 | 1.0001 | 0.9774 | 0.0897 | 0.9574 | 0.9973 | 0.9839 | 0.0620 | 0.9701 | 0.9977 | 0.9764 | 0.0755 | 0.9596 | 0.9932 | 0.9848 | 0.0567 | 0.9722 | 0.9974 |
| dbCAN_3:eCAMI | 0.9922 | 0.0439 | 0.9824 | 1.0019 | 0.8500 | 0.1524 | 0.8161 | 0.8839 | 0.9881 | 0.0572 | 0.9754 | 1.0009 | 0.9046 | 0.1076 | 0.8806 | 0.9285 | 0.9413 | 0.0822 | 0.9230 | 0.9596 |
| dbCAN_3:HMMER | 0.9904 | 0.0487 | 0.9796 | 1.0012 | 0.8654 | 0.1113 | 0.8406 | 0.8901 | 0.9884 | 0.0566 | 0.9758 | 1.0010 | 0.9169 | 0.0839 | 0.8982 | 0.9355 | 0.9503 | 0.0597 | 0.9370 | 0.9635 |
| dbCAN_4 | 0.9900 | 0.0492 | 0.9790 | 1.0009 | 0.9578 | 0.0921 | 0.9373 | 0.9783 | 0.9866 | 0.0566 | 0.9740 | 0.9992 | 0.9677 | 0.0753 | 0.9510 | 0.9845 | 0.9781 | 0.0572 | 0.9654 | 0.9909 |
| dbCAN_4:dbCAN-sub | 0.9900 | 0.0492 | 0.9790 | 1.0009 | 0.9538 | 0.0835 | 0.9352 | 0.9724 | 0.9866 | 0.0566 | 0.9740 | 0.9992 | 0.9664 | 0.0656 | 0.9518 | 0.9810 | 0.9773 | 0.0519 | 0.9657 | 0.9889 |
| dbCAN_4:DIAMOND | 0.9893 | 0.0488 | 0.9785 | 1.0002 | 0.9751 | 0.0914 | 0.9548 | 0.9954 | 0.9841 | 0.0638 | 0.9699 | 0.9983 | 0.9750 | 0.0781 | 0.9577 | 0.9924 | 0.9838 | 0.0577 | 0.9710 | 0.9966 |
| dbCAN_4:HMMER | 0.9904 | 0.0487 | 0.9796 | 1.0012 | 0.8657 | 0.1110 | 0.8410 | 0.8904 | 0.9884 | 0.0566 | 0.9758 | 1.0010 | 0.9170 | 0.0838 | 0.8984 | 0.9357 | 0.9503 | 0.0597 | 0.9370 | 0.9635 |
Figure 6.8: Scatter plot of sensitivity against specificity for predicting GT CAZy class members per CAZyme classier, overlaying a density map.
Figure 6.9: Summary statistics of CAZyme classifiers performances of GT class classification, plotting the mean plus and minus the 95% confidence interval.
Figure 6.10: One dimensional scatter plot of the statistical parameters per test set for the classification of GT class members, overlaying a box plot
| Prediction_tool | Spec Mean | Spec Standard Deviation | Spec CI Lower | Spec CI Upper | Sens Mean | Sens Standard Deviation | Sens CI Lower | Sens CI Upper | Prec Mean | Prec Standard Deviation | Prec CI Lower | Prec CI Upper | F1-score Mean | F1-score Standard Deviation | F1-score CI Lower | F1-score CI Upper | Acc Mean | Acc Standard Deviation | Acc CI Lower | Acc CI Upper |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CUPP | 0.9996 | 0.0019 | 0.9990 | 1.0002 | 0.8511 | 0.2593 | 0.7749 | 0.9272 | 0.9496 | 0.2058 | 0.8892 | 1.0101 | 0.8850 | 0.2288 | 0.8178 | 0.9522 | 0.9941 | 0.0096 | 0.9913 | 0.9970 |
| dbCAN_2 | 0.9998 | 0.0012 | 0.9995 | 1.0002 | 0.8797 | 0.2421 | 0.8086 | 0.9508 | 0.9532 | 0.2052 | 0.8929 | 1.0134 | 0.9073 | 0.2183 | 0.8432 | 0.9714 | 0.9959 | 0.0070 | 0.9938 | 0.9979 |
| dbCAN_2:DIAMOND | 0.9996 | 0.0019 | 0.9991 | 1.0002 | 0.8691 | 0.2687 | 0.7902 | 0.9480 | 0.9248 | 0.2505 | 0.8513 | 0.9984 | 0.8889 | 0.2530 | 0.8146 | 0.9632 | 0.9954 | 0.0073 | 0.9933 | 0.9976 |
| dbCAN_2:HMMER | 0.9998 | 0.0012 | 0.9995 | 1.0002 | 0.8975 | 0.2125 | 0.8351 | 0.9598 | 0.9745 | 0.1481 | 0.9310 | 1.0180 | 0.9250 | 0.1788 | 0.8725 | 0.9775 | 0.9963 | 0.0062 | 0.9944 | 0.9981 |
| dbCAN_2:Hotpep | 0.9993 | 0.0027 | 0.9985 | 1.0001 | 0.8407 | 0.2581 | 0.7650 | 0.9165 | 0.9506 | 0.2050 | 0.8904 | 1.0108 | 0.8803 | 0.2257 | 0.8140 | 0.9465 | 0.9929 | 0.0131 | 0.9891 | 0.9968 |
| dbCAN_3 | 0.9994 | 0.0025 | 0.9986 | 1.0001 | 0.9881 | 0.0732 | 0.9666 | 1.0096 | 0.9846 | 0.0766 | 0.9621 | 1.0071 | 0.9826 | 0.0689 | 0.9624 | 1.0028 | 0.9990 | 0.0030 | 0.9981 | 0.9999 |
| dbCAN_3:DIAMOND | 0.9989 | 0.0039 | 0.9978 | 1.0000 | 0.9881 | 0.0732 | 0.9666 | 1.0096 | 0.9730 | 0.1012 | 0.9433 | 1.0028 | 0.9754 | 0.0792 | 0.9521 | 0.9986 | 0.9985 | 0.0041 | 0.9973 | 0.9997 |
| dbCAN_3:eCAMI | 0.9996 | 0.0018 | 0.9991 | 1.0002 | 0.7960 | 0.2776 | 0.7154 | 0.8766 | 0.9333 | 0.2452 | 0.8621 | 1.0045 | 0.8473 | 0.2533 | 0.7737 | 0.9208 | 0.9920 | 0.0129 | 0.9883 | 0.9958 |
| dbCAN_3:HMMER | 0.9994 | 0.0025 | 0.9986 | 1.0001 | 0.9739 | 0.0982 | 0.9451 | 1.0028 | 0.9846 | 0.0766 | 0.9621 | 1.0071 | 0.9741 | 0.0781 | 0.9511 | 0.9970 | 0.9986 | 0.0035 | 0.9975 | 0.9996 |
| dbCAN_4 | 0.9994 | 0.0025 | 0.9986 | 1.0001 | 0.9739 | 0.0982 | 0.9451 | 1.0028 | 0.9846 | 0.0766 | 0.9621 | 1.0071 | 0.9741 | 0.0781 | 0.9511 | 0.9970 | 0.9986 | 0.0035 | 0.9975 | 0.9996 |
| dbCAN_4:dbCAN-sub | 0.9994 | 0.0025 | 0.9986 | 1.0001 | 0.9752 | 0.0982 | 0.9464 | 1.0040 | 0.9846 | 0.0766 | 0.9621 | 1.0071 | 0.9747 | 0.0782 | 0.9518 | 0.9977 | 0.9988 | 0.0032 | 0.9978 | 0.9997 |
| dbCAN_4:DIAMOND | 0.9989 | 0.0039 | 0.9978 | 1.0000 | 0.9987 | 0.0086 | 0.9962 | 1.0013 | 0.9730 | 0.1012 | 0.9433 | 1.0028 | 0.9825 | 0.0646 | 0.9635 | 1.0014 | 0.9988 | 0.0039 | 0.9976 | 0.9999 |
| dbCAN_4:HMMER | 0.9994 | 0.0025 | 0.9986 | 1.0001 | 0.9739 | 0.0982 | 0.9451 | 1.0028 | 0.9846 | 0.0766 | 0.9621 | 1.0071 | 0.9741 | 0.0781 | 0.9511 | 0.9970 | 0.9986 | 0.0035 | 0.9975 | 0.9996 |
Figure 6.11: Scatter plot of sensitivity against specificity for predicting PL CAZy class members per CAZyme classier, overlaying a density map.
Figure 6.12: Summary statistics of CAZyme classifiers performances of PL class classification, plotting the mean plus and minus the 95% confidence interval.
Figure 6.13: One dimensional scatter plot of the statistical parameters per test set for the classification of PL class members, overlaying a box plot
| Prediction_tool | Spec Mean | Spec Standard Deviation | Spec CI Lower | Spec CI Upper | Sens Mean | Sens Standard Deviation | Sens CI Lower | Sens CI Upper | Prec Mean | Prec Standard Deviation | Prec CI Lower | Prec CI Upper | F1-score Mean | F1-score Standard Deviation | F1-score CI Lower | F1-score CI Upper | Acc Mean | Acc Standard Deviation | Acc CI Lower | Acc CI Upper |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CUPP | 0.9955 | 0.0178 | 0.9914 | 0.9995 | 0.9114 | 0.1332 | 0.8810 | 0.9419 | 0.9598 | 0.1130 | 0.9339 | 0.9856 | 0.9250 | 0.1095 | 0.9000 | 0.9500 | 0.9900 | 0.0187 | 0.9857 | 0.9943 |
| dbCAN_2 | 0.9937 | 0.0220 | 0.9887 | 0.9988 | 0.9213 | 0.1433 | 0.8886 | 0.9540 | 0.9519 | 0.1408 | 0.9197 | 0.9840 | 0.9224 | 0.1305 | 0.8926 | 0.9522 | 0.9893 | 0.0225 | 0.9842 | 0.9945 |
| dbCAN_2:DIAMOND | 0.9941 | 0.0210 | 0.9893 | 0.9989 | 0.8480 | 0.2469 | 0.7915 | 0.9044 | 0.9280 | 0.2089 | 0.8803 | 0.9757 | 0.8636 | 0.2234 | 0.8126 | 0.9147 | 0.9862 | 0.0242 | 0.9807 | 0.9918 |
| dbCAN_2:HMMER | 0.9945 | 0.0187 | 0.9902 | 0.9988 | 0.9208 | 0.1363 | 0.8896 | 0.9519 | 0.9525 | 0.1191 | 0.9253 | 0.9797 | 0.9248 | 0.1119 | 0.8993 | 0.9504 | 0.9901 | 0.0189 | 0.9858 | 0.9945 |
| dbCAN_2:Hotpep | 0.9905 | 0.0229 | 0.9852 | 0.9957 | 0.8508 | 0.2065 | 0.8036 | 0.8980 | 0.9128 | 0.1671 | 0.8746 | 0.9510 | 0.8555 | 0.1705 | 0.8165 | 0.8944 | 0.9821 | 0.0251 | 0.9764 | 0.9878 |
| dbCAN_3 | 0.9936 | 0.0224 | 0.9885 | 0.9988 | 0.9283 | 0.1537 | 0.8932 | 0.9634 | 0.9526 | 0.1391 | 0.9208 | 0.9844 | 0.9236 | 0.1397 | 0.8916 | 0.9555 | 0.9896 | 0.0220 | 0.9846 | 0.9946 |
| dbCAN_3:DIAMOND | 0.9925 | 0.0234 | 0.9872 | 0.9979 | 0.9303 | 0.1704 | 0.8913 | 0.9692 | 0.9304 | 0.1864 | 0.8878 | 0.9730 | 0.9152 | 0.1682 | 0.8768 | 0.9537 | 0.9890 | 0.0231 | 0.9837 | 0.9943 |
| dbCAN_3:eCAMI | 0.9926 | 0.0213 | 0.9877 | 0.9975 | 0.8073 | 0.2445 | 0.7514 | 0.8632 | 0.9156 | 0.1909 | 0.8719 | 0.9592 | 0.8314 | 0.2020 | 0.7852 | 0.8775 | 0.9818 | 0.0249 | 0.9761 | 0.9875 |
| dbCAN_3:HMMER | 0.9953 | 0.0179 | 0.9912 | 0.9994 | 0.9230 | 0.1335 | 0.8925 | 0.9535 | 0.9602 | 0.1103 | 0.9350 | 0.9854 | 0.9302 | 0.1073 | 0.9057 | 0.9547 | 0.9910 | 0.0177 | 0.9870 | 0.9951 |
| dbCAN_4 | 0.9953 | 0.0179 | 0.9912 | 0.9994 | 0.9783 | 0.0669 | 0.9630 | 0.9935 | 0.9603 | 0.1103 | 0.9351 | 0.9855 | 0.9638 | 0.0854 | 0.9443 | 0.9833 | 0.9943 | 0.0172 | 0.9904 | 0.9982 |
| dbCAN_4:dbCAN-sub | 0.9952 | 0.0181 | 0.9911 | 0.9993 | 0.9755 | 0.0680 | 0.9599 | 0.9910 | 0.9592 | 0.1120 | 0.9336 | 0.9848 | 0.9617 | 0.0863 | 0.9420 | 0.9814 | 0.9938 | 0.0175 | 0.9898 | 0.9978 |
| dbCAN_4:DIAMOND | 0.9931 | 0.0227 | 0.9879 | 0.9983 | 0.9755 | 0.0851 | 0.9560 | 0.9949 | 0.9476 | 0.1506 | 0.9132 | 0.9820 | 0.9507 | 0.1192 | 0.9234 | 0.9779 | 0.9919 | 0.0218 | 0.9870 | 0.9969 |
| dbCAN_4:HMMER | 0.9953 | 0.0179 | 0.9912 | 0.9994 | 0.9529 | 0.1012 | 0.9298 | 0.9760 | 0.9603 | 0.1103 | 0.9351 | 0.9855 | 0.9487 | 0.0957 | 0.9268 | 0.9706 | 0.9929 | 0.0173 | 0.9889 | 0.9968 |
Figure 6.14: Scatter plot of sensitivity against specificity for predicting CE CAZy class members per CAZyme classier, overlaying a density map.
Figure 6.15: Summary statistics of CAZyme classifiers performances of CE class classification, plotting the mean plus and minus the 95% confidence interval.
Figure 6.16: One dimensional scatter plot of the statistical parameters per test set for the classification of CE class members, overlaying a box plot
| Prediction_tool | Spec Mean | Spec Standard Deviation | Spec CI Lower | Spec CI Upper | Sens Mean | Sens Standard Deviation | Sens CI Lower | Sens CI Upper | Prec Mean | Prec Standard Deviation | Prec CI Lower | Prec CI Upper | F1-score Mean | F1-score Standard Deviation | F1-score CI Lower | F1-score CI Upper | Acc Mean | Acc Standard Deviation | Acc CI Lower | Acc CI Upper |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CUPP | 0.9919 | 0.0175 | 0.9868 | 0.9970 | 0.9047 | 0.1300 | 0.8670 | 0.9425 | 0.9184 | 0.1697 | 0.8691 | 0.9677 | 0.9011 | 0.1376 | 0.8611 | 0.9410 | 0.9841 | 0.0215 | 0.9778 | 0.9903 |
| dbCAN_2 | 0.9919 | 0.0178 | 0.9868 | 0.9971 | 0.9190 | 0.1152 | 0.8855 | 0.9524 | 0.9208 | 0.1693 | 0.8716 | 0.9699 | 0.9104 | 0.1322 | 0.8720 | 0.9488 | 0.9856 | 0.0204 | 0.9796 | 0.9915 |
| dbCAN_2:DIAMOND | 0.9922 | 0.0178 | 0.9870 | 0.9974 | 0.8693 | 0.1786 | 0.8174 | 0.9212 | 0.9228 | 0.1710 | 0.8731 | 0.9724 | 0.8766 | 0.1603 | 0.8301 | 0.9232 | 0.9837 | 0.0212 | 0.9775 | 0.9899 |
| dbCAN_2:HMMER | 0.9913 | 0.0187 | 0.9859 | 0.9967 | 0.9375 | 0.0917 | 0.9109 | 0.9641 | 0.9191 | 0.1607 | 0.8724 | 0.9658 | 0.9173 | 0.1137 | 0.8843 | 0.9503 | 0.9856 | 0.0202 | 0.9797 | 0.9914 |
| dbCAN_2:Hotpep | 0.9920 | 0.0180 | 0.9867 | 0.9972 | 0.8737 | 0.1942 | 0.8173 | 0.9301 | 0.8983 | 0.2166 | 0.8354 | 0.9612 | 0.8733 | 0.1924 | 0.8174 | 0.9292 | 0.9827 | 0.0227 | 0.9761 | 0.9893 |
| dbCAN_3 | 0.9911 | 0.0199 | 0.9853 | 0.9969 | 0.9835 | 0.0450 | 0.9705 | 0.9966 | 0.9236 | 0.1605 | 0.8770 | 0.9702 | 0.9436 | 0.1100 | 0.9117 | 0.9756 | 0.9901 | 0.0188 | 0.9846 | 0.9955 |
| dbCAN_3:DIAMOND | 0.9900 | 0.0219 | 0.9837 | 0.9964 | 0.9884 | 0.0359 | 0.9779 | 0.9988 | 0.9171 | 0.1693 | 0.8679 | 0.9662 | 0.9413 | 0.1144 | 0.9080 | 0.9745 | 0.9897 | 0.0200 | 0.9839 | 0.9955 |
| dbCAN_3:eCAMI | 0.9921 | 0.0167 | 0.9873 | 0.9970 | 0.7821 | 0.2611 | 0.7063 | 0.8579 | 0.8514 | 0.2809 | 0.7699 | 0.9330 | 0.8006 | 0.2558 | 0.7263 | 0.8749 | 0.9791 | 0.0233 | 0.9724 | 0.9859 |
| dbCAN_3:HMMER | 0.9907 | 0.0202 | 0.9848 | 0.9965 | 0.9880 | 0.0393 | 0.9766 | 0.9994 | 0.9192 | 0.1624 | 0.8720 | 0.9664 | 0.9434 | 0.1112 | 0.9111 | 0.9757 | 0.9901 | 0.0196 | 0.9844 | 0.9958 |
| dbCAN_4 | 0.9907 | 0.0201 | 0.9848 | 0.9965 | 0.9937 | 0.0258 | 0.9862 | 1.0012 | 0.9198 | 0.1610 | 0.8731 | 0.9666 | 0.9464 | 0.1085 | 0.9149 | 0.9779 | 0.9907 | 0.0188 | 0.9853 | 0.9962 |
| dbCAN_4:dbCAN-sub | 0.9905 | 0.0202 | 0.9846 | 0.9963 | 0.9892 | 0.0331 | 0.9796 | 0.9988 | 0.9177 | 0.1620 | 0.8707 | 0.9648 | 0.9430 | 0.1090 | 0.9113 | 0.9746 | 0.9902 | 0.0189 | 0.9847 | 0.9956 |
| dbCAN_4:DIAMOND | 0.9903 | 0.0219 | 0.9839 | 0.9966 | 0.9700 | 0.0952 | 0.9423 | 0.9976 | 0.9196 | 0.1697 | 0.8703 | 0.9689 | 0.9306 | 0.1226 | 0.8950 | 0.9662 | 0.9897 | 0.0198 | 0.9840 | 0.9954 |
| dbCAN_4:HMMER | 0.9907 | 0.0202 | 0.9848 | 0.9965 | 0.9880 | 0.0393 | 0.9766 | 0.9994 | 0.9192 | 0.1624 | 0.8720 | 0.9664 | 0.9434 | 0.1112 | 0.9111 | 0.9757 | 0.9901 | 0.0196 | 0.9844 | 0.9958 |
Figure 6.17: Scatter plot of sensitivity against specificity for predicting AA CAZy class members per CAZyme classier, overlaying a density map.
Figure 6.18: Summary statistics of CAZyme classifiers performances of AA class classification, plotting the mean plus and minus the 95% confidence interval.
Figure 6.19: One dimensional scatter plot of the statistical parameters per test set for the classification of AA class members, overlaying a box plot
| Prediction_tool | Spec Mean | Spec Standard Deviation | Spec CI Lower | Spec CI Upper | Sens Mean | Sens Standard Deviation | Sens CI Lower | Sens CI Upper | Prec Mean | Prec Standard Deviation | Prec CI Lower | Prec CI Upper | F1-score Mean | F1-score Standard Deviation | F1-score CI Lower | F1-score CI Upper | Acc Mean | Acc Standard Deviation | Acc CI Lower | Acc CI Upper |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CUPP | 1.0000 | 0.0000 | 1.0000 | 1.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.8851 | 0.0851 | 0.8662 | 0.9040 |
| dbCAN_2 | 0.9922 | 0.0119 | 0.9896 | 0.9948 | 0.7242 | 0.1925 | 0.6813 | 0.7670 | 0.9203 | 0.1333 | 0.8906 | 0.9500 | 0.7970 | 0.1542 | 0.7627 | 0.8314 | 0.9656 | 0.0257 | 0.9599 | 0.9713 |
| dbCAN_2:DIAMOND | 0.9914 | 0.0149 | 0.9881 | 0.9947 | 0.7854 | 0.2191 | 0.7367 | 0.8342 | 0.9219 | 0.1502 | 0.8885 | 0.9553 | 0.8325 | 0.1762 | 0.7933 | 0.8717 | 0.9719 | 0.0252 | 0.9663 | 0.9775 |
| dbCAN_2:HMMER | 0.9961 | 0.0088 | 0.9941 | 0.9980 | 0.4129 | 0.2165 | 0.3648 | 0.4611 | 0.8965 | 0.2304 | 0.8452 | 0.9478 | 0.5414 | 0.2150 | 0.4935 | 0.5892 | 0.9378 | 0.0296 | 0.9312 | 0.9444 |
| dbCAN_2:Hotpep | 0.9014 | 0.0511 | 0.8901 | 0.9128 | 0.7061 | 0.2102 | 0.6594 | 0.7529 | 0.4696 | 0.1731 | 0.4311 | 0.5081 | 0.5508 | 0.1723 | 0.5125 | 0.5892 | 0.8823 | 0.0551 | 0.8701 | 0.8946 |
| dbCAN_3 | 0.9943 | 0.0109 | 0.9919 | 0.9968 | 0.7680 | 0.1926 | 0.7252 | 0.8109 | 0.9431 | 0.1355 | 0.9129 | 0.9732 | 0.8354 | 0.1546 | 0.8010 | 0.8698 | 0.9718 | 0.0228 | 0.9667 | 0.9768 |
| dbCAN_3:DIAMOND | 0.9931 | 0.0144 | 0.9899 | 0.9963 | 0.8675 | 0.1731 | 0.8290 | 0.9060 | 0.9512 | 0.1283 | 0.9227 | 0.9797 | 0.8986 | 0.1383 | 0.8678 | 0.9294 | 0.9814 | 0.0185 | 0.9773 | 0.9855 |
| dbCAN_3:eCAMI | 0.9470 | 0.0523 | 0.9354 | 0.9587 | 0.7346 | 0.2203 | 0.6856 | 0.7836 | 0.6615 | 0.2254 | 0.6113 | 0.7117 | 0.6810 | 0.2079 | 0.6347 | 0.7272 | 0.9267 | 0.0565 | 0.9141 | 0.9392 |
| dbCAN_3:HMMER | 0.9960 | 0.0088 | 0.9941 | 0.9980 | 0.4135 | 0.2148 | 0.3657 | 0.4613 | 0.8964 | 0.2304 | 0.8451 | 0.9476 | 0.5425 | 0.2134 | 0.4950 | 0.5900 | 0.9379 | 0.0300 | 0.9313 | 0.9446 |
| dbCAN_4 | 0.9951 | 0.0103 | 0.9928 | 0.9974 | 0.7995 | 0.1921 | 0.7567 | 0.8422 | 0.9562 | 0.0919 | 0.9358 | 0.9767 | 0.8547 | 0.1392 | 0.8237 | 0.8857 | 0.9763 | 0.0207 | 0.9717 | 0.9809 |
| dbCAN_4:dbCAN-sub | 0.9927 | 0.0129 | 0.9898 | 0.9955 | 0.8193 | 0.1995 | 0.7749 | 0.8637 | 0.9376 | 0.1151 | 0.9120 | 0.9632 | 0.8576 | 0.1492 | 0.8244 | 0.8908 | 0.9761 | 0.0244 | 0.9707 | 0.9816 |
| dbCAN_4:DIAMOND | 0.9938 | 0.0146 | 0.9906 | 0.9970 | 0.8773 | 0.1695 | 0.8396 | 0.9151 | 0.9571 | 0.1273 | 0.9288 | 0.9854 | 0.9072 | 0.1362 | 0.8768 | 0.9375 | 0.9830 | 0.0182 | 0.9790 | 0.9870 |
| dbCAN_4:HMMER | 0.9958 | 0.0097 | 0.9937 | 0.9980 | 0.4740 | 0.2360 | 0.4215 | 0.5266 | 0.9184 | 0.1999 | 0.8739 | 0.9629 | 0.5954 | 0.2202 | 0.5464 | 0.6444 | 0.9436 | 0.0300 | 0.9370 | 0.9503 |
Figure 6.20: Scatter plot of sensitivity against specificity for predicting CBM CAZy class members per CAZyme classier, overlaying a density map.
Figure 6.21: Summary statistics of CAZyme classifiers performances of CBM class classification, plotting the mean plus and minus the 95% confidence interval.
Figure 6.22: One dimensional scatter plot of the statistical parameters per test set for the classification of CBM class members, overlaying a box plot
Instead of facet wrapping the plots by statistic and producing a plot per CAZy class, we can produce a plot per statistic (sensitivity, precision, etc.) and facet wrap by CAZy class to facilitate comparing between CAZy classes, and evaluting the performance statistic by statistic.
A single CAZyme can be included in multiple CAZy classes leading to the multilabel classification of CAZymes. To address this and evaluate the multilabel classification of CAZy classes the Rand Index (RI) and Adjusted Rand Index (ARI) were calculated.
The RI is the measure of accuracy across all potential classifications of a protein. The RI ranges from 0 (no correct annotations) to 1 (all annotations correct). The ARI is the RI adjusted for chance, where 0 is the equivalent to assigning the CAZy class annotations randomly, -1 where the annotations are systematically handed out incorrectly and 1 where the annotations are all correct.
build.tax.class.stat.sum <- function(bact.df, euk.df, all.df, stat.param){
# have Three dfs, all with the same structure
# cols = X, Genomic_accession, Prediction_tool, CAZy_class, Statistic_parameter, Statistic_value
# cazy_class_df: all.df - contains data for all test sets
# bact.cazy_class_df: bact.df - only bacteria test sets - therefore, half the length of cazy_class_df
# euk.cazy_class_df: euk.df - only eukaryotic test sets - therefore, half the length of cazy_class_df
# subset stat param
bact.df.stat <- bact.df[which(bact.df$Statistic_parameter == stat.param), ]
bact.df.stat <- bact.df.stat[complete.cases(bact.df.stat), ]
bact.df.stat.sum <- bact.df.stat %>% dplyr::group_by(Prediction_tool) %>% dplyr::summarise(
"Mean"=mean(Statistic_value),
"Standard Deviation"=sd(Statistic_value),
"Lower CI"=CI(Statistic_value)[3],
"Upper CI"=CI(Statistic_value)[1]
)
bact.df.stat.sum$Tax_group = rep("Bacteria", nrow(bact.df.stat.sum))
euk.df.stat <- euk.df[which(euk.df$Statistic_parameter == stat.param), ]
euk.df.stat <- euk.df.stat[complete.cases(euk.df.stat), ]
euk.df.stat.sum <- euk.df.stat %>% dplyr::group_by(Prediction_tool) %>% dplyr::summarise(
"Mean"=mean(Statistic_value),
"Standard Deviation"=sd(Statistic_value),
"Lower CI"=CI(Statistic_value)[3],
"Upper CI"=CI(Statistic_value)[1]
)
euk.df.stat.sum$Tax_group = rep("Eukaryote", nrow(euk.df.stat.sum))
all.df.stat <- all.df[which(all.df$Statistic_parameter == stat.param), ]
all.df.stat <- all.df.stat[complete.cases(all.df.stat), ]
all.df.stat.sum <- all.df.stat %>% dplyr::group_by(Prediction_tool) %>% dplyr::summarise(
"Mean"=mean(Statistic_value),
"Standard Deviation"=sd(Statistic_value),
"Lower CI"=CI(Statistic_value)[3],
"Upper CI"=CI(Statistic_value)[1]
)
all.df.stat.sum$Tax_group <- rep("All", nrow(all.df.stat.sum))
df.stat.sum <- rbind(all.df.stat.sum, bact.df.stat.sum)
df.stat.sum <- rbind(df.stat.sum, euk.df.stat.sum)
df.stat.sum$Prediction_tool <- factor(df.stat.sum$Prediction_tool, levels=classifiers_full, ordered = TRUE) # set order data is presented
return(df.stat.sum)
}
build.class.tax.p.scatter <- function(bact.df.stat, euk.df.stat, all.df.stat, stat.param){
bact.df.stat <- bact.df.stat[which(bact.df.stat$Statistic_parameter == stat.param), ]
bact.df.stat <- bact.df.stat[complete.cases(bact.df.stat), ]
bact.df.stat$Tax_group = rep("Bacteria", nrow(bact.df.stat))
euk.df.stat <- euk.df.stat[which(euk.df.stat$Statistic_parameter == stat.param), ]
euk.df.stat <- euk.df.stat[complete.cases(euk.df.stat), ]
euk.df.stat$Tax_group = rep("Eukaryote", nrow(euk.df.stat))
all.df.stat <- all.df.stat[which(all.df.stat$Statistic_parameter == stat.param), ]
all.df.stat <- all.df.stat[complete.cases(all.df.stat), ]
all.df.stat$Tax_group <- rep('All', nrow(all.df.stat))
df.stat.all <- rbind(all.df.stat, bact.df.stat)
df.stat.all <- rbind(df.stat.all, euk.df.stat)
class.stat.scat.p = ggplot(df.stat.all %>% dplyr::group_by(Prediction_tool),
aes(x=Tax_group, y=Statistic_value, fill=Tax_group)) +
geom_boxplot(outlier.shape=NA) +
geom_jitter(width=0.1, height=0, size=0.3) +
geom_hline(yintercept=0.95, linetype="dashed", color ="#5c5c5c") +
geom_hline(yintercept=0.9, linetype="dashed", color = "#5c5c5c") +
scale_fill_manual(values = colour_set) +
theme(legend.position = "none",
plot.background = element_rect(fill = figbg, color = figbg),
axis.text=element_text(size=10),
axis.title=element_text(size=11,face="bold")) +
xlab("Kingdom") +
ylab(stat.param) +
facet_wrap(~ Prediction_tool, ncol=2)
return(class.stat.scat.p)
}
build.class.tax.p <- function(stat_sum_df, stat.val){
colnames(stat_sum_df) <- c('Prediction_tool', 'Mean', 'SD', 'LowerCI', 'UpperCI', 'Taxonomic_group')
stat_sum_df$Prediction_tool <- factor(stat_sum_df$Prediction_tool, levels = classifiers_full)
p.t.b.ci <- ggplot(stat_sum_df %>% dplyr::group_by(Taxonomic_group),
aes(x=Taxonomic_group, y=Mean, color=Taxonomic_group)) +
geom_point() +
geom_errorbar(aes(ymin=LowerCI, ymax=UpperCI)) +
geom_hline(yintercept=0.95, linetype="dashed", color ="#5c5c5c") +
geom_hline(yintercept=0.9, linetype="dashed", color = "#5c5c5c") +
scale_colour_manual(values = colour_set) +
theme(legend.position = "none",
plot.background = element_rect(fill = figbg, color = figbg),
axis.text=element_text(size=10),
axis.title=element_text(size=12,face="bold")) +
xlab("Classifier") +
ylab(stat.val) +
facet_wrap(~ Prediction_tool, ncol=2)
return(p.t.b.ci)
}
| Prediction_tool | Mean | Standard Deviation | Lower CI | Upper CI | Tax_group |
|---|---|---|---|---|---|
| dbCAN_2 | 0.9933 | 0.0259 | 0.9908 | 0.9958 | All |
| dbCAN_2:HMMER | 0.9939 | 0.0264 | 0.9913 | 0.9964 | All |
| dbCAN_2:DIAMOND | 0.9920 | 0.0270 | 0.9894 | 0.9946 | All |
| dbCAN_2:Hotpep | 0.9733 | 0.0491 | 0.9685 | 0.9781 | All |
| dbCAN_3 | 0.9934 | 0.0265 | 0.9909 | 0.9960 | All |
| dbCAN_3:HMMER | 0.9941 | 0.0261 | 0.9916 | 0.9967 | All |
| dbCAN_3:DIAMOND | 0.9909 | 0.0289 | 0.9881 | 0.9937 | All |
| dbCAN_3:eCAMI | 0.9829 | 0.0388 | 0.9791 | 0.9867 | All |
| dbCAN_4 | 0.9936 | 0.0267 | 0.9910 | 0.9962 | All |
| dbCAN_4:HMMER | 0.9941 | 0.0262 | 0.9915 | 0.9966 | All |
| dbCAN_4:DIAMOND | 0.9915 | 0.0285 | 0.9888 | 0.9943 | All |
| dbCAN_4:dbCAN-sub | 0.9931 | 0.0269 | 0.9905 | 0.9957 | All |
| CUPP | 0.9953 | 0.0246 | 0.9929 | 0.9977 | All |
| dbCAN_2 | 0.9951 | 0.0157 | 0.9930 | 0.9973 | Bacteria |
| dbCAN_2:HMMER | 0.9959 | 0.0139 | 0.9939 | 0.9978 | Bacteria |
| dbCAN_2:DIAMOND | 0.9932 | 0.0185 | 0.9907 | 0.9958 | Bacteria |
| dbCAN_2:Hotpep | 0.9695 | 0.0509 | 0.9625 | 0.9766 | Bacteria |
| dbCAN_3 | 0.9950 | 0.0160 | 0.9928 | 0.9973 | Bacteria |
| dbCAN_3:HMMER | 0.9962 | 0.0133 | 0.9944 | 0.9981 | Bacteria |
| dbCAN_3:DIAMOND | 0.9930 | 0.0191 | 0.9904 | 0.9957 | Bacteria |
| dbCAN_3:eCAMI | 0.9798 | 0.0392 | 0.9743 | 0.9852 | Bacteria |
| dbCAN_4 | 0.9958 | 0.0137 | 0.9939 | 0.9977 | Bacteria |
| dbCAN_4:HMMER | 0.9962 | 0.0133 | 0.9944 | 0.9981 | Bacteria |
| dbCAN_4:DIAMOND | 0.9942 | 0.0173 | 0.9918 | 0.9966 | Bacteria |
| dbCAN_4:dbCAN-sub | 0.9954 | 0.0139 | 0.9935 | 0.9973 | Bacteria |
| CUPP | 0.9970 | 0.0128 | 0.9952 | 0.9988 | Bacteria |
| dbCAN_2 | 0.9916 | 0.0328 | 0.9871 | 0.9961 | Eukaryote |
| dbCAN_2:HMMER | 0.9920 | 0.0343 | 0.9873 | 0.9967 | Eukaryote |
| dbCAN_2:DIAMOND | 0.9909 | 0.0332 | 0.9864 | 0.9954 | Eukaryote |
| dbCAN_2:Hotpep | 0.9769 | 0.0472 | 0.9705 | 0.9833 | Eukaryote |
| dbCAN_3 | 0.9919 | 0.0335 | 0.9874 | 0.9965 | Eukaryote |
| dbCAN_3:HMMER | 0.9921 | 0.0341 | 0.9875 | 0.9968 | Eukaryote |
| dbCAN_3:DIAMOND | 0.9888 | 0.0357 | 0.9839 | 0.9936 | Eukaryote |
| dbCAN_3:eCAMI | 0.9859 | 0.0382 | 0.9807 | 0.9911 | Eukaryote |
| dbCAN_4 | 0.9916 | 0.0348 | 0.9868 | 0.9963 | Eukaryote |
| dbCAN_4:HMMER | 0.9920 | 0.0341 | 0.9874 | 0.9967 | Eukaryote |
| dbCAN_4:DIAMOND | 0.9890 | 0.0360 | 0.9841 | 0.9939 | Eukaryote |
| dbCAN_4:dbCAN-sub | 0.9908 | 0.0350 | 0.9861 | 0.9956 | Eukaryote |
| CUPP | 0.9937 | 0.0320 | 0.9894 | 0.9981 | Eukaryote |
## png
## 2
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## 2
| Prediction_tool | Mean | Standard Deviation | Lower CI | Upper CI | Tax_group |
|---|---|---|---|---|---|
| dbCAN_2 | 0.8830 | 0.1710 | 0.8592 | 0.9068 | Bacteria |
| dbCAN_2:HMMER | 0.8194 | 0.2217 | 0.7885 | 0.8502 | Bacteria |
| dbCAN_2:DIAMOND | 0.8889 | 0.1819 | 0.8636 | 0.9142 | Bacteria |
| dbCAN_2:Hotpep | 0.8176 | 0.2115 | 0.7882 | 0.8470 | Bacteria |
| dbCAN_3 | 0.9128 | 0.1608 | 0.8905 | 0.9352 | Bacteria |
| dbCAN_3:HMMER | 0.8256 | 0.2214 | 0.7948 | 0.8564 | Bacteria |
| dbCAN_3:DIAMOND | 0.9334 | 0.1427 | 0.9136 | 0.9533 | Bacteria |
| dbCAN_3:eCAMI | 0.8435 | 0.2067 | 0.8148 | 0.8722 | Bacteria |
| dbCAN_4 | 0.9477 | 0.1076 | 0.9327 | 0.9626 | Bacteria |
| dbCAN_4:HMMER | 0.8545 | 0.1946 | 0.8275 | 0.8816 | Bacteria |
| dbCAN_4:DIAMOND | 0.9317 | 0.1461 | 0.9114 | 0.9520 | Bacteria |
| dbCAN_4:dbCAN-sub | 0.9558 | 0.1011 | 0.9417 | 0.9699 | Bacteria |
| CUPP | 0.7168 | 0.3818 | 0.6637 | 0.7699 | Bacteria |
| dbCAN_2 | 0.8644 | 0.1754 | 0.8405 | 0.8882 | Eukaryote |
| dbCAN_2:HMMER | 0.7960 | 0.2670 | 0.7596 | 0.8323 | Eukaryote |
| dbCAN_2:DIAMOND | 0.8583 | 0.2229 | 0.8280 | 0.8887 | Eukaryote |
| dbCAN_2:Hotpep | 0.7877 | 0.1978 | 0.7608 | 0.8146 | Eukaryote |
| dbCAN_3 | 0.9241 | 0.1291 | 0.9066 | 0.9417 | Eukaryote |
| dbCAN_3:HMMER | 0.8252 | 0.2649 | 0.7892 | 0.8613 | Eukaryote |
| dbCAN_3:DIAMOND | 0.9649 | 0.1093 | 0.9500 | 0.9798 | Eukaryote |
| dbCAN_3:eCAMI | 0.7790 | 0.2176 | 0.7494 | 0.8086 | Eukaryote |
| dbCAN_4 | 0.9234 | 0.1457 | 0.9036 | 0.9433 | Eukaryote |
| dbCAN_4:HMMER | 0.8317 | 0.2562 | 0.7968 | 0.8665 | Eukaryote |
| dbCAN_4:DIAMOND | 0.9831 | 0.0487 | 0.9765 | 0.9898 | Eukaryote |
| dbCAN_4:dbCAN-sub | 0.9189 | 0.1433 | 0.8994 | 0.9384 | Eukaryote |
| CUPP | 0.7121 | 0.3682 | 0.6620 | 0.7622 | Eukaryote |
## png
## 2
## png
## 2
| Prediction_tool | Mean | Standard Deviation | Lower CI | Upper CI | Tax_group |
|---|---|---|---|---|---|
| dbCAN_2 | 0.9664 | 0.1215 | 0.9495 | 0.9833 | Bacteria |
| dbCAN_2:HMMER | 0.9706 | 0.0968 | 0.9571 | 0.9840 | Bacteria |
| dbCAN_2:DIAMOND | 0.9647 | 0.1349 | 0.9459 | 0.9834 | Bacteria |
| dbCAN_2:Hotpep | 0.8551 | 0.2420 | 0.8214 | 0.8887 | Bacteria |
| dbCAN_3 | 0.9686 | 0.1160 | 0.9525 | 0.9848 | Bacteria |
| dbCAN_3:HMMER | 0.9725 | 0.0929 | 0.9596 | 0.9854 | Bacteria |
| dbCAN_3:DIAMOND | 0.9712 | 0.1113 | 0.9557 | 0.9867 | Bacteria |
| dbCAN_3:eCAMI | 0.8865 | 0.2140 | 0.8568 | 0.9162 | Bacteria |
| dbCAN_4 | 0.9783 | 0.0746 | 0.9680 | 0.9887 | Bacteria |
| dbCAN_4:HMMER | 0.9755 | 0.0855 | 0.9636 | 0.9873 | Bacteria |
| dbCAN_4:DIAMOND | 0.9734 | 0.1103 | 0.9580 | 0.9887 | Bacteria |
| dbCAN_4:dbCAN-sub | 0.9767 | 0.0751 | 0.9663 | 0.9872 | Bacteria |
| CUPP | 0.7806 | 0.4022 | 0.7246 | 0.8365 | Bacteria |
| dbCAN_2 | 0.9476 | 0.1358 | 0.9291 | 0.9661 | Eukaryote |
| dbCAN_2:HMMER | 0.9390 | 0.1748 | 0.9152 | 0.9628 | Eukaryote |
| dbCAN_2:DIAMOND | 0.9333 | 0.1738 | 0.9097 | 0.9569 | Eukaryote |
| dbCAN_2:Hotpep | 0.8568 | 0.2458 | 0.8233 | 0.8902 | Eukaryote |
| dbCAN_3 | 0.9622 | 0.1043 | 0.9480 | 0.9764 | Eukaryote |
| dbCAN_3:HMMER | 0.9427 | 0.1653 | 0.9202 | 0.9651 | Eukaryote |
| dbCAN_3:DIAMOND | 0.9462 | 0.1359 | 0.9277 | 0.9646 | Eukaryote |
| dbCAN_3:eCAMI | 0.8894 | 0.2221 | 0.8592 | 0.9196 | Eukaryote |
| dbCAN_4 | 0.9589 | 0.1086 | 0.9442 | 0.9737 | Eukaryote |
| dbCAN_4:HMMER | 0.9483 | 0.1511 | 0.9277 | 0.9688 | Eukaryote |
| dbCAN_4:DIAMOND | 0.9537 | 0.1191 | 0.9375 | 0.9699 | Eukaryote |
| dbCAN_4:dbCAN-sub | 0.9524 | 0.1182 | 0.9364 | 0.9685 | Eukaryote |
| CUPP | 0.7765 | 0.3957 | 0.7227 | 0.8304 | Eukaryote |
## png
## 2
## png
## 2
| Prediction_tool | Mean | Standard Deviation | Lower CI | Upper CI | Tax_group |
|---|---|---|---|---|---|
| dbCAN_2 | 0.9120 | 0.1418 | 0.8923 | 0.9317 | Bacteria |
| dbCAN_2:HMMER | 0.8680 | 0.1741 | 0.8438 | 0.8922 | Bacteria |
| dbCAN_2:DIAMOND | 0.9136 | 0.1536 | 0.8922 | 0.9349 | Bacteria |
| dbCAN_2:Hotpep | 0.8140 | 0.2090 | 0.7850 | 0.8431 | Bacteria |
| dbCAN_3 | 0.9298 | 0.1366 | 0.9108 | 0.9488 | Bacteria |
| dbCAN_3:HMMER | 0.8729 | 0.1729 | 0.8489 | 0.8970 | Bacteria |
| dbCAN_3:DIAMOND | 0.9434 | 0.1209 | 0.9266 | 0.9602 | Bacteria |
| dbCAN_3:eCAMI | 0.8506 | 0.1978 | 0.8232 | 0.8781 | Bacteria |
| dbCAN_4 | 0.9567 | 0.0853 | 0.9449 | 0.9686 | Bacteria |
| dbCAN_4:HMMER | 0.8949 | 0.1487 | 0.8742 | 0.9156 | Bacteria |
| dbCAN_4:DIAMOND | 0.9432 | 0.1237 | 0.9260 | 0.9604 | Bacteria |
| dbCAN_4:dbCAN-sub | 0.9607 | 0.0815 | 0.9493 | 0.9720 | Bacteria |
| CUPP | 0.7409 | 0.3859 | 0.6872 | 0.7946 | Bacteria |
| dbCAN_2 | 0.8934 | 0.1458 | 0.8736 | 0.9133 | Eukaryote |
| dbCAN_2:HMMER | 0.8353 | 0.2285 | 0.8042 | 0.8663 | Eukaryote |
| dbCAN_2:DIAMOND | 0.8794 | 0.1936 | 0.8531 | 0.9057 | Eukaryote |
| dbCAN_2:Hotpep | 0.7977 | 0.2034 | 0.7700 | 0.8253 | Eukaryote |
| dbCAN_3 | 0.9339 | 0.1028 | 0.9199 | 0.9478 | Eukaryote |
| dbCAN_3:HMMER | 0.8532 | 0.2236 | 0.8227 | 0.8836 | Eukaryote |
| dbCAN_3:DIAMOND | 0.9484 | 0.1137 | 0.9329 | 0.9638 | Eukaryote |
| dbCAN_3:eCAMI | 0.8147 | 0.2055 | 0.7867 | 0.8426 | Eukaryote |
| dbCAN_4 | 0.9301 | 0.1179 | 0.9140 | 0.9461 | Eukaryote |
| dbCAN_4:HMMER | 0.8591 | 0.2146 | 0.8299 | 0.8883 | Eukaryote |
| dbCAN_4:DIAMOND | 0.9629 | 0.0818 | 0.9517 | 0.9740 | Eukaryote |
| dbCAN_4:dbCAN-sub | 0.9249 | 0.1207 | 0.9085 | 0.9413 | Eukaryote |
| CUPP | 0.7370 | 0.3750 | 0.6860 | 0.7880 | Eukaryote |
## png
## 2
## png
## 2
| Prediction_tool | Mean | Standard Deviation | Lower CI | Upper CI | Tax_group |
|---|---|---|---|---|---|
| dbCAN_2 | 0.9747 | 0.0436 | 0.9687 | 0.9808 | Bacteria |
| dbCAN_2:HMMER | 0.9646 | 0.0478 | 0.9580 | 0.9713 | Bacteria |
| dbCAN_2:DIAMOND | 0.9766 | 0.0455 | 0.9703 | 0.9830 | Bacteria |
| dbCAN_2:Hotpep | 0.9366 | 0.0664 | 0.9274 | 0.9458 | Bacteria |
| dbCAN_3 | 0.9813 | 0.0408 | 0.9757 | 0.9870 | Bacteria |
| dbCAN_3:HMMER | 0.9658 | 0.0480 | 0.9591 | 0.9725 | Bacteria |
| dbCAN_3:DIAMOND | 0.9844 | 0.0387 | 0.9790 | 0.9898 | Bacteria |
| dbCAN_3:eCAMI | 0.9578 | 0.0539 | 0.9503 | 0.9653 | Bacteria |
| dbCAN_4 | 0.9855 | 0.0392 | 0.9801 | 0.9910 | Bacteria |
| dbCAN_4:HMMER | 0.9684 | 0.0473 | 0.9618 | 0.9750 | Bacteria |
| dbCAN_4:DIAMOND | 0.9839 | 0.0400 | 0.9784 | 0.9895 | Bacteria |
| dbCAN_4:dbCAN-sub | 0.9864 | 0.0359 | 0.9814 | 0.9914 | Bacteria |
| CUPP | 0.9516 | 0.0743 | 0.9413 | 0.9620 | Bacteria |
| dbCAN_2 | 0.9728 | 0.0431 | 0.9670 | 0.9787 | Eukaryote |
| dbCAN_2:HMMER | 0.9656 | 0.0332 | 0.9611 | 0.9702 | Eukaryote |
| dbCAN_2:DIAMOND | 0.9759 | 0.0448 | 0.9698 | 0.9820 | Eukaryote |
| dbCAN_2:Hotpep | 0.9401 | 0.0698 | 0.9306 | 0.9496 | Eukaryote |
| dbCAN_3 | 0.9825 | 0.0259 | 0.9790 | 0.9860 | Eukaryote |
| dbCAN_3:HMMER | 0.9690 | 0.0331 | 0.9645 | 0.9735 | Eukaryote |
| dbCAN_3:DIAMOND | 0.9882 | 0.0241 | 0.9850 | 0.9915 | Eukaryote |
| dbCAN_3:eCAMI | 0.9528 | 0.0587 | 0.9449 | 0.9608 | Eukaryote |
| dbCAN_4 | 0.9822 | 0.0252 | 0.9788 | 0.9857 | Eukaryote |
| dbCAN_4:HMMER | 0.9695 | 0.0325 | 0.9650 | 0.9739 | Eukaryote |
| dbCAN_4:DIAMOND | 0.9900 | 0.0226 | 0.9870 | 0.9931 | Eukaryote |
| dbCAN_4:dbCAN-sub | 0.9803 | 0.0264 | 0.9767 | 0.9839 | Eukaryote |
| CUPP | 0.9559 | 0.0466 | 0.9496 | 0.9623 | Eukaryote |
## png
## 2
## png
## 2
build.class.tax.per.class.p <- function(stat_sum_df, stat.val){
# df has colnames:
# Prediction_tool, Mean, Standard Deviation, LowerCI, UpperCI, Tax_group, CAZy_clas
colnames(stat_sum_df) <- c('Prediction_tool', 'Mean', 'SD', 'LowerCI', 'UpperCI', 'Taxonomic_group', 'CAZy_class')
stat_sum_df$Prediction_tool <- factor(stat_sum_df$Prediction_tool, levels = classifiers_full)
stat_sum_df$CAZy_class <- factor(stat_sum_df$CAZy_class, levels=cazy_class_list)
p.t.b.ci <- ggplot(stat_sum_df %>% dplyr::group_by(Prediction_tool) %>% dplyr::group_by(Taxonomic_group),
aes(x=Prediction_tool, y=Mean, color=Taxonomic_group, alpha=0.85)) +
geom_point(aes(shape=Taxonomic_group), position=position_dodge(width=0.75)) +
geom_errorbar(aes(ymin=LowerCI, ymax=UpperCI), width = 1, position=position_dodge(width=0.75)) +
geom_hline(yintercept=0.95, linetype="dashed", color ="#5c5c5c") +
geom_hline(yintercept=0.9, linetype="dashed", color = "#5c5c5c") +
geom_vline(xintercept=stat_sum_df$Prediction_tool, linetype="dashed", color = "#9c9c9c") +
scale_colour_manual(values = colour_set) +
theme(legend.position = "bottom",
plot.background = element_rect(fill = figbg, color = figbg),
axis.text=element_text(size=10),
axis.title=element_text(size=12,face="bold"),
axis.text.x=element_text(angle = 90, size=9, vjust=0.45)) +
xlab("Classifier") +
ylab(stat.val) +
facet_wrap(~ CAZy_class, ncol=2)
return(p.t.b.ci)
}
build.class.tax.p.scatter.per.cl <- function(all.df.stat, bact.df.stat, euk.df.stat, stat.param){
bact.df.stat <- bact.df.stat[which(bact.df.stat$Statistic_parameter == stat.param), ]
bact.df.stat <- bact.df.stat[complete.cases(bact.df.stat), ]
bact.df.stat$Tax_group = rep("Bacteria", nrow(bact.df.stat))
euk.df.stat <- euk.df.stat[which(euk.df.stat$Statistic_parameter == stat.param), ]
euk.df.stat <- euk.df.stat[complete.cases(euk.df.stat), ]
euk.df.stat$Tax_group = rep("Eukaryote", nrow(euk.df.stat))
all.df.stat <- all.df.stat[which(all.df.stat$Statistic_parameter == stat.param), ]
all.df.stat <- all.df.stat[complete.cases(all.df.stat), ]
all.df.stat$Tax_group <- rep('All', nrow(all.df.stat))
all.df.stat <- rbind(all.df.stat, bact.df.stat)
all.df.stat <- rbind(all.df.stat, euk.df.stat)
all.df.stat$Prediction_tool <- factor(all.df.stat$Prediction_tool, levels = classifiers_full)
all.df.stat$CAZy_class <- factor(all.df.stat$CAZy_class, levels=cazy_class_list)
class.stat.scat.p = ggplot(all.df.stat %>% dplyr::group_by(Prediction_tool) %>% dplyr::group_by(Tax_group),
aes(x=Prediction_tool, y=Statistic_value, fill=Tax_group)) +
geom_boxplot(outlier.shape=NA, position=position_dodge(width=1)) +
geom_jitter(position=position_dodge(width=1), size=0.3, aes(alpha=0.5)) +
geom_hline(yintercept=0.95, linetype="dashed", color ="#5c5c5c") +
geom_hline(yintercept=0.9, linetype="dashed", color = "#5c5c5c") +
geom_vline(xintercept=all.df.stat$Prediction_tool, linetype="dashed", color = "#9c9c9c") +
scale_fill_manual(values = colour_set) +
theme(legend.position = "none",
plot.background = element_rect(fill = figbg, color = figbg),
axis.text=element_text(size=10),
axis.title=element_text(size=11,face="bold"),
axis.text.x=element_text(angle = 90, size=8, vjust=0.45)) +
xlab("Kingdom") +
ylab(stat.param) +
facet_wrap(~ CAZy_class, ncol=2)
return(class.stat.scat.p)
}
build.class.tax.sum.GH <- function(cazy.class.df, bact.class.df, euk.class.df, stat_param){
# 3 dataframes have the same structure.
# colnames: "X", "Genomic_accession", "Prediction_tool", "CAZy_class", "Statistic_parameter", "Statistic_value"
# subset for CAZy class
bact.class_df.class <- bact.class.df[which(bact.class.df$CAZy_class == "GH"), ]
euk.class_df.class <- euk.class.df[which(euk.class.df$CAZy_class == "GH"), ]
cazy.class.df.class <- cazy.class.df[which(cazy.class.df$CAZy_class == "GH"), ]
# subset statistical parameter
bact.class_df.stat <- bact.class_df.class[which(bact.class_df.class$Statistic_parameter == stat_param), ]
euk.class_df.stat <- euk.class_df.class[which(euk.class_df.class$Statistic_parameter == stat_param), ]
cazy.class.df.stat <- cazy.class.df.class[which(cazy.class.df.class$Statistic_parameter == stat_param), ]
bact.class_df.stat <- bact.class_df.stat[complete.cases(bact.class_df.stat), ]
euk.class_df.stat <- euk.class_df.stat[complete.cases(euk.class_df.stat), ]
cazy.class.df.stat <- cazy.class.df.stat[complete.cases(cazy.class.df.stat), ]
# calculate stats
bact.means <- bact.class_df.stat %>% dplyr::group_by(Prediction_tool) %>% dplyr::summarise(
"Mean"=mean(Statistic_value),
"Standard Deviation"=sd(Statistic_value),
"LowerCI"=CI(Statistic_value)[3],
"UpperCI"=CI(Statistic_value)[1]
)
euk.means <- euk.class_df.stat %>% dplyr::group_by(Prediction_tool) %>% dplyr::summarise(
"Mean"=mean(Statistic_value),
"Standard Deviation"=sd(Statistic_value),
"LowerCI"=CI(Statistic_value)[3],
"UpperCI"=CI(Statistic_value)[1]
)
all.means <- cazy.class.df.stat %>% dplyr::group_by(Prediction_tool) %>% dplyr::summarise(
"Mean"=mean(Statistic_value),
"Standard Deviation"=sd(Statistic_value),
"LowerCI"=CI(Statistic_value)[3],
"UpperCI"=CI(Statistic_value)[1]
)
all.means$Tax_group <- rep("All", nrow(all.means))
bact.means$Tax_group <- rep("Bacteria", nrow(bact.means))
euk.means$Tax_group <- rep("Eukaryote", nrow(euk.means))
class_df.class.stat.tax <- rbind(all.means, bact.means)
class_df.class.stat.tax <- rbind(class_df.class.stat.tax, euk.means)
class_df.class.stat.tax$Prediction_tool <- factor(class_df.class.stat.tax$Prediction_tool, levels=classifiers_full)
class_df.class.stat.tax$CAZy_class <- rep("GH", nrow(class_df.class.stat.tax))
return(class_df.class.stat.tax)
}
build.class.tax.sum.class <- function(cazy.class.df, bact.class.df, euk.class.df, stat_param, cazy_class){
# subset for CAZy class
bact.class_df.class <- bact.class.df[which(bact.class.df$CAZy_class == cazy_class), ]
euk.class_df.class <- euk.class.df[which(euk.class.df$CAZy_class == cazy_class), ]
all.class_df.class <- cazy.class.df[which(cazy.class.df$CAZy_class == cazy_class), ]
# subset statistical parameter
bact.class_df.stat <- bact.class_df.class[which(bact.class_df.class$Statistic_parameter == stat_param), ]
euk.class_df.stat <- euk.class_df.class[which(euk.class_df.class$Statistic_parameter == stat_param), ]
all.class_df.stat <- all.class_df.class[which(all.class_df.class$Statistic_parameter == stat_param), ]
bact.class_df.stat <- bact.class_df.stat[complete.cases(bact.class_df.stat), ]
euk.class_df.stat <- euk.class_df.stat[complete.cases(euk.class_df.stat), ]
all.class_df.stat <- all.class_df.stat[complete.cases(all.class_df.stat), ]
# calculate stats
bact.means <- bact.class_df.stat %>% dplyr::group_by(Prediction_tool) %>% dplyr::summarise(
"Mean"=mean(Statistic_value),
"Standard Deviation"=sd(Statistic_value),
"LowerCI"=CI(Statistic_value)[3],
"UpperCI"=CI(Statistic_value)[1]
)
euk.means <- euk.class_df.stat %>% dplyr::group_by(Prediction_tool) %>% dplyr::summarise(
"Mean"=mean(Statistic_value),
"Standard Deviation"=sd(Statistic_value),
"LowerCI"=CI(Statistic_value)[3],
"UpperCI"=CI(Statistic_value)[1]
)
all.means <- all.class_df.stat %>% dplyr::group_by(Prediction_tool) %>% dplyr::summarise(
"Mean"=mean(Statistic_value),
"Standard Deviation"=sd(Statistic_value),
"LowerCI"=CI(Statistic_value)[3],
"UpperCI"=CI(Statistic_value)[1]
)
all.means$Tax_group <- rep("All", nrow(all.means))
bact.means$Tax_group <- rep("Bacteria", nrow(bact.means))
euk.means$Tax_group <- rep("Eukaryote", nrow(euk.means))
class_df.class.stat.tax <- rbind(all.means, bact.means)
class_df.class.stat.tax <- rbind(class_df.class.stat.tax, euk.means)
class_df.class.stat.tax$Prediction_tool <- factor(class_df.class.stat.tax$Prediction_tool, levels=classifiers_full)
class_df.class.stat.tax$CAZy_class <- rep(cazy_class, nrow(class_df.class.stat.tax))
return(class_df.class.stat.tax)
}
build.class.tax.sum <- function(cazy.class.df, bact.class.df, euk.class.df, stat_param){
# 3 dataframes have the same structure.
# colnames: "X", "Genomic_accession", "Prediction_tool", "CAZy_class", "Statistic_parameter", "Statistic_value"
# auto parse CAZy class GH to produce starting point for the dataframe
class_df.class.stat.tax <- build.class.tax.sum.GH(cazy.class.df, bact.class.df, euk.class.df, stat_param)
for (cazy_class in cazy_class_list){
if (cazy_class == "GH"){next}
else {
class_df.class.stat.tax.class <- build.class.tax.sum.class(cazy.class.df, bact.class.df, euk.class.df, stat_param, cazy_class)
class_df.class.stat.tax <- rbind(class_df.class.stat.tax, class_df.class.stat.tax.class)
}
}
return(class_df.class.stat.tax)
}
| Prediction_tool | Mean | Standard Deviation | LowerCI | UpperCI | Tax_group | CAZy_class |
|---|---|---|---|---|---|---|
| dbCAN_2 | 0.9917 | 0.0245 | 0.9862 | 0.9972 | All | GH |
| dbCAN_2:HMMER | 0.9927 | 0.0242 | 0.9873 | 0.9981 | All | GH |
| dbCAN_2:DIAMOND | 0.9862 | 0.0276 | 0.9801 | 0.9924 | All | GH |
| dbCAN_2:Hotpep | 0.9833 | 0.0286 | 0.9769 | 0.9897 | All | GH |
| dbCAN_3 | 0.9923 | 0.0228 | 0.9873 | 0.9974 | All | GH |
| dbCAN_3:HMMER | 0.9939 | 0.0224 | 0.9889 | 0.9988 | All | GH |
| dbCAN_3:DIAMOND | 0.9844 | 0.0292 | 0.9779 | 0.9909 | All | GH |
| dbCAN_3:eCAMI | 0.9848 | 0.0295 | 0.9782 | 0.9913 | All | GH |
| dbCAN_4 | 0.9927 | 0.0240 | 0.9873 | 0.9980 | All | GH |
| dbCAN_4:HMMER | 0.9939 | 0.0224 | 0.9889 | 0.9988 | All | GH |
| dbCAN_4:DIAMOND | 0.9864 | 0.0279 | 0.9802 | 0.9927 | All | GH |
| dbCAN_4:dbCAN-sub | 0.9924 | 0.0238 | 0.9871 | 0.9977 | All | GH |
| CUPP | 0.9933 | 0.0212 | 0.9886 | 0.9980 | All | GH |
| dbCAN_2 | 0.9932 | 0.0144 | 0.9886 | 0.9978 | Bacteria | GH |
| dbCAN_2:HMMER | 0.9945 | 0.0133 | 0.9902 | 0.9987 | Bacteria | GH |
| dbCAN_2:DIAMOND | 0.9844 | 0.0230 | 0.9770 | 0.9918 | Bacteria | GH |
| dbCAN_2:Hotpep | 0.9753 | 0.0283 | 0.9662 | 0.9843 | Bacteria | GH |
| dbCAN_3 | 0.9932 | 0.0137 | 0.9888 | 0.9975 | Bacteria | GH |
| dbCAN_3:HMMER | 0.9954 | 0.0124 | 0.9914 | 0.9993 | Bacteria | GH |
| dbCAN_3:DIAMOND | 0.9846 | 0.0239 | 0.9769 | 0.9922 | Bacteria | GH |
| dbCAN_3:eCAMI | 0.9794 | 0.0278 | 0.9705 | 0.9883 | Bacteria | GH |
| dbCAN_4 | 0.9933 | 0.0141 | 0.9888 | 0.9978 | Bacteria | GH |
| dbCAN_4:HMMER | 0.9954 | 0.0124 | 0.9914 | 0.9993 | Bacteria | GH |
| dbCAN_4:DIAMOND | 0.9891 | 0.0196 | 0.9829 | 0.9954 | Bacteria | GH |
| dbCAN_4:dbCAN-sub | 0.9927 | 0.0143 | 0.9881 | 0.9973 | Bacteria | GH |
| CUPP | 0.9935 | 0.0140 | 0.9890 | 0.9980 | Bacteria | GH |
| dbCAN_2 | 0.9902 | 0.0318 | 0.9801 | 1.0004 | Eukaryote | GH |
| dbCAN_2:HMMER | 0.9909 | 0.0317 | 0.9808 | 1.0010 | Eukaryote | GH |
| dbCAN_2:DIAMOND | 0.9881 | 0.0318 | 0.9779 | 0.9982 | Eukaryote | GH |
| dbCAN_2:Hotpep | 0.9913 | 0.0269 | 0.9827 | 0.9999 | Eukaryote | GH |
| dbCAN_3 | 0.9915 | 0.0295 | 0.9821 | 1.0009 | Eukaryote | GH |
| dbCAN_3:HMMER | 0.9923 | 0.0293 | 0.9830 | 1.0017 | Eukaryote | GH |
| dbCAN_3:DIAMOND | 0.9843 | 0.0339 | 0.9734 | 0.9951 | Eukaryote | GH |
| dbCAN_3:eCAMI | 0.9901 | 0.0306 | 0.9803 | 0.9998 | Eukaryote | GH |
| dbCAN_4 | 0.9920 | 0.0312 | 0.9821 | 1.0020 | Eukaryote | GH |
| dbCAN_4:HMMER | 0.9923 | 0.0293 | 0.9830 | 1.0017 | Eukaryote | GH |
| dbCAN_4:DIAMOND | 0.9837 | 0.0344 | 0.9727 | 0.9947 | Eukaryote | GH |
| dbCAN_4:dbCAN-sub | 0.9921 | 0.0308 | 0.9823 | 1.0019 | Eukaryote | GH |
| CUPP | 0.9931 | 0.0268 | 0.9845 | 1.0016 | Eukaryote | GH |
| dbCAN_2 | 0.9927 | 0.0454 | 0.9826 | 1.0028 | All | GT |
| dbCAN_2:HMMER | 0.9904 | 0.0487 | 0.9796 | 1.0012 | All | GT |
| dbCAN_2:DIAMOND | 0.9919 | 0.0460 | 0.9817 | 1.0021 | All | GT |
| dbCAN_2:Hotpep | 0.9924 | 0.0421 | 0.9830 | 1.0017 | All | GT |
| dbCAN_3 | 0.9914 | 0.0474 | 0.9808 | 1.0019 | All | GT |
| dbCAN_3:HMMER | 0.9904 | 0.0487 | 0.9796 | 1.0012 | All | GT |
| dbCAN_3:DIAMOND | 0.9893 | 0.0486 | 0.9784 | 1.0001 | All | GT |
| dbCAN_3:eCAMI | 0.9922 | 0.0439 | 0.9824 | 1.0019 | All | GT |
| dbCAN_4 | 0.9900 | 0.0492 | 0.9790 | 1.0009 | All | GT |
| dbCAN_4:HMMER | 0.9904 | 0.0487 | 0.9796 | 1.0012 | All | GT |
| dbCAN_4:DIAMOND | 0.9893 | 0.0488 | 0.9785 | 1.0002 | All | GT |
| dbCAN_4:dbCAN-sub | 0.9900 | 0.0492 | 0.9790 | 1.0009 | All | GT |
| CUPP | 0.9921 | 0.0463 | 0.9818 | 1.0024 | All | GT |
| dbCAN_2 | 0.9991 | 0.0041 | 0.9978 | 1.0004 | Bacteria | GT |
| dbCAN_2:HMMER | 0.9990 | 0.0044 | 0.9976 | 1.0004 | Bacteria | GT |
| dbCAN_2:DIAMOND | 0.9986 | 0.0070 | 0.9963 | 1.0008 | Bacteria | GT |
| dbCAN_2:Hotpep | 0.9976 | 0.0060 | 0.9957 | 0.9995 | Bacteria | GT |
| dbCAN_3 | 0.9991 | 0.0042 | 0.9977 | 1.0004 | Bacteria | GT |
| dbCAN_3:HMMER | 0.9990 | 0.0044 | 0.9976 | 1.0004 | Bacteria | GT |
| dbCAN_3:DIAMOND | 0.9983 | 0.0073 | 0.9959 | 1.0006 | Bacteria | GT |
| dbCAN_3:eCAMI | 0.9976 | 0.0083 | 0.9949 | 1.0003 | Bacteria | GT |
| dbCAN_4 | 0.9987 | 0.0047 | 0.9972 | 1.0002 | Bacteria | GT |
| dbCAN_4:HMMER | 0.9990 | 0.0044 | 0.9976 | 1.0004 | Bacteria | GT |
| dbCAN_4:DIAMOND | 0.9983 | 0.0073 | 0.9959 | 1.0006 | Bacteria | GT |
| dbCAN_4:dbCAN-sub | 0.9987 | 0.0047 | 0.9972 | 1.0002 | Bacteria | GT |
| CUPP | 0.9994 | 0.0039 | 0.9982 | 1.0006 | Bacteria | GT |
| dbCAN_2 | 0.9864 | 0.0638 | 0.9659 | 1.0068 | Eukaryote | GT |
| dbCAN_2:HMMER | 0.9818 | 0.0680 | 0.9600 | 1.0035 | Eukaryote | GT |
| dbCAN_2:DIAMOND | 0.9852 | 0.0644 | 0.9646 | 1.0058 | Eukaryote | GT |
| dbCAN_2:Hotpep | 0.9871 | 0.0592 | 0.9682 | 1.0060 | Eukaryote | GT |
| dbCAN_3 | 0.9837 | 0.0664 | 0.9625 | 1.0050 | Eukaryote | GT |
| dbCAN_3:HMMER | 0.9818 | 0.0680 | 0.9600 | 1.0035 | Eukaryote | GT |
| dbCAN_3:DIAMOND | 0.9803 | 0.0676 | 0.9587 | 1.0019 | Eukaryote | GT |
| dbCAN_3:eCAMI | 0.9867 | 0.0614 | 0.9671 | 1.0064 | Eukaryote | GT |
| dbCAN_4 | 0.9812 | 0.0687 | 0.9592 | 1.0032 | Eukaryote | GT |
| dbCAN_4:HMMER | 0.9818 | 0.0680 | 0.9600 | 1.0035 | Eukaryote | GT |
| dbCAN_4:DIAMOND | 0.9804 | 0.0678 | 0.9587 | 1.0021 | Eukaryote | GT |
| dbCAN_4:dbCAN-sub | 0.9812 | 0.0687 | 0.9592 | 1.0032 | Eukaryote | GT |
| CUPP | 0.9848 | 0.0649 | 0.9640 | 1.0056 | Eukaryote | GT |
| dbCAN_2 | 0.9998 | 0.0012 | 0.9995 | 1.0002 | All | PL |
| dbCAN_2:HMMER | 0.9998 | 0.0012 | 0.9995 | 1.0002 | All | PL |
| dbCAN_2:DIAMOND | 0.9996 | 0.0019 | 0.9991 | 1.0002 | All | PL |
| dbCAN_2:Hotpep | 0.9993 | 0.0027 | 0.9985 | 1.0001 | All | PL |
| dbCAN_3 | 0.9994 | 0.0025 | 0.9986 | 1.0001 | All | PL |
| dbCAN_3:HMMER | 0.9994 | 0.0025 | 0.9986 | 1.0001 | All | PL |
| dbCAN_3:DIAMOND | 0.9989 | 0.0039 | 0.9978 | 1.0000 | All | PL |
| dbCAN_3:eCAMI | 0.9996 | 0.0018 | 0.9991 | 1.0002 | All | PL |
| dbCAN_4 | 0.9994 | 0.0025 | 0.9986 | 1.0001 | All | PL |
| dbCAN_4:HMMER | 0.9994 | 0.0025 | 0.9986 | 1.0001 | All | PL |
| dbCAN_4:DIAMOND | 0.9989 | 0.0039 | 0.9978 | 1.0000 | All | PL |
| dbCAN_4:dbCAN-sub | 0.9994 | 0.0025 | 0.9986 | 1.0001 | All | PL |
| CUPP | 0.9996 | 0.0019 | 0.9990 | 1.0002 | All | PL |
| dbCAN_2 | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | PL |
| dbCAN_2:HMMER | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | PL |
| dbCAN_2:DIAMOND | 0.9997 | 0.0018 | 0.9990 | 1.0003 | Bacteria | PL |
| dbCAN_2:Hotpep | 0.9992 | 0.0030 | 0.9981 | 1.0003 | Bacteria | PL |
| dbCAN_3 | 0.9996 | 0.0021 | 0.9988 | 1.0004 | Bacteria | PL |
| dbCAN_3:HMMER | 0.9996 | 0.0021 | 0.9988 | 1.0004 | Bacteria | PL |
| dbCAN_3:DIAMOND | 0.9993 | 0.0028 | 0.9982 | 1.0003 | Bacteria | PL |
| dbCAN_3:eCAMI | 0.9997 | 0.0017 | 0.9991 | 1.0003 | Bacteria | PL |
| dbCAN_4 | 0.9996 | 0.0021 | 0.9988 | 1.0004 | Bacteria | PL |
| dbCAN_4:HMMER | 0.9996 | 0.0021 | 0.9988 | 1.0004 | Bacteria | PL |
| dbCAN_4:DIAMOND | 0.9993 | 0.0028 | 0.9982 | 1.0003 | Bacteria | PL |
| dbCAN_4:dbCAN-sub | 0.9996 | 0.0021 | 0.9988 | 1.0004 | Bacteria | PL |
| CUPP | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | PL |
| dbCAN_2 | 0.9995 | 0.0021 | 0.9984 | 1.0006 | Eukaryote | PL |
| dbCAN_2:HMMER | 0.9995 | 0.0021 | 0.9984 | 1.0006 | Eukaryote | PL |
| dbCAN_2:DIAMOND | 0.9995 | 0.0021 | 0.9984 | 1.0006 | Eukaryote | PL |
| dbCAN_2:Hotpep | 0.9995 | 0.0021 | 0.9984 | 1.0006 | Eukaryote | PL |
| dbCAN_3 | 0.9989 | 0.0031 | 0.9973 | 1.0005 | Eukaryote | PL |
| dbCAN_3:HMMER | 0.9989 | 0.0031 | 0.9973 | 1.0005 | Eukaryote | PL |
| dbCAN_3:DIAMOND | 0.9982 | 0.0054 | 0.9955 | 1.0010 | Eukaryote | PL |
| dbCAN_3:eCAMI | 0.9995 | 0.0021 | 0.9984 | 1.0006 | Eukaryote | PL |
| dbCAN_4 | 0.9989 | 0.0030 | 0.9974 | 1.0005 | Eukaryote | PL |
| dbCAN_4:HMMER | 0.9989 | 0.0031 | 0.9973 | 1.0005 | Eukaryote | PL |
| dbCAN_4:DIAMOND | 0.9982 | 0.0053 | 0.9955 | 1.0010 | Eukaryote | PL |
| dbCAN_4:dbCAN-sub | 0.9989 | 0.0030 | 0.9974 | 1.0005 | Eukaryote | PL |
| CUPP | 0.9989 | 0.0031 | 0.9973 | 1.0005 | Eukaryote | PL |
| dbCAN_2 | 0.9937 | 0.0220 | 0.9887 | 0.9988 | All | CE |
| dbCAN_2:HMMER | 0.9945 | 0.0187 | 0.9902 | 0.9988 | All | CE |
| dbCAN_2:DIAMOND | 0.9941 | 0.0210 | 0.9893 | 0.9989 | All | CE |
| dbCAN_2:Hotpep | 0.9905 | 0.0229 | 0.9852 | 0.9957 | All | CE |
| dbCAN_3 | 0.9936 | 0.0224 | 0.9885 | 0.9988 | All | CE |
| dbCAN_3:HMMER | 0.9953 | 0.0179 | 0.9912 | 0.9994 | All | CE |
| dbCAN_3:DIAMOND | 0.9925 | 0.0234 | 0.9872 | 0.9979 | All | CE |
| dbCAN_3:eCAMI | 0.9926 | 0.0213 | 0.9877 | 0.9975 | All | CE |
| dbCAN_4 | 0.9953 | 0.0179 | 0.9912 | 0.9994 | All | CE |
| dbCAN_4:HMMER | 0.9953 | 0.0179 | 0.9912 | 0.9994 | All | CE |
| dbCAN_4:DIAMOND | 0.9931 | 0.0227 | 0.9879 | 0.9983 | All | CE |
| dbCAN_4:dbCAN-sub | 0.9952 | 0.0181 | 0.9911 | 0.9993 | All | CE |
| CUPP | 0.9955 | 0.0178 | 0.9914 | 0.9995 | All | CE |
| dbCAN_2 | 0.9886 | 0.0294 | 0.9792 | 0.9980 | Bacteria | CE |
| dbCAN_2:HMMER | 0.9906 | 0.0250 | 0.9826 | 0.9986 | Bacteria | CE |
| dbCAN_2:DIAMOND | 0.9891 | 0.0281 | 0.9801 | 0.9981 | Bacteria | CE |
| dbCAN_2:Hotpep | 0.9829 | 0.0295 | 0.9735 | 0.9924 | Bacteria | CE |
| dbCAN_3 | 0.9884 | 0.0299 | 0.9789 | 0.9980 | Bacteria | CE |
| dbCAN_3:HMMER | 0.9919 | 0.0241 | 0.9842 | 0.9996 | Bacteria | CE |
| dbCAN_3:DIAMOND | 0.9894 | 0.0285 | 0.9803 | 0.9985 | Bacteria | CE |
| dbCAN_3:eCAMI | 0.9862 | 0.0279 | 0.9773 | 0.9951 | Bacteria | CE |
| dbCAN_4 | 0.9919 | 0.0241 | 0.9842 | 0.9996 | Bacteria | CE |
| dbCAN_4:HMMER | 0.9919 | 0.0241 | 0.9842 | 0.9996 | Bacteria | CE |
| dbCAN_4:DIAMOND | 0.9904 | 0.0276 | 0.9816 | 0.9993 | Bacteria | CE |
| dbCAN_4:dbCAN-sub | 0.9919 | 0.0241 | 0.9842 | 0.9996 | Bacteria | CE |
| CUPP | 0.9919 | 0.0239 | 0.9843 | 0.9995 | Bacteria | CE |
| dbCAN_2 | 0.9994 | 0.0035 | 0.9982 | 1.0006 | Eukaryote | CE |
| dbCAN_2:HMMER | 0.9988 | 0.0042 | 0.9974 | 1.0003 | Eukaryote | CE |
| dbCAN_2:DIAMOND | 0.9997 | 0.0018 | 0.9991 | 1.0003 | Eukaryote | CE |
| dbCAN_2:Hotpep | 0.9989 | 0.0042 | 0.9974 | 1.0003 | Eukaryote | CE |
| dbCAN_3 | 0.9994 | 0.0035 | 0.9982 | 1.0006 | Eukaryote | CE |
| dbCAN_3:HMMER | 0.9991 | 0.0039 | 0.9978 | 1.0004 | Eukaryote | CE |
| dbCAN_3:DIAMOND | 0.9960 | 0.0156 | 0.9907 | 1.0013 | Eukaryote | CE |
| dbCAN_3:eCAMI | 0.9997 | 0.0018 | 0.9991 | 1.0003 | Eukaryote | CE |
| dbCAN_4 | 0.9991 | 0.0038 | 0.9978 | 1.0004 | Eukaryote | CE |
| dbCAN_4:HMMER | 0.9991 | 0.0039 | 0.9978 | 1.0004 | Eukaryote | CE |
| dbCAN_4:DIAMOND | 0.9960 | 0.0155 | 0.9908 | 1.0013 | Eukaryote | CE |
| dbCAN_4:dbCAN-sub | 0.9989 | 0.0054 | 0.9970 | 1.0007 | Eukaryote | CE |
| CUPP | 0.9994 | 0.0035 | 0.9982 | 1.0006 | Eukaryote | CE |
| dbCAN_2 | 0.9919 | 0.0178 | 0.9868 | 0.9971 | All | AA |
| dbCAN_2:HMMER | 0.9913 | 0.0187 | 0.9859 | 0.9967 | All | AA |
| dbCAN_2:DIAMOND | 0.9922 | 0.0178 | 0.9870 | 0.9974 | All | AA |
| dbCAN_2:Hotpep | 0.9920 | 0.0180 | 0.9867 | 0.9972 | All | AA |
| dbCAN_3 | 0.9911 | 0.0199 | 0.9853 | 0.9969 | All | AA |
| dbCAN_3:HMMER | 0.9907 | 0.0202 | 0.9848 | 0.9965 | All | AA |
| dbCAN_3:DIAMOND | 0.9900 | 0.0219 | 0.9837 | 0.9964 | All | AA |
| dbCAN_3:eCAMI | 0.9921 | 0.0167 | 0.9873 | 0.9970 | All | AA |
| dbCAN_4 | 0.9907 | 0.0201 | 0.9848 | 0.9965 | All | AA |
| dbCAN_4:HMMER | 0.9907 | 0.0202 | 0.9848 | 0.9965 | All | AA |
| dbCAN_4:DIAMOND | 0.9903 | 0.0219 | 0.9839 | 0.9966 | All | AA |
| dbCAN_4:dbCAN-sub | 0.9905 | 0.0202 | 0.9846 | 0.9963 | All | AA |
| CUPP | 0.9919 | 0.0175 | 0.9868 | 0.9970 | All | AA |
| dbCAN_2 | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_2:HMMER | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_2:DIAMOND | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_2:Hotpep | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_3 | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_3:HMMER | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_3:DIAMOND | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_3:eCAMI | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_4 | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_4:HMMER | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_4:DIAMOND | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_4:dbCAN-sub | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| CUPP | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_2 | 0.9896 | 0.0197 | 0.9830 | 0.9961 | Eukaryote | AA |
| dbCAN_2:HMMER | 0.9887 | 0.0206 | 0.9818 | 0.9956 | Eukaryote | AA |
| dbCAN_2:DIAMOND | 0.9899 | 0.0198 | 0.9833 | 0.9965 | Eukaryote | AA |
| dbCAN_2:Hotpep | 0.9896 | 0.0200 | 0.9829 | 0.9962 | Eukaryote | AA |
| dbCAN_3 | 0.9884 | 0.0220 | 0.9811 | 0.9958 | Eukaryote | AA |
| dbCAN_3:HMMER | 0.9879 | 0.0223 | 0.9804 | 0.9953 | Eukaryote | AA |
| dbCAN_3:DIAMOND | 0.9871 | 0.0242 | 0.9790 | 0.9951 | Eukaryote | AA |
| dbCAN_3:eCAMI | 0.9898 | 0.0184 | 0.9836 | 0.9959 | Eukaryote | AA |
| dbCAN_4 | 0.9879 | 0.0223 | 0.9805 | 0.9953 | Eukaryote | AA |
| dbCAN_4:HMMER | 0.9879 | 0.0223 | 0.9804 | 0.9953 | Eukaryote | AA |
| dbCAN_4:DIAMOND | 0.9874 | 0.0242 | 0.9793 | 0.9954 | Eukaryote | AA |
| dbCAN_4:dbCAN-sub | 0.9876 | 0.0223 | 0.9802 | 0.9951 | Eukaryote | AA |
| CUPP | 0.9895 | 0.0193 | 0.9831 | 0.9960 | Eukaryote | AA |
| dbCAN_2 | 0.9922 | 0.0119 | 0.9896 | 0.9948 | All | CBM |
| dbCAN_2:HMMER | 0.9961 | 0.0088 | 0.9941 | 0.9980 | All | CBM |
| dbCAN_2:DIAMOND | 0.9914 | 0.0149 | 0.9881 | 0.9947 | All | CBM |
| dbCAN_2:Hotpep | 0.9014 | 0.0511 | 0.8901 | 0.9128 | All | CBM |
| dbCAN_3 | 0.9943 | 0.0109 | 0.9919 | 0.9968 | All | CBM |
| dbCAN_3:HMMER | 0.9960 | 0.0088 | 0.9941 | 0.9980 | All | CBM |
| dbCAN_3:DIAMOND | 0.9931 | 0.0144 | 0.9899 | 0.9963 | All | CBM |
| dbCAN_3:eCAMI | 0.9470 | 0.0523 | 0.9354 | 0.9587 | All | CBM |
| dbCAN_4 | 0.9951 | 0.0103 | 0.9928 | 0.9974 | All | CBM |
| dbCAN_4:HMMER | 0.9958 | 0.0097 | 0.9937 | 0.9980 | All | CBM |
| dbCAN_4:DIAMOND | 0.9938 | 0.0146 | 0.9906 | 0.9970 | All | CBM |
| dbCAN_4:dbCAN-sub | 0.9927 | 0.0129 | 0.9898 | 0.9955 | All | CBM |
| CUPP | 1.0000 | 0.0000 | 1.0000 | 1.0000 | All | CBM |
| dbCAN_2 | 0.9947 | 0.0091 | 0.9918 | 0.9976 | Bacteria | CBM |
| dbCAN_2:HMMER | 0.9951 | 0.0106 | 0.9917 | 0.9985 | Bacteria | CBM |
| dbCAN_2:DIAMOND | 0.9942 | 0.0146 | 0.9895 | 0.9988 | Bacteria | CBM |
| dbCAN_2:Hotpep | 0.8917 | 0.0580 | 0.8732 | 0.9103 | Bacteria | CBM |
| dbCAN_3 | 0.9947 | 0.0110 | 0.9912 | 0.9982 | Bacteria | CBM |
| dbCAN_3:HMMER | 0.9951 | 0.0106 | 0.9917 | 0.9985 | Bacteria | CBM |
| dbCAN_3:DIAMOND | 0.9933 | 0.0164 | 0.9880 | 0.9985 | Bacteria | CBM |
| dbCAN_3:eCAMI | 0.9349 | 0.0588 | 0.9161 | 0.9537 | Bacteria | CBM |
| dbCAN_4 | 0.9953 | 0.0106 | 0.9920 | 0.9987 | Bacteria | CBM |
| dbCAN_4:HMMER | 0.9951 | 0.0106 | 0.9917 | 0.9985 | Bacteria | CBM |
| dbCAN_4:DIAMOND | 0.9937 | 0.0154 | 0.9887 | 0.9986 | Bacteria | CBM |
| dbCAN_4:dbCAN-sub | 0.9939 | 0.0113 | 0.9903 | 0.9975 | Bacteria | CBM |
| CUPP | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | CBM |
| dbCAN_2 | 0.9897 | 0.0138 | 0.9853 | 0.9941 | Eukaryote | CBM |
| dbCAN_2:HMMER | 0.9970 | 0.0066 | 0.9949 | 0.9991 | Eukaryote | CBM |
| dbCAN_2:DIAMOND | 0.9886 | 0.0149 | 0.9839 | 0.9934 | Eukaryote | CBM |
| dbCAN_2:Hotpep | 0.9112 | 0.0417 | 0.8978 | 0.9245 | Eukaryote | CBM |
| dbCAN_3 | 0.9940 | 0.0109 | 0.9905 | 0.9975 | Eukaryote | CBM |
| dbCAN_3:HMMER | 0.9970 | 0.0066 | 0.9949 | 0.9991 | Eukaryote | CBM |
| dbCAN_3:DIAMOND | 0.9929 | 0.0123 | 0.9889 | 0.9968 | Eukaryote | CBM |
| dbCAN_3:eCAMI | 0.9591 | 0.0424 | 0.9456 | 0.9727 | Eukaryote | CBM |
| dbCAN_4 | 0.9949 | 0.0102 | 0.9916 | 0.9982 | Eukaryote | CBM |
| dbCAN_4:HMMER | 0.9966 | 0.0087 | 0.9938 | 0.9993 | Eukaryote | CBM |
| dbCAN_4:DIAMOND | 0.9939 | 0.0139 | 0.9895 | 0.9984 | Eukaryote | CBM |
| dbCAN_4:dbCAN-sub | 0.9914 | 0.0144 | 0.9868 | 0.9961 | Eukaryote | CBM |
| CUPP | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Eukaryote | CBM |
## png
## 2
## png
## 2
| Prediction_tool | Mean | Standard Deviation | LowerCI | UpperCI | Tax_group | CAZy_class |
|---|---|---|---|---|---|---|
| dbCAN_2 | 0.9354 | 0.0907 | 0.9152 | 0.9556 | All | GH |
| dbCAN_2:HMMER | 0.9080 | 0.0824 | 0.8896 | 0.9263 | All | GH |
| dbCAN_2:DIAMOND | 0.9379 | 0.1064 | 0.9142 | 0.9615 | All | GH |
| dbCAN_2:Hotpep | 0.8641 | 0.1181 | 0.8378 | 0.8904 | All | GH |
| dbCAN_3 | 0.9567 | 0.0771 | 0.9396 | 0.9739 | All | GH |
| dbCAN_3:HMMER | 0.9198 | 0.0830 | 0.9013 | 0.9383 | All | GH |
| dbCAN_3:DIAMOND | 0.9760 | 0.0673 | 0.9610 | 0.9910 | All | GH |
| dbCAN_3:eCAMI | 0.8764 | 0.1097 | 0.8520 | 0.9008 | All | GH |
| dbCAN_4 | 0.9500 | 0.0802 | 0.9322 | 0.9679 | All | GH |
| dbCAN_4:HMMER | 0.9202 | 0.0828 | 0.9017 | 0.9386 | All | GH |
| dbCAN_4:DIAMOND | 0.9737 | 0.0763 | 0.9567 | 0.9906 | All | GH |
| dbCAN_4:dbCAN-sub | 0.9473 | 0.0789 | 0.9297 | 0.9648 | All | GH |
| CUPP | 0.9080 | 0.0675 | 0.8930 | 0.9230 | All | GH |
| dbCAN_2 | 0.9364 | 0.1023 | 0.9037 | 0.9691 | Bacteria | GH |
| dbCAN_2:HMMER | 0.9117 | 0.1098 | 0.8766 | 0.9469 | Bacteria | GH |
| dbCAN_2:DIAMOND | 0.9342 | 0.1159 | 0.8972 | 0.9713 | Bacteria | GH |
| dbCAN_2:Hotpep | 0.8977 | 0.1006 | 0.8655 | 0.9298 | Bacteria | GH |
| dbCAN_3 | 0.9597 | 0.1006 | 0.9275 | 0.9919 | Bacteria | GH |
| dbCAN_3:HMMER | 0.9166 | 0.1118 | 0.8808 | 0.9524 | Bacteria | GH |
| dbCAN_3:DIAMOND | 0.9649 | 0.0900 | 0.9361 | 0.9936 | Bacteria | GH |
| dbCAN_3:eCAMI | 0.9142 | 0.1063 | 0.8802 | 0.9482 | Bacteria | GH |
| dbCAN_4 | 0.9534 | 0.1089 | 0.9186 | 0.9882 | Bacteria | GH |
| dbCAN_4:HMMER | 0.9173 | 0.1116 | 0.8816 | 0.9530 | Bacteria | GH |
| dbCAN_4:DIAMOND | 0.9588 | 0.1047 | 0.9253 | 0.9923 | Bacteria | GH |
| dbCAN_4:dbCAN-sub | 0.9549 | 0.1056 | 0.9211 | 0.9887 | Bacteria | GH |
| CUPP | 0.9170 | 0.0792 | 0.8917 | 0.9423 | Bacteria | GH |
| dbCAN_2 | 0.9343 | 0.0788 | 0.9091 | 0.9595 | Eukaryote | GH |
| dbCAN_2:HMMER | 0.9042 | 0.0411 | 0.8911 | 0.9173 | Eukaryote | GH |
| dbCAN_2:DIAMOND | 0.9415 | 0.0973 | 0.9104 | 0.9726 | Eukaryote | GH |
| dbCAN_2:Hotpep | 0.8305 | 0.1257 | 0.7903 | 0.8707 | Eukaryote | GH |
| dbCAN_3 | 0.9538 | 0.0435 | 0.9398 | 0.9677 | Eukaryote | GH |
| dbCAN_3:HMMER | 0.9230 | 0.0375 | 0.9110 | 0.9350 | Eukaryote | GH |
| dbCAN_3:DIAMOND | 0.9872 | 0.0290 | 0.9779 | 0.9964 | Eukaryote | GH |
| dbCAN_3:eCAMI | 0.8385 | 0.1007 | 0.8063 | 0.8708 | Eukaryote | GH |
| dbCAN_4 | 0.9467 | 0.0341 | 0.9358 | 0.9576 | Eukaryote | GH |
| dbCAN_4:HMMER | 0.9230 | 0.0375 | 0.9110 | 0.9350 | Eukaryote | GH |
| dbCAN_4:DIAMOND | 0.9885 | 0.0193 | 0.9823 | 0.9947 | Eukaryote | GH |
| dbCAN_4:dbCAN-sub | 0.9396 | 0.0363 | 0.9280 | 0.9512 | Eukaryote | GH |
| CUPP | 0.8990 | 0.0527 | 0.8821 | 0.9159 | Eukaryote | GH |
| dbCAN_2 | 0.8845 | 0.1378 | 0.8538 | 0.9152 | All | GT |
| dbCAN_2:HMMER | 0.8627 | 0.1126 | 0.8376 | 0.8877 | All | GT |
| dbCAN_2:DIAMOND | 0.9255 | 0.1508 | 0.8919 | 0.9591 | All | GT |
| dbCAN_2:Hotpep | 0.7254 | 0.1807 | 0.6852 | 0.7656 | All | GT |
| dbCAN_3 | 0.9421 | 0.0971 | 0.9205 | 0.9637 | All | GT |
| dbCAN_3:HMMER | 0.8654 | 0.1113 | 0.8406 | 0.8901 | All | GT |
| dbCAN_3:DIAMOND | 0.9774 | 0.0897 | 0.9574 | 0.9973 | All | GT |
| dbCAN_3:eCAMI | 0.8500 | 0.1524 | 0.8161 | 0.8839 | All | GT |
| dbCAN_4 | 0.9578 | 0.0921 | 0.9373 | 0.9783 | All | GT |
| dbCAN_4:HMMER | 0.8657 | 0.1110 | 0.8410 | 0.8904 | All | GT |
| dbCAN_4:DIAMOND | 0.9751 | 0.0914 | 0.9548 | 0.9954 | All | GT |
| dbCAN_4:dbCAN-sub | 0.9538 | 0.0835 | 0.9352 | 0.9724 | All | GT |
| CUPP | 0.8536 | 0.1107 | 0.8289 | 0.8782 | All | GT |
| dbCAN_2 | 0.8819 | 0.1395 | 0.8373 | 0.9265 | Bacteria | GT |
| dbCAN_2:HMMER | 0.8491 | 0.1312 | 0.8071 | 0.8910 | Bacteria | GT |
| dbCAN_2:DIAMOND | 0.9240 | 0.1583 | 0.8733 | 0.9746 | Bacteria | GT |
| dbCAN_2:Hotpep | 0.6785 | 0.1870 | 0.6187 | 0.7383 | Bacteria | GT |
| dbCAN_3 | 0.9324 | 0.1249 | 0.8924 | 0.9723 | Bacteria | GT |
| dbCAN_3:HMMER | 0.8482 | 0.1301 | 0.8066 | 0.8898 | Bacteria | GT |
| dbCAN_3:DIAMOND | 0.9658 | 0.1219 | 0.9268 | 1.0048 | Bacteria | GT |
| dbCAN_3:eCAMI | 0.8549 | 0.1621 | 0.8030 | 0.9067 | Bacteria | GT |
| dbCAN_4 | 0.9448 | 0.1259 | 0.9046 | 0.9851 | Bacteria | GT |
| dbCAN_4:HMMER | 0.8493 | 0.1301 | 0.8077 | 0.8909 | Bacteria | GT |
| dbCAN_4:DIAMOND | 0.9546 | 0.1262 | 0.9142 | 0.9949 | Bacteria | GT |
| dbCAN_4:dbCAN-sub | 0.9445 | 0.1117 | 0.9088 | 0.9802 | Bacteria | GT |
| CUPP | 0.8754 | 0.1137 | 0.8391 | 0.9118 | Bacteria | GT |
| dbCAN_2 | 0.8871 | 0.1379 | 0.8430 | 0.9312 | Eukaryote | GT |
| dbCAN_2:HMMER | 0.8762 | 0.0901 | 0.8474 | 0.9051 | Eukaryote | GT |
| dbCAN_2:DIAMOND | 0.9271 | 0.1449 | 0.8807 | 0.9734 | Eukaryote | GT |
| dbCAN_2:Hotpep | 0.7723 | 0.1633 | 0.7201 | 0.8246 | Eukaryote | GT |
| dbCAN_3 | 0.9519 | 0.0576 | 0.9334 | 0.9703 | Eukaryote | GT |
| dbCAN_3:HMMER | 0.8825 | 0.0870 | 0.8547 | 0.9103 | Eukaryote | GT |
| dbCAN_3:DIAMOND | 0.9890 | 0.0339 | 0.9782 | 0.9998 | Eukaryote | GT |
| dbCAN_3:eCAMI | 0.8451 | 0.1440 | 0.7991 | 0.8912 | Eukaryote | GT |
| dbCAN_4 | 0.9708 | 0.0317 | 0.9607 | 0.9809 | Eukaryote | GT |
| dbCAN_4:HMMER | 0.8821 | 0.0866 | 0.8544 | 0.9098 | Eukaryote | GT |
| dbCAN_4:DIAMOND | 0.9956 | 0.0118 | 0.9919 | 0.9994 | Eukaryote | GT |
| dbCAN_4:dbCAN-sub | 0.9631 | 0.0384 | 0.9508 | 0.9754 | Eukaryote | GT |
| CUPP | 0.8317 | 0.1045 | 0.7983 | 0.8651 | Eukaryote | GT |
| dbCAN_2 | 0.8797 | 0.2421 | 0.8086 | 0.9508 | All | PL |
| dbCAN_2:HMMER | 0.8975 | 0.2125 | 0.8351 | 0.9598 | All | PL |
| dbCAN_2:DIAMOND | 0.8691 | 0.2687 | 0.7902 | 0.9480 | All | PL |
| dbCAN_2:Hotpep | 0.8407 | 0.2581 | 0.7650 | 0.9165 | All | PL |
| dbCAN_3 | 0.9881 | 0.0732 | 0.9666 | 1.0096 | All | PL |
| dbCAN_3:HMMER | 0.9739 | 0.0982 | 0.9451 | 1.0028 | All | PL |
| dbCAN_3:DIAMOND | 0.9881 | 0.0732 | 0.9666 | 1.0096 | All | PL |
| dbCAN_3:eCAMI | 0.7960 | 0.2776 | 0.7154 | 0.8766 | All | PL |
| dbCAN_4 | 0.9739 | 0.0982 | 0.9451 | 1.0028 | All | PL |
| dbCAN_4:HMMER | 0.9739 | 0.0982 | 0.9451 | 1.0028 | All | PL |
| dbCAN_4:DIAMOND | 0.9987 | 0.0086 | 0.9962 | 1.0013 | All | PL |
| dbCAN_4:dbCAN-sub | 0.9752 | 0.0982 | 0.9464 | 1.0040 | All | PL |
| CUPP | 0.8511 | 0.2593 | 0.7749 | 0.9272 | All | PL |
| dbCAN_2 | 0.9099 | 0.2101 | 0.8314 | 0.9884 | Bacteria | PL |
| dbCAN_2:HMMER | 0.9210 | 0.1641 | 0.8597 | 0.9823 | Bacteria | PL |
| dbCAN_2:DIAMOND | 0.9266 | 0.1958 | 0.8534 | 0.9997 | Bacteria | PL |
| dbCAN_2:Hotpep | 0.8738 | 0.1959 | 0.8007 | 0.9470 | Bacteria | PL |
| dbCAN_3 | 0.9814 | 0.0915 | 0.9472 | 1.0156 | Bacteria | PL |
| dbCAN_3:HMMER | 0.9592 | 0.1211 | 0.9139 | 1.0044 | Bacteria | PL |
| dbCAN_3:DIAMOND | 0.9980 | 0.0107 | 0.9940 | 1.0020 | Bacteria | PL |
| dbCAN_3:eCAMI | 0.8181 | 0.2466 | 0.7276 | 0.9085 | Bacteria | PL |
| dbCAN_4 | 0.9592 | 0.1211 | 0.9139 | 1.0044 | Bacteria | PL |
| dbCAN_4:HMMER | 0.9592 | 0.1211 | 0.9139 | 1.0044 | Bacteria | PL |
| dbCAN_4:DIAMOND | 0.9980 | 0.0107 | 0.9940 | 1.0020 | Bacteria | PL |
| dbCAN_4:dbCAN-sub | 0.9611 | 0.1213 | 0.9158 | 1.0064 | Bacteria | PL |
| CUPP | 0.8484 | 0.2520 | 0.7542 | 0.9425 | Bacteria | PL |
| dbCAN_2 | 0.8265 | 0.2895 | 0.6776 | 0.9753 | Eukaryote | PL |
| dbCAN_2:HMMER | 0.8559 | 0.2794 | 0.7122 | 0.9996 | Eukaryote | PL |
| dbCAN_2:DIAMOND | 0.7676 | 0.3477 | 0.5889 | 0.9464 | Eukaryote | PL |
| dbCAN_2:Hotpep | 0.7824 | 0.3409 | 0.6071 | 0.9576 | Eukaryote | PL |
| dbCAN_3 | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Eukaryote | PL |
| dbCAN_3:HMMER | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Eukaryote | PL |
| dbCAN_3:DIAMOND | 0.9706 | 0.1213 | 0.9082 | 1.0329 | Eukaryote | PL |
| dbCAN_3:eCAMI | 0.7559 | 0.3311 | 0.5856 | 0.9261 | Eukaryote | PL |
| dbCAN_4 | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Eukaryote | PL |
| dbCAN_4:HMMER | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Eukaryote | PL |
| dbCAN_4:DIAMOND | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Eukaryote | PL |
| dbCAN_4:dbCAN-sub | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Eukaryote | PL |
| CUPP | 0.8559 | 0.2794 | 0.7122 | 0.9996 | Eukaryote | PL |
| dbCAN_2 | 0.9213 | 0.1433 | 0.8886 | 0.9540 | All | CE |
| dbCAN_2:HMMER | 0.9208 | 0.1363 | 0.8896 | 0.9519 | All | CE |
| dbCAN_2:DIAMOND | 0.8480 | 0.2469 | 0.7915 | 0.9044 | All | CE |
| dbCAN_2:Hotpep | 0.8508 | 0.2065 | 0.8036 | 0.8980 | All | CE |
| dbCAN_3 | 0.9283 | 0.1537 | 0.8932 | 0.9634 | All | CE |
| dbCAN_3:HMMER | 0.9230 | 0.1335 | 0.8925 | 0.9535 | All | CE |
| dbCAN_3:DIAMOND | 0.9303 | 0.1704 | 0.8913 | 0.9692 | All | CE |
| dbCAN_3:eCAMI | 0.8073 | 0.2445 | 0.7514 | 0.8632 | All | CE |
| dbCAN_4 | 0.9783 | 0.0669 | 0.9630 | 0.9935 | All | CE |
| dbCAN_4:HMMER | 0.9529 | 0.1012 | 0.9298 | 0.9760 | All | CE |
| dbCAN_4:DIAMOND | 0.9755 | 0.0851 | 0.9560 | 0.9949 | All | CE |
| dbCAN_4:dbCAN-sub | 0.9755 | 0.0680 | 0.9599 | 0.9910 | All | CE |
| CUPP | 0.9114 | 0.1332 | 0.8810 | 0.9419 | All | CE |
| dbCAN_2 | 0.9296 | 0.1184 | 0.8917 | 0.9675 | Bacteria | CE |
| dbCAN_2:HMMER | 0.8801 | 0.1503 | 0.8320 | 0.9282 | Bacteria | CE |
| dbCAN_2:DIAMOND | 0.8797 | 0.1688 | 0.8257 | 0.9337 | Bacteria | CE |
| dbCAN_2:Hotpep | 0.9226 | 0.1251 | 0.8826 | 0.9627 | Bacteria | CE |
| dbCAN_3 | 0.9210 | 0.1569 | 0.8708 | 0.9712 | Bacteria | CE |
| dbCAN_3:HMMER | 0.8801 | 0.1503 | 0.8320 | 0.9282 | Bacteria | CE |
| dbCAN_3:DIAMOND | 0.9342 | 0.1346 | 0.8911 | 0.9772 | Bacteria | CE |
| dbCAN_3:eCAMI | 0.8639 | 0.1908 | 0.8029 | 0.9250 | Bacteria | CE |
| dbCAN_4 | 0.9670 | 0.0836 | 0.9403 | 0.9937 | Bacteria | CE |
| dbCAN_4:HMMER | 0.9245 | 0.1269 | 0.8839 | 0.9650 | Bacteria | CE |
| dbCAN_4:DIAMOND | 0.9618 | 0.1104 | 0.9265 | 0.9971 | Bacteria | CE |
| dbCAN_4:dbCAN-sub | 0.9634 | 0.0852 | 0.9362 | 0.9907 | Bacteria | CE |
| CUPP | 0.8983 | 0.1322 | 0.8560 | 0.9405 | Bacteria | CE |
| dbCAN_2 | 0.9120 | 0.1679 | 0.8552 | 0.9689 | Eukaryote | CE |
| dbCAN_2:HMMER | 0.9660 | 0.1032 | 0.9311 | 1.0009 | Eukaryote | CE |
| dbCAN_2:DIAMOND | 0.8127 | 0.3106 | 0.7076 | 0.9178 | Eukaryote | CE |
| dbCAN_2:Hotpep | 0.7710 | 0.2479 | 0.6871 | 0.8549 | Eukaryote | CE |
| dbCAN_3 | 0.9363 | 0.1518 | 0.8850 | 0.9877 | Eukaryote | CE |
| dbCAN_3:HMMER | 0.9706 | 0.0926 | 0.9393 | 1.0019 | Eukaryote | CE |
| dbCAN_3:DIAMOND | 0.9259 | 0.2049 | 0.8566 | 0.9952 | Eukaryote | CE |
| dbCAN_3:eCAMI | 0.7444 | 0.2825 | 0.6488 | 0.8400 | Eukaryote | CE |
| dbCAN_4 | 0.9907 | 0.0387 | 0.9776 | 1.0038 | Eukaryote | CE |
| dbCAN_4:HMMER | 0.9845 | 0.0455 | 0.9691 | 0.9999 | Eukaryote | CE |
| dbCAN_4:DIAMOND | 0.9907 | 0.0387 | 0.9776 | 1.0038 | Eukaryote | CE |
| dbCAN_4:dbCAN-sub | 0.9888 | 0.0383 | 0.9759 | 1.0018 | Eukaryote | CE |
| CUPP | 0.9260 | 0.1346 | 0.8805 | 0.9716 | Eukaryote | CE |
| dbCAN_2 | 0.9190 | 0.1152 | 0.8855 | 0.9524 | All | AA |
| dbCAN_2:HMMER | 0.9375 | 0.0917 | 0.9109 | 0.9641 | All | AA |
| dbCAN_2:DIAMOND | 0.8693 | 0.1786 | 0.8174 | 0.9212 | All | AA |
| dbCAN_2:Hotpep | 0.8737 | 0.1942 | 0.8173 | 0.9301 | All | AA |
| dbCAN_3 | 0.9835 | 0.0450 | 0.9705 | 0.9966 | All | AA |
| dbCAN_3:HMMER | 0.9880 | 0.0393 | 0.9766 | 0.9994 | All | AA |
| dbCAN_3:DIAMOND | 0.9884 | 0.0359 | 0.9779 | 0.9988 | All | AA |
| dbCAN_3:eCAMI | 0.7821 | 0.2611 | 0.7063 | 0.8579 | All | AA |
| dbCAN_4 | 0.9937 | 0.0258 | 0.9862 | 1.0012 | All | AA |
| dbCAN_4:HMMER | 0.9880 | 0.0393 | 0.9766 | 0.9994 | All | AA |
| dbCAN_4:DIAMOND | 0.9700 | 0.0952 | 0.9423 | 0.9976 | All | AA |
| dbCAN_4:dbCAN-sub | 0.9892 | 0.0331 | 0.9796 | 0.9988 | All | AA |
| CUPP | 0.9047 | 0.1300 | 0.8670 | 0.9425 | All | AA |
| dbCAN_2 | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_2:HMMER | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_2:DIAMOND | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_2:Hotpep | 0.9091 | 0.3015 | 0.7065 | 1.1116 | Bacteria | AA |
| dbCAN_3 | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_3:HMMER | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_3:DIAMOND | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_3:eCAMI | 0.9091 | 0.3015 | 0.7065 | 1.1116 | Bacteria | AA |
| dbCAN_4 | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_4:HMMER | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_4:DIAMOND | 0.9545 | 0.1508 | 0.8533 | 1.0558 | Bacteria | AA |
| dbCAN_4:dbCAN-sub | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| CUPP | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_2 | 0.8949 | 0.1214 | 0.8544 | 0.9354 | Eukaryote | AA |
| dbCAN_2:HMMER | 0.9189 | 0.0971 | 0.8865 | 0.9513 | Eukaryote | AA |
| dbCAN_2:DIAMOND | 0.8305 | 0.1868 | 0.7682 | 0.8927 | Eukaryote | AA |
| dbCAN_2:Hotpep | 0.8632 | 0.1533 | 0.8121 | 0.9143 | Eukaryote | AA |
| dbCAN_3 | 0.9786 | 0.0503 | 0.9619 | 0.9954 | Eukaryote | AA |
| dbCAN_3:HMMER | 0.9844 | 0.0442 | 0.9697 | 0.9992 | Eukaryote | AA |
| dbCAN_3:DIAMOND | 0.9849 | 0.0403 | 0.9715 | 0.9983 | Eukaryote | AA |
| dbCAN_3:eCAMI | 0.7443 | 0.2395 | 0.6645 | 0.8242 | Eukaryote | AA |
| dbCAN_4 | 0.9918 | 0.0292 | 0.9821 | 1.0016 | Eukaryote | AA |
| dbCAN_4:HMMER | 0.9844 | 0.0442 | 0.9697 | 0.9992 | Eukaryote | AA |
| dbCAN_4:DIAMOND | 0.9746 | 0.0737 | 0.9500 | 0.9992 | Eukaryote | AA |
| dbCAN_4:dbCAN-sub | 0.9860 | 0.0372 | 0.9736 | 0.9984 | Eukaryote | AA |
| CUPP | 0.8764 | 0.1359 | 0.8311 | 0.9217 | Eukaryote | AA |
| dbCAN_2 | 0.7242 | 0.1925 | 0.6813 | 0.7670 | All | CBM |
| dbCAN_2:HMMER | 0.4129 | 0.2165 | 0.3648 | 0.4611 | All | CBM |
| dbCAN_2:DIAMOND | 0.7854 | 0.2191 | 0.7367 | 0.8342 | All | CBM |
| dbCAN_2:Hotpep | 0.7061 | 0.2102 | 0.6594 | 0.7529 | All | CBM |
| dbCAN_3 | 0.7680 | 0.1926 | 0.7252 | 0.8109 | All | CBM |
| dbCAN_3:HMMER | 0.4135 | 0.2148 | 0.3657 | 0.4613 | All | CBM |
| dbCAN_3:DIAMOND | 0.8675 | 0.1731 | 0.8290 | 0.9060 | All | CBM |
| dbCAN_3:eCAMI | 0.7346 | 0.2203 | 0.6856 | 0.7836 | All | CBM |
| dbCAN_4 | 0.7995 | 0.1921 | 0.7567 | 0.8422 | All | CBM |
| dbCAN_4:HMMER | 0.4740 | 0.2360 | 0.4215 | 0.5266 | All | CBM |
| dbCAN_4:DIAMOND | 0.8773 | 0.1695 | 0.8396 | 0.9151 | All | CBM |
| dbCAN_4:dbCAN-sub | 0.8193 | 0.1995 | 0.7749 | 0.8637 | All | CBM |
| CUPP | 0.0000 | 0.0000 | 0.0000 | 0.0000 | All | CBM |
| dbCAN_2 | 0.7317 | 0.2003 | 0.6676 | 0.7957 | Bacteria | CBM |
| dbCAN_2:HMMER | 0.5107 | 0.2276 | 0.4379 | 0.5834 | Bacteria | CBM |
| dbCAN_2:DIAMOND | 0.7590 | 0.2212 | 0.6883 | 0.8297 | Bacteria | CBM |
| dbCAN_2:Hotpep | 0.7044 | 0.2472 | 0.6253 | 0.7835 | Bacteria | CBM |
| dbCAN_3 | 0.7630 | 0.2112 | 0.6954 | 0.8305 | Bacteria | CBM |
| dbCAN_3:HMMER | 0.5092 | 0.2267 | 0.4367 | 0.5817 | Bacteria | CBM |
| dbCAN_3:DIAMOND | 0.8023 | 0.1976 | 0.7391 | 0.8654 | Bacteria | CBM |
| dbCAN_3:eCAMI | 0.7427 | 0.2415 | 0.6655 | 0.8199 | Bacteria | CBM |
| dbCAN_4 | 0.9025 | 0.1017 | 0.8699 | 0.9350 | Bacteria | CBM |
| dbCAN_4:HMMER | 0.6086 | 0.2286 | 0.5355 | 0.6817 | Bacteria | CBM |
| dbCAN_4:DIAMOND | 0.7955 | 0.1993 | 0.7318 | 0.8592 | Bacteria | CBM |
| dbCAN_4:dbCAN-sub | 0.9441 | 0.0985 | 0.9126 | 0.9756 | Bacteria | CBM |
| CUPP | 0.0000 | 0.0000 | 0.0000 | 0.0000 | Bacteria | CBM |
| dbCAN_2 | 0.7167 | 0.1866 | 0.6570 | 0.7763 | Eukaryote | CBM |
| dbCAN_2:HMMER | 0.3152 | 0.1537 | 0.2661 | 0.3644 | Eukaryote | CBM |
| dbCAN_2:DIAMOND | 0.8119 | 0.2166 | 0.7426 | 0.8811 | Eukaryote | CBM |
| dbCAN_2:Hotpep | 0.7079 | 0.1684 | 0.6540 | 0.7617 | Eukaryote | CBM |
| dbCAN_3 | 0.7730 | 0.1746 | 0.7172 | 0.8289 | Eukaryote | CBM |
| dbCAN_3:HMMER | 0.3177 | 0.1525 | 0.2690 | 0.3665 | Eukaryote | CBM |
| dbCAN_3:DIAMOND | 0.9327 | 0.1137 | 0.8964 | 0.9691 | Eukaryote | CBM |
| dbCAN_3:eCAMI | 0.7264 | 0.1996 | 0.6626 | 0.7903 | Eukaryote | CBM |
| dbCAN_4 | 0.6965 | 0.2066 | 0.6305 | 0.7626 | Eukaryote | CBM |
| dbCAN_4:HMMER | 0.3395 | 0.1530 | 0.2906 | 0.3884 | Eukaryote | CBM |
| dbCAN_4:DIAMOND | 0.9592 | 0.0692 | 0.9370 | 0.9813 | Eukaryote | CBM |
| dbCAN_4:dbCAN-sub | 0.6945 | 0.1974 | 0.6314 | 0.7577 | Eukaryote | CBM |
| CUPP | 0.0000 | 0.0000 | 0.0000 | 0.0000 | Eukaryote | CBM |
## png
## 2
## png
## 2
| Prediction_tool | Mean | Standard Deviation | LowerCI | UpperCI | Tax_group | CAZy_class |
|---|---|---|---|---|---|---|
| dbCAN_2 | 0.9886 | 0.0347 | 0.9809 | 0.9963 | All | GH |
| dbCAN_2:HMMER | 0.9897 | 0.0339 | 0.9821 | 0.9972 | All | GH |
| dbCAN_2:DIAMOND | 0.9845 | 0.0360 | 0.9765 | 0.9926 | All | GH |
| dbCAN_2:Hotpep | 0.9796 | 0.0419 | 0.9702 | 0.9889 | All | GH |
| dbCAN_3 | 0.9897 | 0.0332 | 0.9823 | 0.9971 | All | GH |
| dbCAN_3:HMMER | 0.9909 | 0.0330 | 0.9836 | 0.9983 | All | GH |
| dbCAN_3:DIAMOND | 0.9830 | 0.0391 | 0.9743 | 0.9917 | All | GH |
| dbCAN_3:eCAMI | 0.9829 | 0.0395 | 0.9741 | 0.9917 | All | GH |
| dbCAN_4 | 0.9898 | 0.0337 | 0.9823 | 0.9973 | All | GH |
| dbCAN_4:HMMER | 0.9909 | 0.0330 | 0.9836 | 0.9983 | All | GH |
| dbCAN_4:DIAMOND | 0.9842 | 0.0393 | 0.9754 | 0.9929 | All | GH |
| dbCAN_4:dbCAN-sub | 0.9896 | 0.0337 | 0.9821 | 0.9971 | All | GH |
| CUPP | 0.9906 | 0.0338 | 0.9831 | 0.9981 | All | GH |
| dbCAN_2 | 0.9908 | 0.0219 | 0.9838 | 0.9978 | Bacteria | GH |
| dbCAN_2:HMMER | 0.9935 | 0.0153 | 0.9886 | 0.9984 | Bacteria | GH |
| dbCAN_2:DIAMOND | 0.9841 | 0.0265 | 0.9757 | 0.9926 | Bacteria | GH |
| dbCAN_2:Hotpep | 0.9736 | 0.0369 | 0.9618 | 0.9854 | Bacteria | GH |
| dbCAN_3 | 0.9917 | 0.0191 | 0.9856 | 0.9978 | Bacteria | GH |
| dbCAN_3:HMMER | 0.9945 | 0.0142 | 0.9900 | 0.9991 | Bacteria | GH |
| dbCAN_3:DIAMOND | 0.9858 | 0.0247 | 0.9779 | 0.9937 | Bacteria | GH |
| dbCAN_3:eCAMI | 0.9805 | 0.0274 | 0.9718 | 0.9893 | Bacteria | GH |
| dbCAN_4 | 0.9923 | 0.0176 | 0.9867 | 0.9980 | Bacteria | GH |
| dbCAN_4:HMMER | 0.9945 | 0.0142 | 0.9900 | 0.9991 | Bacteria | GH |
| dbCAN_4:DIAMOND | 0.9886 | 0.0244 | 0.9808 | 0.9964 | Bacteria | GH |
| dbCAN_4:dbCAN-sub | 0.9920 | 0.0175 | 0.9864 | 0.9976 | Bacteria | GH |
| CUPP | 0.9931 | 0.0143 | 0.9886 | 0.9977 | Bacteria | GH |
| dbCAN_2 | 0.9863 | 0.0442 | 0.9722 | 1.0005 | Eukaryote | GH |
| dbCAN_2:HMMER | 0.9859 | 0.0454 | 0.9714 | 1.0004 | Eukaryote | GH |
| dbCAN_2:DIAMOND | 0.9850 | 0.0439 | 0.9709 | 0.9990 | Eukaryote | GH |
| dbCAN_2:Hotpep | 0.9855 | 0.0461 | 0.9708 | 1.0003 | Eukaryote | GH |
| dbCAN_3 | 0.9877 | 0.0432 | 0.9739 | 1.0015 | Eukaryote | GH |
| dbCAN_3:HMMER | 0.9873 | 0.0444 | 0.9731 | 1.0015 | Eukaryote | GH |
| dbCAN_3:DIAMOND | 0.9801 | 0.0497 | 0.9642 | 0.9960 | Eukaryote | GH |
| dbCAN_3:eCAMI | 0.9852 | 0.0489 | 0.9695 | 1.0008 | Eukaryote | GH |
| dbCAN_4 | 0.9873 | 0.0445 | 0.9730 | 1.0015 | Eukaryote | GH |
| dbCAN_4:HMMER | 0.9873 | 0.0444 | 0.9731 | 1.0015 | Eukaryote | GH |
| dbCAN_4:DIAMOND | 0.9797 | 0.0499 | 0.9638 | 0.9957 | Eukaryote | GH |
| dbCAN_4:dbCAN-sub | 0.9872 | 0.0445 | 0.9730 | 1.0015 | Eukaryote | GH |
| CUPP | 0.9880 | 0.0458 | 0.9734 | 1.0027 | Eukaryote | GH |
| dbCAN_2 | 0.9898 | 0.0542 | 0.9778 | 1.0019 | All | GT |
| dbCAN_2:HMMER | 0.9884 | 0.0566 | 0.9758 | 1.0010 | All | GT |
| dbCAN_2:DIAMOND | 0.9886 | 0.0567 | 0.9760 | 1.0013 | All | GT |
| dbCAN_2:Hotpep | 0.9836 | 0.0688 | 0.9683 | 0.9989 | All | GT |
| dbCAN_3 | 0.9891 | 0.0563 | 0.9766 | 1.0016 | All | GT |
| dbCAN_3:HMMER | 0.9884 | 0.0566 | 0.9758 | 1.0010 | All | GT |
| dbCAN_3:DIAMOND | 0.9839 | 0.0620 | 0.9701 | 0.9977 | All | GT |
| dbCAN_3:eCAMI | 0.9881 | 0.0572 | 0.9754 | 1.0009 | All | GT |
| dbCAN_4 | 0.9866 | 0.0566 | 0.9740 | 0.9992 | All | GT |
| dbCAN_4:HMMER | 0.9884 | 0.0566 | 0.9758 | 1.0010 | All | GT |
| dbCAN_4:DIAMOND | 0.9841 | 0.0638 | 0.9699 | 0.9983 | All | GT |
| dbCAN_4:dbCAN-sub | 0.9866 | 0.0566 | 0.9740 | 0.9992 | All | GT |
| CUPP | 0.9883 | 0.0625 | 0.9744 | 1.0022 | All | GT |
| dbCAN_2 | 0.9987 | 0.0058 | 0.9969 | 1.0006 | Bacteria | GT |
| dbCAN_2:HMMER | 0.9988 | 0.0055 | 0.9970 | 1.0005 | Bacteria | GT |
| dbCAN_2:DIAMOND | 0.9984 | 0.0069 | 0.9962 | 1.0007 | Bacteria | GT |
| dbCAN_2:Hotpep | 0.9908 | 0.0250 | 0.9828 | 0.9988 | Bacteria | GT |
| dbCAN_3 | 0.9988 | 0.0053 | 0.9971 | 1.0005 | Bacteria | GT |
| dbCAN_3:HMMER | 0.9988 | 0.0054 | 0.9971 | 1.0005 | Bacteria | GT |
| dbCAN_3:DIAMOND | 0.9975 | 0.0088 | 0.9947 | 1.0004 | Bacteria | GT |
| dbCAN_3:eCAMI | 0.9963 | 0.0112 | 0.9928 | 0.9999 | Bacteria | GT |
| dbCAN_4 | 0.9980 | 0.0074 | 0.9957 | 1.0004 | Bacteria | GT |
| dbCAN_4:HMMER | 0.9988 | 0.0054 | 0.9971 | 1.0005 | Bacteria | GT |
| dbCAN_4:DIAMOND | 0.9975 | 0.0091 | 0.9945 | 1.0004 | Bacteria | GT |
| dbCAN_4:dbCAN-sub | 0.9980 | 0.0074 | 0.9957 | 1.0004 | Bacteria | GT |
| CUPP | 0.9995 | 0.0030 | 0.9985 | 1.0005 | Bacteria | GT |
| dbCAN_2 | 0.9810 | 0.0759 | 0.9567 | 1.0052 | Eukaryote | GT |
| dbCAN_2:HMMER | 0.9781 | 0.0790 | 0.9528 | 1.0033 | Eukaryote | GT |
| dbCAN_2:DIAMOND | 0.9788 | 0.0792 | 0.9535 | 1.0042 | Eukaryote | GT |
| dbCAN_2:Hotpep | 0.9764 | 0.0942 | 0.9463 | 1.0066 | Eukaryote | GT |
| dbCAN_3 | 0.9794 | 0.0787 | 0.9542 | 1.0045 | Eukaryote | GT |
| dbCAN_3:HMMER | 0.9781 | 0.0790 | 0.9528 | 1.0033 | Eukaryote | GT |
| dbCAN_3:DIAMOND | 0.9702 | 0.0856 | 0.9429 | 0.9976 | Eukaryote | GT |
| dbCAN_3:eCAMI | 0.9799 | 0.0798 | 0.9544 | 1.0054 | Eukaryote | GT |
| dbCAN_4 | 0.9752 | 0.0785 | 0.9501 | 1.0003 | Eukaryote | GT |
| dbCAN_4:HMMER | 0.9781 | 0.0790 | 0.9528 | 1.0033 | Eukaryote | GT |
| dbCAN_4:DIAMOND | 0.9707 | 0.0883 | 0.9425 | 0.9990 | Eukaryote | GT |
| dbCAN_4:dbCAN-sub | 0.9752 | 0.0785 | 0.9501 | 1.0003 | Eukaryote | GT |
| CUPP | 0.9771 | 0.0874 | 0.9491 | 1.0050 | Eukaryote | GT |
| dbCAN_2 | 0.9532 | 0.2052 | 0.8929 | 1.0134 | All | PL |
| dbCAN_2:HMMER | 0.9745 | 0.1481 | 0.9310 | 1.0180 | All | PL |
| dbCAN_2:DIAMOND | 0.9248 | 0.2505 | 0.8513 | 0.9984 | All | PL |
| dbCAN_2:Hotpep | 0.9506 | 0.2050 | 0.8904 | 1.0108 | All | PL |
| dbCAN_3 | 0.9846 | 0.0766 | 0.9621 | 1.0071 | All | PL |
| dbCAN_3:HMMER | 0.9846 | 0.0766 | 0.9621 | 1.0071 | All | PL |
| dbCAN_3:DIAMOND | 0.9730 | 0.1012 | 0.9433 | 1.0028 | All | PL |
| dbCAN_3:eCAMI | 0.9333 | 0.2452 | 0.8621 | 1.0045 | All | PL |
| dbCAN_4 | 0.9846 | 0.0766 | 0.9621 | 1.0071 | All | PL |
| dbCAN_4:HMMER | 0.9846 | 0.0766 | 0.9621 | 1.0071 | All | PL |
| dbCAN_4:DIAMOND | 0.9730 | 0.1012 | 0.9433 | 1.0028 | All | PL |
| dbCAN_4:dbCAN-sub | 0.9846 | 0.0766 | 0.9621 | 1.0071 | All | PL |
| CUPP | 0.9496 | 0.2058 | 0.8892 | 1.0101 | All | PL |
| dbCAN_2 | 0.9667 | 0.1826 | 0.8985 | 1.0348 | Bacteria | PL |
| dbCAN_2:HMMER | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | PL |
| dbCAN_2:DIAMOND | 0.9556 | 0.1904 | 0.8844 | 1.0267 | Bacteria | PL |
| dbCAN_2:Hotpep | 0.9960 | 0.0154 | 0.9902 | 1.0017 | Bacteria | PL |
| dbCAN_3 | 0.9980 | 0.0107 | 0.9940 | 1.0020 | Bacteria | PL |
| dbCAN_3:HMMER | 0.9980 | 0.0107 | 0.9940 | 1.0020 | Bacteria | PL |
| dbCAN_3:DIAMOND | 0.9869 | 0.0614 | 0.9640 | 1.0099 | Bacteria | PL |
| dbCAN_3:eCAMI | 0.9677 | 0.1796 | 0.9019 | 1.0336 | Bacteria | PL |
| dbCAN_4 | 0.9980 | 0.0107 | 0.9940 | 1.0020 | Bacteria | PL |
| dbCAN_4:HMMER | 0.9980 | 0.0107 | 0.9940 | 1.0020 | Bacteria | PL |
| dbCAN_4:DIAMOND | 0.9869 | 0.0614 | 0.9640 | 1.0099 | Bacteria | PL |
| dbCAN_4:dbCAN-sub | 0.9980 | 0.0107 | 0.9940 | 1.0020 | Bacteria | PL |
| CUPP | 0.9667 | 0.1826 | 0.8985 | 1.0348 | Bacteria | PL |
| dbCAN_2 | 0.9294 | 0.2443 | 0.8038 | 1.0550 | Eukaryote | PL |
| dbCAN_2:HMMER | 0.9294 | 0.2443 | 0.8038 | 1.0550 | Eukaryote | PL |
| dbCAN_2:DIAMOND | 0.8706 | 0.3312 | 0.7003 | 1.0409 | Eukaryote | PL |
| dbCAN_2:Hotpep | 0.8706 | 0.3312 | 0.7003 | 1.0409 | Eukaryote | PL |
| dbCAN_3 | 0.9608 | 0.1254 | 0.8963 | 1.0253 | Eukaryote | PL |
| dbCAN_3:HMMER | 0.9608 | 0.1254 | 0.8963 | 1.0253 | Eukaryote | PL |
| dbCAN_3:DIAMOND | 0.9485 | 0.1470 | 0.8730 | 1.0241 | Eukaryote | PL |
| dbCAN_3:eCAMI | 0.8706 | 0.3312 | 0.7003 | 1.0409 | Eukaryote | PL |
| dbCAN_4 | 0.9608 | 0.1254 | 0.8963 | 1.0253 | Eukaryote | PL |
| dbCAN_4:HMMER | 0.9608 | 0.1254 | 0.8963 | 1.0253 | Eukaryote | PL |
| dbCAN_4:DIAMOND | 0.9485 | 0.1470 | 0.8730 | 1.0241 | Eukaryote | PL |
| dbCAN_4:dbCAN-sub | 0.9608 | 0.1254 | 0.8963 | 1.0253 | Eukaryote | PL |
| CUPP | 0.9196 | 0.2447 | 0.7938 | 1.0454 | Eukaryote | PL |
| dbCAN_2 | 0.9519 | 0.1408 | 0.9197 | 0.9840 | All | CE |
| dbCAN_2:HMMER | 0.9525 | 0.1191 | 0.9253 | 0.9797 | All | CE |
| dbCAN_2:DIAMOND | 0.9280 | 0.2089 | 0.8803 | 0.9757 | All | CE |
| dbCAN_2:Hotpep | 0.9128 | 0.1671 | 0.8746 | 0.9510 | All | CE |
| dbCAN_3 | 0.9526 | 0.1391 | 0.9208 | 0.9844 | All | CE |
| dbCAN_3:HMMER | 0.9602 | 0.1103 | 0.9350 | 0.9854 | All | CE |
| dbCAN_3:DIAMOND | 0.9304 | 0.1864 | 0.8878 | 0.9730 | All | CE |
| dbCAN_3:eCAMI | 0.9156 | 0.1909 | 0.8719 | 0.9592 | All | CE |
| dbCAN_4 | 0.9603 | 0.1103 | 0.9351 | 0.9855 | All | CE |
| dbCAN_4:HMMER | 0.9603 | 0.1103 | 0.9351 | 0.9855 | All | CE |
| dbCAN_4:DIAMOND | 0.9476 | 0.1506 | 0.9132 | 0.9820 | All | CE |
| dbCAN_4:dbCAN-sub | 0.9592 | 0.1120 | 0.9336 | 0.9848 | All | CE |
| CUPP | 0.9598 | 0.1130 | 0.9339 | 0.9856 | All | CE |
| dbCAN_2 | 0.9148 | 0.1833 | 0.8562 | 0.9734 | Bacteria | CE |
| dbCAN_2:HMMER | 0.9218 | 0.1527 | 0.8729 | 0.9706 | Bacteria | CE |
| dbCAN_2:DIAMOND | 0.9182 | 0.1867 | 0.8585 | 0.9779 | Bacteria | CE |
| dbCAN_2:Hotpep | 0.8560 | 0.2018 | 0.7914 | 0.9205 | Bacteria | CE |
| dbCAN_3 | 0.9149 | 0.1821 | 0.8567 | 0.9732 | Bacteria | CE |
| dbCAN_3:HMMER | 0.9322 | 0.1429 | 0.8865 | 0.9779 | Bacteria | CE |
| dbCAN_3:DIAMOND | 0.9219 | 0.1752 | 0.8658 | 0.9779 | Bacteria | CE |
| dbCAN_3:eCAMI | 0.8681 | 0.2000 | 0.8042 | 0.9321 | Bacteria | CE |
| dbCAN_4 | 0.9324 | 0.1429 | 0.8867 | 0.9781 | Bacteria | CE |
| dbCAN_4:HMMER | 0.9324 | 0.1429 | 0.8867 | 0.9781 | Bacteria | CE |
| dbCAN_4:DIAMOND | 0.9295 | 0.1739 | 0.8739 | 0.9851 | Bacteria | CE |
| dbCAN_4:dbCAN-sub | 0.9321 | 0.1429 | 0.8864 | 0.9778 | Bacteria | CE |
| CUPP | 0.9298 | 0.1452 | 0.8834 | 0.9762 | Bacteria | CE |
| dbCAN_2 | 0.9931 | 0.0417 | 0.9790 | 1.0072 | Eukaryote | CE |
| dbCAN_2:HMMER | 0.9867 | 0.0459 | 0.9712 | 1.0023 | Eukaryote | CE |
| dbCAN_2:DIAMOND | 0.9389 | 0.2333 | 0.8599 | 1.0178 | Eukaryote | CE |
| dbCAN_2:Hotpep | 0.9759 | 0.0818 | 0.9482 | 1.0035 | Eukaryote | CE |
| dbCAN_3 | 0.9944 | 0.0333 | 0.9832 | 1.0057 | Eukaryote | CE |
| dbCAN_3:HMMER | 0.9914 | 0.0377 | 0.9786 | 1.0041 | Eukaryote | CE |
| dbCAN_3:DIAMOND | 0.9399 | 0.2002 | 0.8722 | 1.0076 | Eukaryote | CE |
| dbCAN_3:eCAMI | 0.9683 | 0.1677 | 0.9115 | 1.0250 | Eukaryote | CE |
| dbCAN_4 | 0.9914 | 0.0377 | 0.9786 | 1.0041 | Eukaryote | CE |
| dbCAN_4:HMMER | 0.9914 | 0.0377 | 0.9786 | 1.0041 | Eukaryote | CE |
| dbCAN_4:DIAMOND | 0.9677 | 0.1189 | 0.9275 | 1.0079 | Eukaryote | CE |
| dbCAN_4:dbCAN-sub | 0.9893 | 0.0486 | 0.9729 | 1.0058 | Eukaryote | CE |
| CUPP | 0.9931 | 0.0417 | 0.9790 | 1.0072 | Eukaryote | CE |
| dbCAN_2 | 0.9208 | 0.1693 | 0.8716 | 0.9699 | All | AA |
| dbCAN_2:HMMER | 0.9191 | 0.1607 | 0.8724 | 0.9658 | All | AA |
| dbCAN_2:DIAMOND | 0.9228 | 0.1710 | 0.8731 | 0.9724 | All | AA |
| dbCAN_2:Hotpep | 0.8983 | 0.2166 | 0.8354 | 0.9612 | All | AA |
| dbCAN_3 | 0.9236 | 0.1605 | 0.8770 | 0.9702 | All | AA |
| dbCAN_3:HMMER | 0.9192 | 0.1624 | 0.8720 | 0.9664 | All | AA |
| dbCAN_3:DIAMOND | 0.9171 | 0.1693 | 0.8679 | 0.9662 | All | AA |
| dbCAN_3:eCAMI | 0.8514 | 0.2809 | 0.7699 | 0.9330 | All | AA |
| dbCAN_4 | 0.9198 | 0.1610 | 0.8731 | 0.9666 | All | AA |
| dbCAN_4:HMMER | 0.9192 | 0.1624 | 0.8720 | 0.9664 | All | AA |
| dbCAN_4:DIAMOND | 0.9196 | 0.1697 | 0.8703 | 0.9689 | All | AA |
| dbCAN_4:dbCAN-sub | 0.9177 | 0.1620 | 0.8707 | 0.9648 | All | AA |
| CUPP | 0.9184 | 0.1697 | 0.8691 | 0.9677 | All | AA |
| dbCAN_2 | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_2:HMMER | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_2:DIAMOND | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_2:Hotpep | 0.9091 | 0.3015 | 0.7065 | 1.1116 | Bacteria | AA |
| dbCAN_3 | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_3:HMMER | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_3:DIAMOND | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_3:eCAMI | 0.9091 | 0.3015 | 0.7065 | 1.1116 | Bacteria | AA |
| dbCAN_4 | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_4:HMMER | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_4:DIAMOND | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_4:dbCAN-sub | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| CUPP | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_2 | 0.8972 | 0.1869 | 0.8349 | 0.9595 | Eukaryote | AA |
| dbCAN_2:HMMER | 0.8950 | 0.1764 | 0.8362 | 0.9539 | Eukaryote | AA |
| dbCAN_2:DIAMOND | 0.8998 | 0.1892 | 0.8367 | 0.9629 | Eukaryote | AA |
| dbCAN_2:Hotpep | 0.8951 | 0.1896 | 0.8319 | 0.9583 | Eukaryote | AA |
| dbCAN_3 | 0.9009 | 0.1770 | 0.8419 | 0.9599 | Eukaryote | AA |
| dbCAN_3:HMMER | 0.8952 | 0.1785 | 0.8357 | 0.9547 | Eukaryote | AA |
| dbCAN_3:DIAMOND | 0.8925 | 0.1862 | 0.8304 | 0.9545 | Eukaryote | AA |
| dbCAN_3:eCAMI | 0.8343 | 0.2765 | 0.7421 | 0.9264 | Eukaryote | AA |
| dbCAN_4 | 0.8960 | 0.1769 | 0.8370 | 0.9550 | Eukaryote | AA |
| dbCAN_4:HMMER | 0.8952 | 0.1785 | 0.8357 | 0.9547 | Eukaryote | AA |
| dbCAN_4:DIAMOND | 0.8957 | 0.1872 | 0.8333 | 0.9581 | Eukaryote | AA |
| dbCAN_4:dbCAN-sub | 0.8932 | 0.1777 | 0.8340 | 0.9525 | Eukaryote | AA |
| CUPP | 0.8942 | 0.1870 | 0.8318 | 0.9565 | Eukaryote | AA |
| dbCAN_2 | 0.9203 | 0.1333 | 0.8906 | 0.9500 | All | CBM |
| dbCAN_2:HMMER | 0.8965 | 0.2304 | 0.8452 | 0.9478 | All | CBM |
| dbCAN_2:DIAMOND | 0.9219 | 0.1502 | 0.8885 | 0.9553 | All | CBM |
| dbCAN_2:Hotpep | 0.4696 | 0.1731 | 0.4311 | 0.5081 | All | CBM |
| dbCAN_3 | 0.9431 | 0.1355 | 0.9129 | 0.9732 | All | CBM |
| dbCAN_3:HMMER | 0.8964 | 0.2304 | 0.8451 | 0.9476 | All | CBM |
| dbCAN_3:DIAMOND | 0.9512 | 0.1283 | 0.9227 | 0.9797 | All | CBM |
| dbCAN_3:eCAMI | 0.6615 | 0.2254 | 0.6113 | 0.7117 | All | CBM |
| dbCAN_4 | 0.9562 | 0.0919 | 0.9358 | 0.9767 | All | CBM |
| dbCAN_4:HMMER | 0.9184 | 0.1999 | 0.8739 | 0.9629 | All | CBM |
| dbCAN_4:DIAMOND | 0.9571 | 0.1273 | 0.9288 | 0.9854 | All | CBM |
| dbCAN_4:dbCAN-sub | 0.9376 | 0.1151 | 0.9120 | 0.9632 | All | CBM |
| CUPP | 0.0000 | 0.0000 | 0.0000 | 0.0000 | All | CBM |
| dbCAN_2 | 0.9517 | 0.1091 | 0.9168 | 0.9866 | Bacteria | CBM |
| dbCAN_2:HMMER | 0.9380 | 0.1365 | 0.8944 | 0.9817 | Bacteria | CBM |
| dbCAN_2:DIAMOND | 0.9551 | 0.1626 | 0.9031 | 1.0071 | Bacteria | CBM |
| dbCAN_2:Hotpep | 0.4795 | 0.2000 | 0.4156 | 0.5435 | Bacteria | CBM |
| dbCAN_3 | 0.9384 | 0.1704 | 0.8839 | 0.9929 | Bacteria | CBM |
| dbCAN_3:HMMER | 0.9377 | 0.1365 | 0.8941 | 0.9814 | Bacteria | CBM |
| dbCAN_3:DIAMOND | 0.9600 | 0.1592 | 0.9091 | 1.0109 | Bacteria | CBM |
| dbCAN_3:eCAMI | 0.6317 | 0.2308 | 0.5579 | 0.7055 | Bacteria | CBM |
| dbCAN_4 | 0.9699 | 0.0662 | 0.9487 | 0.9911 | Bacteria | CBM |
| dbCAN_4:HMMER | 0.9524 | 0.1130 | 0.9163 | 0.9886 | Bacteria | CBM |
| dbCAN_4:DIAMOND | 0.9604 | 0.1591 | 0.9095 | 1.0113 | Bacteria | CBM |
| dbCAN_4:dbCAN-sub | 0.9624 | 0.0681 | 0.9406 | 0.9842 | Bacteria | CBM |
| CUPP | 0.0000 | 0.0000 | 0.0000 | 0.0000 | Bacteria | CBM |
| dbCAN_2 | 0.8889 | 0.1486 | 0.8414 | 0.9364 | Eukaryote | CBM |
| dbCAN_2:HMMER | 0.8550 | 0.2922 | 0.7616 | 0.9484 | Eukaryote | CBM |
| dbCAN_2:DIAMOND | 0.8887 | 0.1303 | 0.8471 | 0.9304 | Eukaryote | CBM |
| dbCAN_2:Hotpep | 0.4597 | 0.1431 | 0.4139 | 0.5055 | Eukaryote | CBM |
| dbCAN_3 | 0.9477 | 0.0901 | 0.9189 | 0.9765 | Eukaryote | CBM |
| dbCAN_3:HMMER | 0.8550 | 0.2922 | 0.7616 | 0.9484 | Eukaryote | CBM |
| dbCAN_3:DIAMOND | 0.9424 | 0.0885 | 0.9141 | 0.9707 | Eukaryote | CBM |
| dbCAN_3:eCAMI | 0.6913 | 0.2188 | 0.6214 | 0.7613 | Eukaryote | CBM |
| dbCAN_4 | 0.9426 | 0.1111 | 0.9071 | 0.9781 | Eukaryote | CBM |
| dbCAN_4:HMMER | 0.8844 | 0.2565 | 0.8023 | 0.9664 | Eukaryote | CBM |
| dbCAN_4:DIAMOND | 0.9538 | 0.0865 | 0.9261 | 0.9815 | Eukaryote | CBM |
| dbCAN_4:dbCAN-sub | 0.9128 | 0.1447 | 0.8665 | 0.9591 | Eukaryote | CBM |
| CUPP | 0.0000 | 0.0000 | 0.0000 | 0.0000 | Eukaryote | CBM |
## png
## 2
## png
## 2
| Prediction_tool | Mean | Standard Deviation | LowerCI | UpperCI | Tax_group | CAZy_class |
|---|---|---|---|---|---|---|
| dbCAN_2 | 0.9583 | 0.0614 | 0.9446 | 0.9719 | All | GH |
| dbCAN_2:HMMER | 0.9444 | 0.0587 | 0.9313 | 0.9574 | All | GH |
| dbCAN_2:DIAMOND | 0.9563 | 0.0727 | 0.9401 | 0.9725 | All | GH |
| dbCAN_2:Hotpep | 0.9136 | 0.0773 | 0.8964 | 0.9308 | All | GH |
| dbCAN_3 | 0.9708 | 0.0558 | 0.9583 | 0.9832 | All | GH |
| dbCAN_3:HMMER | 0.9514 | 0.0596 | 0.9382 | 0.9647 | All | GH |
| dbCAN_3:DIAMOND | 0.9776 | 0.0491 | 0.9666 | 0.9885 | All | GH |
| dbCAN_3:eCAMI | 0.9223 | 0.0695 | 0.9069 | 0.9378 | All | GH |
| dbCAN_4 | 0.9671 | 0.0590 | 0.9539 | 0.9802 | All | GH |
| dbCAN_4:HMMER | 0.9516 | 0.0596 | 0.9384 | 0.9649 | All | GH |
| dbCAN_4:DIAMOND | 0.9764 | 0.0583 | 0.9634 | 0.9894 | All | GH |
| dbCAN_4:dbCAN-sub | 0.9655 | 0.0581 | 0.9526 | 0.9785 | All | GH |
| CUPP | 0.9461 | 0.0454 | 0.9360 | 0.9562 | All | GH |
| dbCAN_2 | 0.9592 | 0.0692 | 0.9371 | 0.9814 | Bacteria | GH |
| dbCAN_2:HMMER | 0.9464 | 0.0769 | 0.9218 | 0.9710 | Bacteria | GH |
| dbCAN_2:DIAMOND | 0.9535 | 0.0809 | 0.9277 | 0.9794 | Bacteria | GH |
| dbCAN_2:Hotpep | 0.9308 | 0.0630 | 0.9106 | 0.9509 | Bacteria | GH |
| dbCAN_3 | 0.9718 | 0.0713 | 0.9490 | 0.9947 | Bacteria | GH |
| dbCAN_3:HMMER | 0.9495 | 0.0782 | 0.9245 | 0.9745 | Bacteria | GH |
| dbCAN_3:DIAMOND | 0.9723 | 0.0614 | 0.9527 | 0.9919 | Bacteria | GH |
| dbCAN_3:eCAMI | 0.9423 | 0.0641 | 0.9218 | 0.9628 | Bacteria | GH |
| dbCAN_4 | 0.9682 | 0.0776 | 0.9434 | 0.9930 | Bacteria | GH |
| dbCAN_4:HMMER | 0.9499 | 0.0782 | 0.9249 | 0.9749 | Bacteria | GH |
| dbCAN_4:DIAMOND | 0.9694 | 0.0764 | 0.9449 | 0.9938 | Bacteria | GH |
| dbCAN_4:dbCAN-sub | 0.9690 | 0.0761 | 0.9447 | 0.9933 | Bacteria | GH |
| CUPP | 0.9516 | 0.0487 | 0.9360 | 0.9672 | Bacteria | GH |
| dbCAN_2 | 0.9573 | 0.0533 | 0.9403 | 0.9744 | Eukaryote | GH |
| dbCAN_2:HMMER | 0.9423 | 0.0327 | 0.9319 | 0.9528 | Eukaryote | GH |
| dbCAN_2:DIAMOND | 0.9590 | 0.0644 | 0.9384 | 0.9796 | Eukaryote | GH |
| dbCAN_2:Hotpep | 0.8965 | 0.0868 | 0.8687 | 0.9242 | Eukaryote | GH |
| dbCAN_3 | 0.9697 | 0.0350 | 0.9585 | 0.9809 | Eukaryote | GH |
| dbCAN_3:HMMER | 0.9534 | 0.0329 | 0.9429 | 0.9639 | Eukaryote | GH |
| dbCAN_3:DIAMOND | 0.9828 | 0.0327 | 0.9724 | 0.9933 | Eukaryote | GH |
| dbCAN_3:eCAMI | 0.9023 | 0.0698 | 0.8800 | 0.9247 | Eukaryote | GH |
| dbCAN_4 | 0.9659 | 0.0319 | 0.9557 | 0.9761 | Eukaryote | GH |
| dbCAN_4:HMMER | 0.9534 | 0.0329 | 0.9429 | 0.9639 | Eukaryote | GH |
| dbCAN_4:DIAMOND | 0.9834 | 0.0307 | 0.9736 | 0.9932 | Eukaryote | GH |
| dbCAN_4:dbCAN-sub | 0.9621 | 0.0320 | 0.9519 | 0.9723 | Eukaryote | GH |
| CUPP | 0.9405 | 0.0416 | 0.9272 | 0.9538 | Eukaryote | GH |
| dbCAN_2 | 0.9258 | 0.1016 | 0.9032 | 0.9484 | All | GT |
| dbCAN_2:HMMER | 0.9152 | 0.0845 | 0.8964 | 0.9340 | All | GT |
| dbCAN_2:DIAMOND | 0.9463 | 0.1124 | 0.9213 | 0.9713 | All | GT |
| dbCAN_2:Hotpep | 0.8209 | 0.1383 | 0.7901 | 0.8517 | All | GT |
| dbCAN_3 | 0.9606 | 0.0790 | 0.9430 | 0.9782 | All | GT |
| dbCAN_3:HMMER | 0.9169 | 0.0839 | 0.8982 | 0.9355 | All | GT |
| dbCAN_3:DIAMOND | 0.9764 | 0.0755 | 0.9596 | 0.9932 | All | GT |
| dbCAN_3:eCAMI | 0.9046 | 0.1076 | 0.8806 | 0.9285 | All | GT |
| dbCAN_4 | 0.9677 | 0.0753 | 0.9510 | 0.9845 | All | GT |
| dbCAN_4:HMMER | 0.9170 | 0.0838 | 0.8984 | 0.9357 | All | GT |
| dbCAN_4:DIAMOND | 0.9750 | 0.0781 | 0.9577 | 0.9924 | All | GT |
| dbCAN_4:dbCAN-sub | 0.9664 | 0.0656 | 0.9518 | 0.9810 | All | GT |
| CUPP | 0.9107 | 0.0758 | 0.8938 | 0.9276 | All | GT |
| dbCAN_2 | 0.9294 | 0.1020 | 0.8968 | 0.9620 | Bacteria | GT |
| dbCAN_2:HMMER | 0.9110 | 0.1012 | 0.8786 | 0.9434 | Bacteria | GT |
| dbCAN_2:DIAMOND | 0.9506 | 0.1147 | 0.9139 | 0.9873 | Bacteria | GT |
| dbCAN_2:Hotpep | 0.7903 | 0.1418 | 0.7449 | 0.8357 | Bacteria | GT |
| dbCAN_3 | 0.9584 | 0.0970 | 0.9274 | 0.9894 | Bacteria | GT |
| dbCAN_3:HMMER | 0.9106 | 0.1007 | 0.8784 | 0.9428 | Bacteria | GT |
| dbCAN_3:DIAMOND | 0.9758 | 0.0925 | 0.9462 | 1.0054 | Bacteria | GT |
| dbCAN_3:eCAMI | 0.9112 | 0.1075 | 0.8768 | 0.9455 | Bacteria | GT |
| dbCAN_4 | 0.9647 | 0.0958 | 0.9340 | 0.9953 | Bacteria | GT |
| dbCAN_4:HMMER | 0.9112 | 0.1007 | 0.8790 | 0.9434 | Bacteria | GT |
| dbCAN_4:DIAMOND | 0.9695 | 0.0962 | 0.9387 | 1.0003 | Bacteria | GT |
| dbCAN_4:dbCAN-sub | 0.9660 | 0.0801 | 0.9404 | 0.9917 | Bacteria | GT |
| CUPP | 0.9292 | 0.0713 | 0.9064 | 0.9520 | Bacteria | GT |
| dbCAN_2 | 0.9222 | 0.1023 | 0.8895 | 0.9550 | Eukaryote | GT |
| dbCAN_2:HMMER | 0.9194 | 0.0648 | 0.8987 | 0.9401 | Eukaryote | GT |
| dbCAN_2:DIAMOND | 0.9420 | 0.1112 | 0.9064 | 0.9776 | Eukaryote | GT |
| dbCAN_2:Hotpep | 0.8515 | 0.1293 | 0.8101 | 0.8928 | Eukaryote | GT |
| dbCAN_3 | 0.9628 | 0.0569 | 0.9446 | 0.9810 | Eukaryote | GT |
| dbCAN_3:HMMER | 0.9231 | 0.0636 | 0.9028 | 0.9435 | Eukaryote | GT |
| dbCAN_3:DIAMOND | 0.9769 | 0.0547 | 0.9595 | 0.9944 | Eukaryote | GT |
| dbCAN_3:eCAMI | 0.8980 | 0.1085 | 0.8633 | 0.9327 | Eukaryote | GT |
| dbCAN_4 | 0.9708 | 0.0479 | 0.9555 | 0.9861 | Eukaryote | GT |
| dbCAN_4:HMMER | 0.9229 | 0.0634 | 0.9026 | 0.9432 | Eukaryote | GT |
| dbCAN_4:DIAMOND | 0.9806 | 0.0551 | 0.9630 | 0.9982 | Eukaryote | GT |
| dbCAN_4:dbCAN-sub | 0.9667 | 0.0481 | 0.9513 | 0.9821 | Eukaryote | GT |
| CUPP | 0.8923 | 0.0766 | 0.8678 | 0.9168 | Eukaryote | GT |
| dbCAN_2 | 0.9073 | 0.2183 | 0.8432 | 0.9714 | All | PL |
| dbCAN_2:HMMER | 0.9250 | 0.1788 | 0.8725 | 0.9775 | All | PL |
| dbCAN_2:DIAMOND | 0.8889 | 0.2530 | 0.8146 | 0.9632 | All | PL |
| dbCAN_2:Hotpep | 0.8803 | 0.2257 | 0.8140 | 0.9465 | All | PL |
| dbCAN_3 | 0.9826 | 0.0689 | 0.9624 | 1.0028 | All | PL |
| dbCAN_3:HMMER | 0.9741 | 0.0781 | 0.9511 | 0.9970 | All | PL |
| dbCAN_3:DIAMOND | 0.9754 | 0.0792 | 0.9521 | 0.9986 | All | PL |
| dbCAN_3:eCAMI | 0.8473 | 0.2533 | 0.7737 | 0.9208 | All | PL |
| dbCAN_4 | 0.9741 | 0.0781 | 0.9511 | 0.9970 | All | PL |
| dbCAN_4:HMMER | 0.9741 | 0.0781 | 0.9511 | 0.9970 | All | PL |
| dbCAN_4:DIAMOND | 0.9825 | 0.0646 | 0.9635 | 1.0014 | All | PL |
| dbCAN_4:dbCAN-sub | 0.9747 | 0.0782 | 0.9518 | 0.9977 | All | PL |
| CUPP | 0.8850 | 0.2288 | 0.8178 | 0.9522 | All | PL |
| dbCAN_2 | 0.9329 | 0.1918 | 0.8612 | 1.0045 | Bacteria | PL |
| dbCAN_2:HMMER | 0.9495 | 0.1139 | 0.9070 | 0.9921 | Bacteria | PL |
| dbCAN_2:DIAMOND | 0.9373 | 0.1869 | 0.8675 | 1.0071 | Bacteria | PL |
| dbCAN_2:Hotpep | 0.9175 | 0.1327 | 0.8679 | 0.9670 | Bacteria | PL |
| dbCAN_3 | 0.9869 | 0.0610 | 0.9641 | 1.0096 | Bacteria | PL |
| dbCAN_3:HMMER | 0.9735 | 0.0770 | 0.9448 | 1.0023 | Bacteria | PL |
| dbCAN_3:DIAMOND | 0.9913 | 0.0369 | 0.9775 | 1.0051 | Bacteria | PL |
| dbCAN_3:eCAMI | 0.8734 | 0.2083 | 0.7970 | 0.9498 | Bacteria | PL |
| dbCAN_4 | 0.9735 | 0.0770 | 0.9448 | 1.0023 | Bacteria | PL |
| dbCAN_4:HMMER | 0.9735 | 0.0770 | 0.9448 | 1.0023 | Bacteria | PL |
| dbCAN_4:DIAMOND | 0.9913 | 0.0369 | 0.9775 | 1.0051 | Bacteria | PL |
| dbCAN_4:dbCAN-sub | 0.9745 | 0.0771 | 0.9457 | 1.0034 | Bacteria | PL |
| CUPP | 0.8899 | 0.2178 | 0.8085 | 0.9712 | Bacteria | PL |
| dbCAN_2 | 0.8622 | 0.2587 | 0.7292 | 0.9952 | Eukaryote | PL |
| dbCAN_2:HMMER | 0.8818 | 0.2556 | 0.7504 | 1.0132 | Eukaryote | PL |
| dbCAN_2:DIAMOND | 0.8034 | 0.3294 | 0.6340 | 0.9727 | Eukaryote | PL |
| dbCAN_2:Hotpep | 0.8146 | 0.3277 | 0.6461 | 0.9831 | Eukaryote | PL |
| dbCAN_3 | 0.9750 | 0.0825 | 0.9326 | 1.0174 | Eukaryote | PL |
| dbCAN_3:HMMER | 0.9750 | 0.0825 | 0.9326 | 1.0174 | Eukaryote | PL |
| dbCAN_3:DIAMOND | 0.9472 | 0.1194 | 0.8858 | 1.0086 | Eukaryote | PL |
| dbCAN_3:eCAMI | 0.7996 | 0.3214 | 0.6344 | 0.9649 | Eukaryote | PL |
| dbCAN_4 | 0.9750 | 0.0825 | 0.9326 | 1.0174 | Eukaryote | PL |
| dbCAN_4:HMMER | 0.9750 | 0.0825 | 0.9326 | 1.0174 | Eukaryote | PL |
| dbCAN_4:DIAMOND | 0.9668 | 0.0954 | 0.9178 | 1.0159 | Eukaryote | PL |
| dbCAN_4:dbCAN-sub | 0.9750 | 0.0825 | 0.9326 | 1.0174 | Eukaryote | PL |
| CUPP | 0.8764 | 0.2539 | 0.7459 | 1.0070 | Eukaryote | PL |
| dbCAN_2 | 0.9224 | 0.1305 | 0.8926 | 0.9522 | All | CE |
| dbCAN_2:HMMER | 0.9248 | 0.1119 | 0.8993 | 0.9504 | All | CE |
| dbCAN_2:DIAMOND | 0.8636 | 0.2234 | 0.8126 | 0.9147 | All | CE |
| dbCAN_2:Hotpep | 0.8555 | 0.1705 | 0.8165 | 0.8944 | All | CE |
| dbCAN_3 | 0.9236 | 0.1397 | 0.8916 | 0.9555 | All | CE |
| dbCAN_3:HMMER | 0.9302 | 0.1073 | 0.9057 | 0.9547 | All | CE |
| dbCAN_3:DIAMOND | 0.9152 | 0.1682 | 0.8768 | 0.9537 | All | CE |
| dbCAN_3:eCAMI | 0.8314 | 0.2020 | 0.7852 | 0.8775 | All | CE |
| dbCAN_4 | 0.9638 | 0.0854 | 0.9443 | 0.9833 | All | CE |
| dbCAN_4:HMMER | 0.9487 | 0.0957 | 0.9268 | 0.9706 | All | CE |
| dbCAN_4:DIAMOND | 0.9507 | 0.1192 | 0.9234 | 0.9779 | All | CE |
| dbCAN_4:dbCAN-sub | 0.9617 | 0.0863 | 0.9420 | 0.9814 | All | CE |
| CUPP | 0.9250 | 0.1095 | 0.9000 | 0.9500 | All | CE |
| dbCAN_2 | 0.9052 | 0.1414 | 0.8600 | 0.9505 | Bacteria | CE |
| dbCAN_2:HMMER | 0.8823 | 0.1265 | 0.8419 | 0.9228 | Bacteria | CE |
| dbCAN_2:DIAMOND | 0.8759 | 0.1626 | 0.8239 | 0.9279 | Bacteria | CE |
| dbCAN_2:Hotpep | 0.8730 | 0.1582 | 0.8224 | 0.9236 | Bacteria | CE |
| dbCAN_3 | 0.8941 | 0.1625 | 0.8421 | 0.9460 | Bacteria | CE |
| dbCAN_3:HMMER | 0.8875 | 0.1215 | 0.8486 | 0.9264 | Bacteria | CE |
| dbCAN_3:DIAMOND | 0.9092 | 0.1444 | 0.8630 | 0.9554 | Bacteria | CE |
| dbCAN_3:eCAMI | 0.8444 | 0.1781 | 0.7874 | 0.9013 | Bacteria | CE |
| dbCAN_4 | 0.9400 | 0.1099 | 0.9049 | 0.9751 | Bacteria | CE |
| dbCAN_4:HMMER | 0.9143 | 0.1191 | 0.8762 | 0.9524 | Bacteria | CE |
| dbCAN_4:DIAMOND | 0.9299 | 0.1425 | 0.8843 | 0.9754 | Bacteria | CE |
| dbCAN_4:dbCAN-sub | 0.9381 | 0.1101 | 0.9029 | 0.9733 | Bacteria | CE |
| CUPP | 0.9000 | 0.1196 | 0.8617 | 0.9382 | Bacteria | CE |
| dbCAN_2 | 0.9415 | 0.1162 | 0.9022 | 0.9808 | Eukaryote | CE |
| dbCAN_2:HMMER | 0.9721 | 0.0682 | 0.9490 | 0.9952 | Eukaryote | CE |
| dbCAN_2:DIAMOND | 0.8501 | 0.2777 | 0.7561 | 0.9440 | Eukaryote | CE |
| dbCAN_2:Hotpep | 0.8360 | 0.1836 | 0.7739 | 0.8981 | Eukaryote | CE |
| dbCAN_3 | 0.9563 | 0.1017 | 0.9219 | 0.9908 | Eukaryote | CE |
| dbCAN_3:HMMER | 0.9777 | 0.0616 | 0.9568 | 0.9985 | Eukaryote | CE |
| dbCAN_3:DIAMOND | 0.9219 | 0.1931 | 0.8566 | 0.9873 | Eukaryote | CE |
| dbCAN_3:eCAMI | 0.8169 | 0.2274 | 0.7400 | 0.8939 | Eukaryote | CE |
| dbCAN_4 | 0.9902 | 0.0287 | 0.9805 | 1.0000 | Eukaryote | CE |
| dbCAN_4:HMMER | 0.9869 | 0.0309 | 0.9765 | 0.9974 | Eukaryote | CE |
| dbCAN_4:DIAMOND | 0.9738 | 0.0823 | 0.9459 | 1.0016 | Eukaryote | CE |
| dbCAN_4:dbCAN-sub | 0.9880 | 0.0335 | 0.9766 | 0.9993 | Eukaryote | CE |
| CUPP | 0.9528 | 0.0907 | 0.9221 | 0.9835 | Eukaryote | CE |
| dbCAN_2 | 0.9104 | 0.1322 | 0.8720 | 0.9488 | All | AA |
| dbCAN_2:HMMER | 0.9173 | 0.1137 | 0.8843 | 0.9503 | All | AA |
| dbCAN_2:DIAMOND | 0.8766 | 0.1603 | 0.8301 | 0.9232 | All | AA |
| dbCAN_2:Hotpep | 0.8733 | 0.1924 | 0.8174 | 0.9292 | All | AA |
| dbCAN_3 | 0.9436 | 0.1100 | 0.9117 | 0.9756 | All | AA |
| dbCAN_3:HMMER | 0.9434 | 0.1112 | 0.9111 | 0.9757 | All | AA |
| dbCAN_3:DIAMOND | 0.9413 | 0.1144 | 0.9080 | 0.9745 | All | AA |
| dbCAN_3:eCAMI | 0.8006 | 0.2558 | 0.7263 | 0.8749 | All | AA |
| dbCAN_4 | 0.9464 | 0.1085 | 0.9149 | 0.9779 | All | AA |
| dbCAN_4:HMMER | 0.9434 | 0.1112 | 0.9111 | 0.9757 | All | AA |
| dbCAN_4:DIAMOND | 0.9306 | 0.1226 | 0.8950 | 0.9662 | All | AA |
| dbCAN_4:dbCAN-sub | 0.9430 | 0.1090 | 0.9113 | 0.9746 | All | AA |
| CUPP | 0.9011 | 0.1376 | 0.8611 | 0.9410 | All | AA |
| dbCAN_2 | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_2:HMMER | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_2:DIAMOND | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_2:Hotpep | 0.9091 | 0.3015 | 0.7065 | 1.1116 | Bacteria | AA |
| dbCAN_3 | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_3:HMMER | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_3:DIAMOND | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_3:eCAMI | 0.9091 | 0.3015 | 0.7065 | 1.1116 | Bacteria | AA |
| dbCAN_4 | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_4:HMMER | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_4:DIAMOND | 0.9697 | 0.1005 | 0.9022 | 1.0372 | Bacteria | AA |
| dbCAN_4:dbCAN-sub | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| CUPP | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_2 | 0.8838 | 0.1401 | 0.8371 | 0.9305 | Eukaryote | AA |
| dbCAN_2:HMMER | 0.8927 | 0.1190 | 0.8530 | 0.9324 | Eukaryote | AA |
| dbCAN_2:DIAMOND | 0.8399 | 0.1659 | 0.7846 | 0.8952 | Eukaryote | AA |
| dbCAN_2:Hotpep | 0.8626 | 0.1503 | 0.8125 | 0.9127 | Eukaryote | AA |
| dbCAN_3 | 0.9269 | 0.1205 | 0.8867 | 0.9670 | Eukaryote | AA |
| dbCAN_3:HMMER | 0.9266 | 0.1219 | 0.8860 | 0.9673 | Eukaryote | AA |
| dbCAN_3:DIAMOND | 0.9238 | 0.1254 | 0.8820 | 0.9656 | Eukaryote | AA |
| dbCAN_3:eCAMI | 0.7683 | 0.2356 | 0.6898 | 0.8469 | Eukaryote | AA |
| dbCAN_4 | 0.9305 | 0.1193 | 0.8907 | 0.9703 | Eukaryote | AA |
| dbCAN_4:HMMER | 0.9266 | 0.1219 | 0.8860 | 0.9673 | Eukaryote | AA |
| dbCAN_4:DIAMOND | 0.9190 | 0.1274 | 0.8765 | 0.9615 | Eukaryote | AA |
| dbCAN_4:dbCAN-sub | 0.9260 | 0.1193 | 0.8863 | 0.9658 | Eukaryote | AA |
| CUPP | 0.8716 | 0.1443 | 0.8235 | 0.9197 | Eukaryote | AA |
| dbCAN_2 | 0.7970 | 0.1542 | 0.7627 | 0.8314 | All | CBM |
| dbCAN_2:HMMER | 0.5414 | 0.2150 | 0.4935 | 0.5892 | All | CBM |
| dbCAN_2:DIAMOND | 0.8325 | 0.1762 | 0.7933 | 0.8717 | All | CBM |
| dbCAN_2:Hotpep | 0.5508 | 0.1723 | 0.5125 | 0.5892 | All | CBM |
| dbCAN_3 | 0.8354 | 0.1546 | 0.8010 | 0.8698 | All | CBM |
| dbCAN_3:HMMER | 0.5425 | 0.2134 | 0.4950 | 0.5900 | All | CBM |
| dbCAN_3:DIAMOND | 0.8986 | 0.1383 | 0.8678 | 0.9294 | All | CBM |
| dbCAN_3:eCAMI | 0.6810 | 0.2079 | 0.6347 | 0.7272 | All | CBM |
| dbCAN_4 | 0.8547 | 0.1392 | 0.8237 | 0.8857 | All | CBM |
| dbCAN_4:HMMER | 0.5954 | 0.2202 | 0.5464 | 0.6444 | All | CBM |
| dbCAN_4:DIAMOND | 0.9072 | 0.1362 | 0.8768 | 0.9375 | All | CBM |
| dbCAN_4:dbCAN-sub | 0.8576 | 0.1492 | 0.8244 | 0.8908 | All | CBM |
| CUPP | 0.0000 | 0.0000 | 0.0000 | 0.0000 | All | CBM |
| dbCAN_2 | 0.8144 | 0.1600 | 0.7632 | 0.8656 | Bacteria | CBM |
| dbCAN_2:HMMER | 0.6348 | 0.1986 | 0.5712 | 0.6983 | Bacteria | CBM |
| dbCAN_2:DIAMOND | 0.8327 | 0.1875 | 0.7727 | 0.8926 | Bacteria | CBM |
| dbCAN_2:Hotpep | 0.5583 | 0.2060 | 0.4925 | 0.6242 | Bacteria | CBM |
| dbCAN_3 | 0.8330 | 0.1861 | 0.7734 | 0.8925 | Bacteria | CBM |
| dbCAN_3:HMMER | 0.6337 | 0.1981 | 0.5704 | 0.6971 | Bacteria | CBM |
| dbCAN_3:DIAMOND | 0.8648 | 0.1691 | 0.8108 | 0.9189 | Bacteria | CBM |
| dbCAN_3:eCAMI | 0.6709 | 0.2250 | 0.5989 | 0.7428 | Bacteria | CBM |
| dbCAN_4 | 0.9296 | 0.0604 | 0.9103 | 0.9489 | Bacteria | CBM |
| dbCAN_4:HMMER | 0.7163 | 0.1850 | 0.6571 | 0.7755 | Bacteria | CBM |
| dbCAN_4:DIAMOND | 0.8607 | 0.1698 | 0.8063 | 0.9150 | Bacteria | CBM |
| dbCAN_4:dbCAN-sub | 0.9484 | 0.0628 | 0.9283 | 0.9685 | Bacteria | CBM |
| CUPP | 0.0000 | 0.0000 | 0.0000 | 0.0000 | Bacteria | CBM |
| dbCAN_2 | 0.7797 | 0.1483 | 0.7322 | 0.8271 | Eukaryote | CBM |
| dbCAN_2:HMMER | 0.4480 | 0.1904 | 0.3871 | 0.5089 | Eukaryote | CBM |
| dbCAN_2:DIAMOND | 0.8324 | 0.1666 | 0.7791 | 0.8857 | Eukaryote | CBM |
| dbCAN_2:Hotpep | 0.5433 | 0.1325 | 0.5009 | 0.5856 | Eukaryote | CBM |
| dbCAN_3 | 0.8378 | 0.1173 | 0.8003 | 0.8754 | Eukaryote | CBM |
| dbCAN_3:HMMER | 0.4512 | 0.1895 | 0.3906 | 0.5118 | Eukaryote | CBM |
| dbCAN_3:DIAMOND | 0.9323 | 0.0884 | 0.9040 | 0.9606 | Eukaryote | CBM |
| dbCAN_3:eCAMI | 0.6911 | 0.1917 | 0.6297 | 0.7524 | Eukaryote | CBM |
| dbCAN_4 | 0.7798 | 0.1552 | 0.7302 | 0.8295 | Eukaryote | CBM |
| dbCAN_4:HMMER | 0.4745 | 0.1843 | 0.4155 | 0.5334 | Eukaryote | CBM |
| dbCAN_4:DIAMOND | 0.9537 | 0.0657 | 0.9327 | 0.9747 | Eukaryote | CBM |
| dbCAN_4:dbCAN-sub | 0.7669 | 0.1557 | 0.7171 | 0.8166 | Eukaryote | CBM |
| CUPP | 0.0000 | 0.0000 | 0.0000 | 0.0000 | Eukaryote | CBM |
## png
## 2
## png
## 2
| Prediction_tool | Mean | Standard Deviation | LowerCI | UpperCI | Tax_group | CAZy_class |
|---|---|---|---|---|---|---|
| dbCAN_2 | 0.9658 | 0.0361 | 0.9578 | 0.9738 | All | GH |
| dbCAN_2:HMMER | 0.9536 | 0.0330 | 0.9463 | 0.9609 | All | GH |
| dbCAN_2:DIAMOND | 0.9644 | 0.0415 | 0.9551 | 0.9736 | All | GH |
| dbCAN_2:Hotpep | 0.9297 | 0.0495 | 0.9187 | 0.9407 | All | GH |
| dbCAN_3 | 0.9768 | 0.0304 | 0.9701 | 0.9836 | All | GH |
| dbCAN_3:HMMER | 0.9599 | 0.0331 | 0.9525 | 0.9672 | All | GH |
| dbCAN_3:DIAMOND | 0.9812 | 0.0295 | 0.9747 | 0.9878 | All | GH |
| dbCAN_3:eCAMI | 0.9364 | 0.0485 | 0.9256 | 0.9472 | All | GH |
| dbCAN_4 | 0.9743 | 0.0307 | 0.9675 | 0.9812 | All | GH |
| dbCAN_4:HMMER | 0.9601 | 0.0328 | 0.9528 | 0.9674 | All | GH |
| dbCAN_4:DIAMOND | 0.9812 | 0.0304 | 0.9745 | 0.9880 | All | GH |
| dbCAN_4:dbCAN-sub | 0.9731 | 0.0297 | 0.9665 | 0.9797 | All | GH |
| CUPP | 0.9540 | 0.0293 | 0.9475 | 0.9605 | All | GH |
| dbCAN_2 | 0.9660 | 0.0387 | 0.9536 | 0.9784 | Bacteria | GH |
| dbCAN_2:HMMER | 0.9544 | 0.0399 | 0.9416 | 0.9672 | Bacteria | GH |
| dbCAN_2:DIAMOND | 0.9611 | 0.0445 | 0.9469 | 0.9753 | Bacteria | GH |
| dbCAN_2:Hotpep | 0.9375 | 0.0449 | 0.9231 | 0.9518 | Bacteria | GH |
| dbCAN_3 | 0.9788 | 0.0346 | 0.9678 | 0.9899 | Bacteria | GH |
| dbCAN_3:HMMER | 0.9579 | 0.0409 | 0.9448 | 0.9710 | Bacteria | GH |
| dbCAN_3:DIAMOND | 0.9773 | 0.0324 | 0.9669 | 0.9877 | Bacteria | GH |
| dbCAN_3:eCAMI | 0.9472 | 0.0502 | 0.9312 | 0.9633 | Bacteria | GH |
| dbCAN_4 | 0.9762 | 0.0378 | 0.9641 | 0.9883 | Bacteria | GH |
| dbCAN_4:HMMER | 0.9584 | 0.0405 | 0.9454 | 0.9713 | Bacteria | GH |
| dbCAN_4:DIAMOND | 0.9766 | 0.0361 | 0.9650 | 0.9881 | Bacteria | GH |
| dbCAN_4:dbCAN-sub | 0.9765 | 0.0361 | 0.9649 | 0.9880 | Bacteria | GH |
| CUPP | 0.9555 | 0.0313 | 0.9455 | 0.9655 | Bacteria | GH |
| dbCAN_2 | 0.9656 | 0.0337 | 0.9548 | 0.9763 | Eukaryote | GH |
| dbCAN_2:HMMER | 0.9528 | 0.0247 | 0.9449 | 0.9607 | Eukaryote | GH |
| dbCAN_2:DIAMOND | 0.9676 | 0.0386 | 0.9553 | 0.9800 | Eukaryote | GH |
| dbCAN_2:Hotpep | 0.9219 | 0.0531 | 0.9050 | 0.9389 | Eukaryote | GH |
| dbCAN_3 | 0.9748 | 0.0259 | 0.9666 | 0.9831 | Eukaryote | GH |
| dbCAN_3:HMMER | 0.9619 | 0.0231 | 0.9545 | 0.9692 | Eukaryote | GH |
| dbCAN_3:DIAMOND | 0.9852 | 0.0261 | 0.9768 | 0.9935 | Eukaryote | GH |
| dbCAN_3:eCAMI | 0.9255 | 0.0446 | 0.9113 | 0.9398 | Eukaryote | GH |
| dbCAN_4 | 0.9725 | 0.0218 | 0.9655 | 0.9795 | Eukaryote | GH |
| dbCAN_4:HMMER | 0.9619 | 0.0231 | 0.9545 | 0.9692 | Eukaryote | GH |
| dbCAN_4:DIAMOND | 0.9859 | 0.0230 | 0.9785 | 0.9933 | Eukaryote | GH |
| dbCAN_4:dbCAN-sub | 0.9698 | 0.0215 | 0.9630 | 0.9767 | Eukaryote | GH |
| CUPP | 0.9525 | 0.0275 | 0.9437 | 0.9613 | Eukaryote | GH |
| dbCAN_2 | 0.9550 | 0.0770 | 0.9379 | 0.9721 | All | GT |
| dbCAN_2:HMMER | 0.9498 | 0.0598 | 0.9365 | 0.9631 | All | GT |
| dbCAN_2:DIAMOND | 0.9672 | 0.0821 | 0.9489 | 0.9854 | All | GT |
| dbCAN_2:Hotpep | 0.9031 | 0.0908 | 0.8829 | 0.9233 | All | GT |
| dbCAN_3 | 0.9751 | 0.0585 | 0.9621 | 0.9881 | All | GT |
| dbCAN_3:HMMER | 0.9503 | 0.0597 | 0.9370 | 0.9635 | All | GT |
| dbCAN_3:DIAMOND | 0.9848 | 0.0567 | 0.9722 | 0.9974 | All | GT |
| dbCAN_3:eCAMI | 0.9413 | 0.0822 | 0.9230 | 0.9596 | All | GT |
| dbCAN_4 | 0.9781 | 0.0572 | 0.9654 | 0.9909 | All | GT |
| dbCAN_4:HMMER | 0.9503 | 0.0597 | 0.9370 | 0.9635 | All | GT |
| dbCAN_4:DIAMOND | 0.9838 | 0.0577 | 0.9710 | 0.9966 | All | GT |
| dbCAN_4:dbCAN-sub | 0.9773 | 0.0519 | 0.9657 | 0.9889 | All | GT |
| CUPP | 0.9462 | 0.0579 | 0.9333 | 0.9591 | All | GT |
| dbCAN_2 | 0.9581 | 0.0752 | 0.9340 | 0.9821 | Bacteria | GT |
| dbCAN_2:HMMER | 0.9469 | 0.0757 | 0.9227 | 0.9711 | Bacteria | GT |
| dbCAN_2:DIAMOND | 0.9704 | 0.0804 | 0.9447 | 0.9961 | Bacteria | GT |
| dbCAN_2:Hotpep | 0.8982 | 0.0676 | 0.8766 | 0.9199 | Bacteria | GT |
| dbCAN_3 | 0.9734 | 0.0739 | 0.9497 | 0.9970 | Bacteria | GT |
| dbCAN_3:HMMER | 0.9463 | 0.0752 | 0.9223 | 0.9704 | Bacteria | GT |
| dbCAN_3:DIAMOND | 0.9827 | 0.0721 | 0.9596 | 1.0057 | Bacteria | GT |
| dbCAN_3:eCAMI | 0.9521 | 0.0640 | 0.9317 | 0.9726 | Bacteria | GT |
| dbCAN_4 | 0.9764 | 0.0732 | 0.9530 | 0.9998 | Bacteria | GT |
| dbCAN_4:HMMER | 0.9466 | 0.0753 | 0.9225 | 0.9706 | Bacteria | GT |
| dbCAN_4:DIAMOND | 0.9797 | 0.0738 | 0.9561 | 1.0033 | Bacteria | GT |
| dbCAN_4:dbCAN-sub | 0.9770 | 0.0650 | 0.9562 | 0.9978 | Bacteria | GT |
| CUPP | 0.9602 | 0.0488 | 0.9445 | 0.9758 | Bacteria | GT |
| dbCAN_2 | 0.9520 | 0.0795 | 0.9265 | 0.9774 | Eukaryote | GT |
| dbCAN_2:HMMER | 0.9527 | 0.0386 | 0.9403 | 0.9650 | Eukaryote | GT |
| dbCAN_2:DIAMOND | 0.9639 | 0.0847 | 0.9368 | 0.9910 | Eukaryote | GT |
| dbCAN_2:Hotpep | 0.9079 | 0.1099 | 0.8728 | 0.9430 | Eukaryote | GT |
| dbCAN_3 | 0.9768 | 0.0384 | 0.9646 | 0.9891 | Eukaryote | GT |
| dbCAN_3:HMMER | 0.9542 | 0.0390 | 0.9417 | 0.9667 | Eukaryote | GT |
| dbCAN_3:DIAMOND | 0.9869 | 0.0362 | 0.9754 | 0.9985 | Eukaryote | GT |
| dbCAN_3:eCAMI | 0.9304 | 0.0967 | 0.8995 | 0.9614 | Eukaryote | GT |
| dbCAN_4 | 0.9798 | 0.0354 | 0.9685 | 0.9911 | Eukaryote | GT |
| dbCAN_4:HMMER | 0.9540 | 0.0389 | 0.9415 | 0.9664 | Eukaryote | GT |
| dbCAN_4:DIAMOND | 0.9879 | 0.0354 | 0.9766 | 0.9992 | Eukaryote | GT |
| dbCAN_4:dbCAN-sub | 0.9776 | 0.0352 | 0.9664 | 0.9889 | Eukaryote | GT |
| CUPP | 0.9322 | 0.0633 | 0.9120 | 0.9525 | Eukaryote | GT |
| dbCAN_2 | 0.9959 | 0.0070 | 0.9938 | 0.9979 | All | PL |
| dbCAN_2:HMMER | 0.9963 | 0.0062 | 0.9944 | 0.9981 | All | PL |
| dbCAN_2:DIAMOND | 0.9954 | 0.0073 | 0.9933 | 0.9976 | All | PL |
| dbCAN_2:Hotpep | 0.9929 | 0.0131 | 0.9891 | 0.9968 | All | PL |
| dbCAN_3 | 0.9990 | 0.0030 | 0.9981 | 0.9999 | All | PL |
| dbCAN_3:HMMER | 0.9986 | 0.0035 | 0.9975 | 0.9996 | All | PL |
| dbCAN_3:DIAMOND | 0.9985 | 0.0041 | 0.9973 | 0.9997 | All | PL |
| dbCAN_3:eCAMI | 0.9920 | 0.0129 | 0.9883 | 0.9958 | All | PL |
| dbCAN_4 | 0.9986 | 0.0035 | 0.9975 | 0.9996 | All | PL |
| dbCAN_4:HMMER | 0.9986 | 0.0035 | 0.9975 | 0.9996 | All | PL |
| dbCAN_4:DIAMOND | 0.9988 | 0.0039 | 0.9976 | 0.9999 | All | PL |
| dbCAN_4:dbCAN-sub | 0.9988 | 0.0032 | 0.9978 | 0.9997 | All | PL |
| CUPP | 0.9941 | 0.0096 | 0.9913 | 0.9970 | All | PL |
| dbCAN_2 | 0.9957 | 0.0077 | 0.9928 | 0.9986 | Bacteria | PL |
| dbCAN_2:HMMER | 0.9960 | 0.0067 | 0.9935 | 0.9985 | Bacteria | PL |
| dbCAN_2:DIAMOND | 0.9957 | 0.0077 | 0.9928 | 0.9986 | Bacteria | PL |
| dbCAN_2:Hotpep | 0.9917 | 0.0157 | 0.9859 | 0.9976 | Bacteria | PL |
| dbCAN_3 | 0.9990 | 0.0030 | 0.9979 | 1.0001 | Bacteria | PL |
| dbCAN_3:HMMER | 0.9983 | 0.0038 | 0.9969 | 0.9997 | Bacteria | PL |
| dbCAN_3:DIAMOND | 0.9990 | 0.0030 | 0.9979 | 1.0001 | Bacteria | PL |
| dbCAN_3:eCAMI | 0.9911 | 0.0153 | 0.9854 | 0.9967 | Bacteria | PL |
| dbCAN_4 | 0.9983 | 0.0038 | 0.9969 | 0.9997 | Bacteria | PL |
| dbCAN_4:HMMER | 0.9983 | 0.0038 | 0.9969 | 0.9997 | Bacteria | PL |
| dbCAN_4:DIAMOND | 0.9990 | 0.0030 | 0.9979 | 1.0001 | Bacteria | PL |
| dbCAN_4:dbCAN-sub | 0.9987 | 0.0034 | 0.9974 | 1.0000 | Bacteria | PL |
| CUPP | 0.9930 | 0.0112 | 0.9888 | 0.9972 | Bacteria | PL |
| dbCAN_2 | 0.9962 | 0.0056 | 0.9933 | 0.9990 | Eukaryote | PL |
| dbCAN_2:HMMER | 0.9967 | 0.0055 | 0.9939 | 0.9995 | Eukaryote | PL |
| dbCAN_2:DIAMOND | 0.9950 | 0.0067 | 0.9915 | 0.9984 | Eukaryote | PL |
| dbCAN_2:Hotpep | 0.9950 | 0.0066 | 0.9916 | 0.9984 | Eukaryote | PL |
| dbCAN_3 | 0.9989 | 0.0030 | 0.9974 | 1.0005 | Eukaryote | PL |
| dbCAN_3:HMMER | 0.9989 | 0.0030 | 0.9974 | 1.0005 | Eukaryote | PL |
| dbCAN_3:DIAMOND | 0.9977 | 0.0055 | 0.9948 | 1.0006 | Eukaryote | PL |
| dbCAN_3:eCAMI | 0.9938 | 0.0065 | 0.9905 | 0.9972 | Eukaryote | PL |
| dbCAN_4 | 0.9990 | 0.0029 | 0.9974 | 1.0005 | Eukaryote | PL |
| dbCAN_4:HMMER | 0.9989 | 0.0030 | 0.9974 | 1.0005 | Eukaryote | PL |
| dbCAN_4:DIAMOND | 0.9983 | 0.0052 | 0.9956 | 1.0010 | Eukaryote | PL |
| dbCAN_4:dbCAN-sub | 0.9990 | 0.0029 | 0.9975 | 1.0005 | Eukaryote | PL |
| CUPP | 0.9961 | 0.0056 | 0.9933 | 0.9990 | Eukaryote | PL |
| dbCAN_2 | 0.9893 | 0.0225 | 0.9842 | 0.9945 | All | CE |
| dbCAN_2:HMMER | 0.9901 | 0.0189 | 0.9858 | 0.9945 | All | CE |
| dbCAN_2:DIAMOND | 0.9862 | 0.0242 | 0.9807 | 0.9918 | All | CE |
| dbCAN_2:Hotpep | 0.9821 | 0.0251 | 0.9764 | 0.9878 | All | CE |
| dbCAN_3 | 0.9896 | 0.0220 | 0.9846 | 0.9946 | All | CE |
| dbCAN_3:HMMER | 0.9910 | 0.0177 | 0.9870 | 0.9951 | All | CE |
| dbCAN_3:DIAMOND | 0.9890 | 0.0231 | 0.9837 | 0.9943 | All | CE |
| dbCAN_3:eCAMI | 0.9818 | 0.0249 | 0.9761 | 0.9875 | All | CE |
| dbCAN_4 | 0.9943 | 0.0172 | 0.9904 | 0.9982 | All | CE |
| dbCAN_4:HMMER | 0.9929 | 0.0173 | 0.9889 | 0.9968 | All | CE |
| dbCAN_4:DIAMOND | 0.9919 | 0.0218 | 0.9870 | 0.9969 | All | CE |
| dbCAN_4:dbCAN-sub | 0.9938 | 0.0175 | 0.9898 | 0.9978 | All | CE |
| CUPP | 0.9900 | 0.0187 | 0.9857 | 0.9943 | All | CE |
| dbCAN_2 | 0.9849 | 0.0283 | 0.9758 | 0.9939 | Bacteria | CE |
| dbCAN_2:HMMER | 0.9840 | 0.0239 | 0.9764 | 0.9916 | Bacteria | CE |
| dbCAN_2:DIAMOND | 0.9824 | 0.0282 | 0.9734 | 0.9915 | Bacteria | CE |
| dbCAN_2:Hotpep | 0.9787 | 0.0309 | 0.9688 | 0.9886 | Bacteria | CE |
| dbCAN_3 | 0.9841 | 0.0280 | 0.9752 | 0.9931 | Bacteria | CE |
| dbCAN_3:HMMER | 0.9852 | 0.0224 | 0.9780 | 0.9923 | Bacteria | CE |
| dbCAN_3:DIAMOND | 0.9864 | 0.0268 | 0.9778 | 0.9950 | Bacteria | CE |
| dbCAN_3:eCAMI | 0.9777 | 0.0303 | 0.9680 | 0.9874 | Bacteria | CE |
| dbCAN_4 | 0.9904 | 0.0228 | 0.9831 | 0.9977 | Bacteria | CE |
| dbCAN_4:HMMER | 0.9882 | 0.0225 | 0.9810 | 0.9954 | Bacteria | CE |
| dbCAN_4:DIAMOND | 0.9886 | 0.0263 | 0.9801 | 0.9970 | Bacteria | CE |
| dbCAN_4:dbCAN-sub | 0.9899 | 0.0230 | 0.9826 | 0.9973 | Bacteria | CE |
| CUPP | 0.9852 | 0.0236 | 0.9777 | 0.9927 | Bacteria | CE |
| dbCAN_2 | 0.9943 | 0.0119 | 0.9902 | 0.9983 | Eukaryote | CE |
| dbCAN_2:HMMER | 0.9970 | 0.0062 | 0.9949 | 0.9991 | Eukaryote | CE |
| dbCAN_2:DIAMOND | 0.9905 | 0.0182 | 0.9843 | 0.9966 | Eukaryote | CE |
| dbCAN_2:Hotpep | 0.9859 | 0.0159 | 0.9805 | 0.9913 | Eukaryote | CE |
| dbCAN_3 | 0.9957 | 0.0095 | 0.9924 | 0.9989 | Eukaryote | CE |
| dbCAN_3:HMMER | 0.9975 | 0.0054 | 0.9957 | 0.9994 | Eukaryote | CE |
| dbCAN_3:DIAMOND | 0.9919 | 0.0181 | 0.9858 | 0.9980 | Eukaryote | CE |
| dbCAN_3:eCAMI | 0.9863 | 0.0162 | 0.9808 | 0.9918 | Eukaryote | CE |
| dbCAN_4 | 0.9986 | 0.0041 | 0.9972 | 1.0000 | Eukaryote | CE |
| dbCAN_4:HMMER | 0.9981 | 0.0046 | 0.9965 | 0.9996 | Eukaryote | CE |
| dbCAN_4:DIAMOND | 0.9957 | 0.0147 | 0.9907 | 1.0007 | Eukaryote | CE |
| dbCAN_4:dbCAN-sub | 0.9981 | 0.0055 | 0.9963 | 1.0000 | Eukaryote | CE |
| CUPP | 0.9953 | 0.0086 | 0.9924 | 0.9983 | Eukaryote | CE |
| dbCAN_2 | 0.9856 | 0.0204 | 0.9796 | 0.9915 | All | AA |
| dbCAN_2:HMMER | 0.9856 | 0.0202 | 0.9797 | 0.9914 | All | AA |
| dbCAN_2:DIAMOND | 0.9837 | 0.0212 | 0.9775 | 0.9899 | All | AA |
| dbCAN_2:Hotpep | 0.9827 | 0.0227 | 0.9761 | 0.9893 | All | AA |
| dbCAN_3 | 0.9901 | 0.0188 | 0.9846 | 0.9955 | All | AA |
| dbCAN_3:HMMER | 0.9901 | 0.0196 | 0.9844 | 0.9958 | All | AA |
| dbCAN_3:DIAMOND | 0.9897 | 0.0200 | 0.9839 | 0.9955 | All | AA |
| dbCAN_3:eCAMI | 0.9791 | 0.0233 | 0.9724 | 0.9859 | All | AA |
| dbCAN_4 | 0.9907 | 0.0188 | 0.9853 | 0.9962 | All | AA |
| dbCAN_4:HMMER | 0.9901 | 0.0196 | 0.9844 | 0.9958 | All | AA |
| dbCAN_4:DIAMOND | 0.9897 | 0.0198 | 0.9840 | 0.9954 | All | AA |
| dbCAN_4:dbCAN-sub | 0.9902 | 0.0189 | 0.9847 | 0.9956 | All | AA |
| CUPP | 0.9841 | 0.0215 | 0.9778 | 0.9903 | All | AA |
| dbCAN_2 | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_2:HMMER | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_2:DIAMOND | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_2:Hotpep | 0.9991 | 0.0030 | 0.9971 | 1.0011 | Bacteria | AA |
| dbCAN_3 | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_3:HMMER | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_3:DIAMOND | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_3:eCAMI | 0.9991 | 0.0030 | 0.9971 | 1.0011 | Bacteria | AA |
| dbCAN_4 | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_4:HMMER | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_4:DIAMOND | 0.9991 | 0.0029 | 0.9972 | 1.0011 | Bacteria | AA |
| dbCAN_4:dbCAN-sub | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| CUPP | 1.0000 | 0.0000 | 1.0000 | 1.0000 | Bacteria | AA |
| dbCAN_2 | 0.9813 | 0.0215 | 0.9741 | 0.9884 | Eukaryote | AA |
| dbCAN_2:HMMER | 0.9813 | 0.0212 | 0.9742 | 0.9884 | Eukaryote | AA |
| dbCAN_2:DIAMOND | 0.9789 | 0.0220 | 0.9715 | 0.9862 | Eukaryote | AA |
| dbCAN_2:Hotpep | 0.9778 | 0.0237 | 0.9699 | 0.9857 | Eukaryote | AA |
| dbCAN_3 | 0.9871 | 0.0206 | 0.9803 | 0.9940 | Eukaryote | AA |
| dbCAN_3:HMMER | 0.9872 | 0.0215 | 0.9800 | 0.9943 | Eukaryote | AA |
| dbCAN_3:DIAMOND | 0.9866 | 0.0219 | 0.9793 | 0.9939 | Eukaryote | AA |
| dbCAN_3:eCAMI | 0.9732 | 0.0234 | 0.9654 | 0.9810 | Eukaryote | AA |
| dbCAN_4 | 0.9880 | 0.0207 | 0.9811 | 0.9949 | Eukaryote | AA |
| dbCAN_4:HMMER | 0.9872 | 0.0215 | 0.9800 | 0.9943 | Eukaryote | AA |
| dbCAN_4:DIAMOND | 0.9869 | 0.0217 | 0.9797 | 0.9942 | Eukaryote | AA |
| dbCAN_4:dbCAN-sub | 0.9872 | 0.0207 | 0.9803 | 0.9941 | Eukaryote | AA |
| CUPP | 0.9793 | 0.0225 | 0.9719 | 0.9868 | Eukaryote | AA |
| dbCAN_2 | 0.9656 | 0.0257 | 0.9599 | 0.9713 | All | CBM |
| dbCAN_2:HMMER | 0.9378 | 0.0296 | 0.9312 | 0.9444 | All | CBM |
| dbCAN_2:DIAMOND | 0.9719 | 0.0252 | 0.9663 | 0.9775 | All | CBM |
| dbCAN_2:Hotpep | 0.8823 | 0.0551 | 0.8701 | 0.8946 | All | CBM |
| dbCAN_3 | 0.9718 | 0.0228 | 0.9667 | 0.9768 | All | CBM |
| dbCAN_3:HMMER | 0.9379 | 0.0300 | 0.9313 | 0.9446 | All | CBM |
| dbCAN_3:DIAMOND | 0.9814 | 0.0185 | 0.9773 | 0.9855 | All | CBM |
| dbCAN_3:eCAMI | 0.9267 | 0.0565 | 0.9141 | 0.9392 | All | CBM |
| dbCAN_4 | 0.9763 | 0.0207 | 0.9717 | 0.9809 | All | CBM |
| dbCAN_4:HMMER | 0.9436 | 0.0300 | 0.9370 | 0.9503 | All | CBM |
| dbCAN_4:DIAMOND | 0.9830 | 0.0182 | 0.9790 | 0.9870 | All | CBM |
| dbCAN_4:dbCAN-sub | 0.9761 | 0.0244 | 0.9707 | 0.9816 | All | CBM |
| CUPP | 0.8851 | 0.0851 | 0.8662 | 0.9040 | All | CBM |
| dbCAN_2 | 0.9672 | 0.0266 | 0.9587 | 0.9758 | Bacteria | CBM |
| dbCAN_2:HMMER | 0.9400 | 0.0356 | 0.9286 | 0.9514 | Bacteria | CBM |
| dbCAN_2:DIAMOND | 0.9718 | 0.0240 | 0.9641 | 0.9795 | Bacteria | CBM |
| dbCAN_2:Hotpep | 0.8735 | 0.0634 | 0.8532 | 0.8937 | Bacteria | CBM |
| dbCAN_3 | 0.9707 | 0.0237 | 0.9631 | 0.9783 | Bacteria | CBM |
| dbCAN_3:HMMER | 0.9400 | 0.0364 | 0.9283 | 0.9516 | Bacteria | CBM |
| dbCAN_3:DIAMOND | 0.9760 | 0.0178 | 0.9703 | 0.9817 | Bacteria | CBM |
| dbCAN_3:eCAMI | 0.9171 | 0.0605 | 0.8978 | 0.9365 | Bacteria | CBM |
| dbCAN_4 | 0.9855 | 0.0128 | 0.9814 | 0.9896 | Bacteria | CBM |
| dbCAN_4:HMMER | 0.9494 | 0.0365 | 0.9377 | 0.9611 | Bacteria | CBM |
| dbCAN_4:DIAMOND | 0.9755 | 0.0181 | 0.9697 | 0.9812 | Bacteria | CBM |
| dbCAN_4:dbCAN-sub | 0.9892 | 0.0129 | 0.9851 | 0.9933 | Bacteria | CBM |
| CUPP | 0.8614 | 0.1127 | 0.8253 | 0.8974 | Bacteria | CBM |
| dbCAN_2 | 0.9640 | 0.0250 | 0.9560 | 0.9720 | Eukaryote | CBM |
| dbCAN_2:HMMER | 0.9356 | 0.0223 | 0.9284 | 0.9427 | Eukaryote | CBM |
| dbCAN_2:DIAMOND | 0.9720 | 0.0267 | 0.9635 | 0.9806 | Eukaryote | CBM |
| dbCAN_2:Hotpep | 0.8912 | 0.0445 | 0.8770 | 0.9054 | Eukaryote | CBM |
| dbCAN_3 | 0.9728 | 0.0221 | 0.9658 | 0.9799 | Eukaryote | CBM |
| dbCAN_3:HMMER | 0.9359 | 0.0221 | 0.9288 | 0.9430 | Eukaryote | CBM |
| dbCAN_3:DIAMOND | 0.9869 | 0.0178 | 0.9812 | 0.9926 | Eukaryote | CBM |
| dbCAN_3:eCAMI | 0.9362 | 0.0512 | 0.9198 | 0.9526 | Eukaryote | CBM |
| dbCAN_4 | 0.9672 | 0.0230 | 0.9598 | 0.9745 | Eukaryote | CBM |
| dbCAN_4:HMMER | 0.9379 | 0.0205 | 0.9313 | 0.9444 | Eukaryote | CBM |
| dbCAN_4:DIAMOND | 0.9905 | 0.0150 | 0.9857 | 0.9953 | Eukaryote | CBM |
| dbCAN_4:dbCAN-sub | 0.9631 | 0.0262 | 0.9547 | 0.9715 | Eukaryote | CBM |
| CUPP | 0.9088 | 0.0286 | 0.8997 | 0.9180 | Eukaryote | CBM |
## png
## 2
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## 2
| Prediction_tool | Lower CI | Mean | Upper CI | Standard Deviation | Tax_group |
|---|---|---|---|---|---|
| dbCAN_2 | 0.9755 | 0.9769 | 0.9782 | 0.0855 | All |
| dbCAN_2:HMMER | 0.9679 | 0.9694 | 0.9709 | 0.0969 | All |
| dbCAN_2:DIAMOND | 0.9778 | 0.9791 | 0.9804 | 0.0821 | All |
| dbCAN_2:Hotpep | 0.9445 | 0.9464 | 0.9483 | 0.1248 | All |
| dbCAN_3 | 0.9828 | 0.9839 | 0.9850 | 0.0721 | All |
| dbCAN_3:HMMER | 0.9699 | 0.9714 | 0.9728 | 0.0939 | All |
| dbCAN_3:DIAMOND | 0.9865 | 0.9875 | 0.9885 | 0.0643 | All |
| dbCAN_3:eCAMI | 0.9593 | 0.9610 | 0.9627 | 0.1092 | All |
| dbCAN_4 | 0.9845 | 0.9856 | 0.9866 | 0.0683 | All |
| dbCAN_4:HMMER | 0.9712 | 0.9727 | 0.9741 | 0.0920 | All |
| dbCAN_4:DIAMOND | 0.9871 | 0.9880 | 0.9890 | 0.0627 | All |
| dbCAN_4:dbCAN-sub | 0.9840 | 0.9851 | 0.9861 | 0.0694 | All |
| CUPP | 0.9580 | 0.9597 | 0.9614 | 0.1093 | All |
| dbCAN_2 | 0.9766 | 0.9784 | 0.9802 | 0.0825 | Bacteria |
| dbCAN_2:HMMER | 0.9679 | 0.9700 | 0.9721 | 0.0958 | Bacteria |
| dbCAN_2:DIAMOND | 0.9784 | 0.9802 | 0.9819 | 0.0801 | Bacteria |
| dbCAN_2:Hotpep | 0.9438 | 0.9466 | 0.9493 | 0.1249 | Bacteria |
| dbCAN_3 | 0.9825 | 0.9840 | 0.9856 | 0.0716 | Bacteria |
| dbCAN_3:HMMER | 0.9690 | 0.9710 | 0.9731 | 0.0944 | Bacteria |
| dbCAN_3:DIAMOND | 0.9853 | 0.9867 | 0.9882 | 0.0662 | Bacteria |
| dbCAN_3:eCAMI | 0.9619 | 0.9642 | 0.9666 | 0.1054 | Bacteria |
| dbCAN_4 | 0.9863 | 0.9877 | 0.9891 | 0.0632 | Bacteria |
| dbCAN_4:HMMER | 0.9712 | 0.9732 | 0.9752 | 0.0911 | Bacteria |
| dbCAN_4:DIAMOND | 0.9848 | 0.9863 | 0.9877 | 0.0669 | Bacteria |
| dbCAN_4:dbCAN-sub | 0.9870 | 0.9884 | 0.9897 | 0.0614 | Bacteria |
| CUPP | 0.9568 | 0.9592 | 0.9616 | 0.1101 | Bacteria |
| dbCAN_2 | 0.9734 | 0.9753 | 0.9772 | 0.0885 | Eukaryote |
| dbCAN_2:HMMER | 0.9666 | 0.9688 | 0.9709 | 0.0979 | Eukaryote |
| dbCAN_2:DIAMOND | 0.9762 | 0.9781 | 0.9799 | 0.0840 | Eukaryote |
| dbCAN_2:Hotpep | 0.9435 | 0.9462 | 0.9490 | 0.1248 | Eukaryote |
| dbCAN_3 | 0.9822 | 0.9838 | 0.9854 | 0.0725 | Eukaryote |
| dbCAN_3:HMMER | 0.9697 | 0.9717 | 0.9737 | 0.0934 | Eukaryote |
| dbCAN_3:DIAMOND | 0.9869 | 0.9883 | 0.9896 | 0.0624 | Eukaryote |
| dbCAN_3:eCAMI | 0.9553 | 0.9577 | 0.9602 | 0.1128 | Eukaryote |
| dbCAN_4 | 0.9819 | 0.9835 | 0.9851 | 0.0730 | Eukaryote |
| dbCAN_4:HMMER | 0.9701 | 0.9721 | 0.9741 | 0.0930 | Eukaryote |
| dbCAN_4:DIAMOND | 0.9886 | 0.9898 | 0.9911 | 0.0582 | Eukaryote |
| dbCAN_4:dbCAN-sub | 0.9801 | 0.9817 | 0.9834 | 0.0765 | Eukaryote |
| CUPP | 0.9578 | 0.9602 | 0.9625 | 0.1086 | Eukaryote |
pdf(file = "../report/cazy_class_classification/multilabel_classification/cazyClassMLC.RI.ci.pdf", width = 8.23, height = 5)
p.ri.class.tax.ci
dev.off()
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pdf(file = "../report/cazy_class_classification/multilabel_classification/cazyClassMLC.ARI.ci.pdf", width = 8.23, height = 5)
p.ari.class.tax.ci
dev.off()
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The following section evaluates the performance of the CAZyme classifiers to predict CAZy family classifications.
Below is a table summarising the overall CAZy family classifications for across all CAZy families, when pooling all test sets.
| Classifier | Spec Mean | Spec Standard Deviation | Spec Lower CI | Spec Upper CI | Sens Mean | Sens Standard Deviation | Sens Lower CI | Sens Upper CI | Prec Mean | Prec Standard Deviation | Prec Lower CI | Prec Upper CI | F1-score Mean | F1-score Standard Deviation | F1-score Lower CI | F1-score Upper CI | Acc Mean | Acc Standard Deviation | Acc Lower CI | Acc Upper CI |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CUPP | 0.9999 | 3e-04 | 0.9999 | 1.0000 | 0.6422 | 0.4389 | 0.5940 | 0.6904 | 0.6793 | 0.4519 | 0.6297 | 0.7290 | 0.6511 | 0.4385 | 0.6029 | 0.6992 | 0.9992 | 0.0021 | 0.9990 | 0.9994 |
| dbCAN_2 | 0.9999 | 4e-04 | 0.9999 | 0.9999 | 0.8388 | 0.2944 | 0.8065 | 0.8710 | 0.8760 | 0.2971 | 0.8435 | 0.9085 | 0.8458 | 0.2921 | 0.8139 | 0.8778 | 0.9995 | 0.0014 | 0.9993 | 0.9996 |
| dbCAN_2:DIAMOND | 0.9999 | 4e-04 | 0.9998 | 0.9999 | 0.8447 | 0.2887 | 0.8131 | 0.8763 | 0.8736 | 0.2891 | 0.8420 | 0.9053 | 0.8497 | 0.2845 | 0.8185 | 0.8808 | 0.9996 | 0.0010 | 0.9994 | 0.9997 |
| dbCAN_2:HMMER | 0.9999 | 3e-04 | 0.9998 | 0.9999 | 0.8136 | 0.3417 | 0.7766 | 0.8506 | 0.8292 | 0.3404 | 0.7924 | 0.8661 | 0.8080 | 0.3374 | 0.7714 | 0.8445 | 0.9993 | 0.0019 | 0.9991 | 0.9996 |
| dbCAN_2:Hotpep | 0.9994 | 2e-03 | 0.9992 | 0.9996 | 0.7287 | 0.3526 | 0.6910 | 0.7664 | 0.7232 | 0.3959 | 0.6808 | 0.7655 | 0.6957 | 0.3664 | 0.6565 | 0.7349 | 0.9987 | 0.0032 | 0.9984 | 0.9991 |
| dbCAN_3 | 0.9999 | 3e-04 | 0.9999 | 0.9999 | 0.9050 | 0.2360 | 0.8791 | 0.9308 | 0.9141 | 0.2404 | 0.8877 | 0.9405 | 0.9014 | 0.2350 | 0.8757 | 0.9272 | 0.9996 | 0.0010 | 0.9995 | 0.9998 |
| dbCAN_3:DIAMOND | 0.9999 | 4e-04 | 0.9998 | 0.9999 | 0.9298 | 0.2086 | 0.9069 | 0.9527 | 0.9133 | 0.2227 | 0.8889 | 0.9378 | 0.9157 | 0.2121 | 0.8924 | 0.9389 | 0.9997 | 0.0007 | 0.9996 | 0.9998 |
| dbCAN_3:eCAMI | 0.9997 | 1e-03 | 0.9996 | 0.9998 | 0.7013 | 0.3611 | 0.6624 | 0.7401 | 0.7378 | 0.3890 | 0.6959 | 0.7796 | 0.6976 | 0.3642 | 0.6584 | 0.7368 | 0.9992 | 0.0017 | 0.9990 | 0.9993 |
| dbCAN_3:HMMER | 0.9999 | 4e-04 | 0.9998 | 0.9999 | 0.8512 | 0.3052 | 0.8181 | 0.8844 | 0.8629 | 0.3017 | 0.8301 | 0.8957 | 0.8435 | 0.3009 | 0.8108 | 0.8761 | 0.9994 | 0.0019 | 0.9992 | 0.9996 |
| dbCAN_4 | 0.9999 | 3e-04 | 0.9999 | 0.9999 | 0.9001 | 0.2615 | 0.8716 | 0.9286 | 0.8906 | 0.2705 | 0.8612 | 0.9201 | 0.8856 | 0.2636 | 0.8569 | 0.9143 | 0.9996 | 0.0012 | 0.9995 | 0.9998 |
| dbCAN_4:dbCAN-sub | 0.9999 | 4e-04 | 0.9998 | 0.9999 | 0.8905 | 0.2722 | 0.8609 | 0.9201 | 0.8811 | 0.2802 | 0.8506 | 0.9116 | 0.8750 | 0.2736 | 0.8452 | 0.9047 | 0.9996 | 0.0012 | 0.9995 | 0.9998 |
| dbCAN_4:DIAMOND | 0.9999 | 3e-04 | 0.9998 | 0.9999 | 0.9379 | 0.1941 | 0.9166 | 0.9591 | 0.9231 | 0.2059 | 0.9005 | 0.9457 | 0.9229 | 0.1985 | 0.9012 | 0.9447 | 0.9997 | 0.0007 | 0.9997 | 0.9998 |
| dbCAN_4:HMMER | 0.9999 | 4e-04 | 0.9998 | 0.9999 | 0.8576 | 0.2976 | 0.8253 | 0.8898 | 0.8695 | 0.2934 | 0.8377 | 0.9013 | 0.8501 | 0.2933 | 0.8183 | 0.8819 | 0.9994 | 0.0019 | 0.9992 | 0.9996 |
Here we plot the 95% confidence intervals for CAZy class classification, when pooling all CAZy classes and test sets.
Figure 10.1: Summary statistics of CAZyme classifiers performances of CAZy family classification, plotting the mean plus and minus the 95% confidence interval.
To evaluate the overall performance of each classifier, for each CAZy family, the F1-score was calculated for every family. Families were grouped by their parent CAZy class and the distribution of the F1-scores is shown in figure 10.2.
Figure 10.2: Proportaional area plot of F1-score per CAZy distribution per CAZy class.
10.2 Below is a table displaying the number of test sets in which each CAZy class was present, and were used to draw the proporitonal areas for each class in figure10.2.
| Prediction_tool | GH | GT | PL | CE | AA | CBM |
|---|---|---|---|---|---|---|
| dbCAN_2 | 136 | 75 | 23 | 18 | 16 | 55 |
| dbCAN_2:HMMER | 140 | 76 | 23 | 19 | 16 | 56 |
| dbCAN_2:DIAMOND | 136 | 75 | 23 | 18 | 16 | 55 |
| dbCAN_2:Hotpep | 137 | 75 | 24 | 17 | 16 | 69 |
| dbCAN_3 | 135 | 76 | 23 | 17 | 16 | 55 |
| dbCAN_3:HMMER | 139 | 76 | 23 | 18 | 16 | 56 |
| dbCAN_3:DIAMOND | 135 | 76 | 23 | 17 | 16 | 55 |
| dbCAN_3:eCAMI | 137 | 76 | 23 | 17 | 16 | 65 |
| dbCAN_4 | 137 | 76 | 23 | 18 | 16 | 56 |
| dbCAN_4:HMMER | 139 | 77 | 23 | 18 | 16 | 56 |
| dbCAN_4:DIAMOND | 135 | 76 | 23 | 17 | 16 | 55 |
| dbCAN_4:dbCAN-sub | 138 | 76 | 23 | 18 | 16 | 56 |
| CUPP | 135 | 75 | 23 | 17 | 16 | 55 |
To evaluate the performance of predicting each CAZy family independent of all other CAZy families, the sensitivity and precision for each CAZy family, for each CAZyme classifier was calculated and plotted against each other (Fig.??). Whereas sensitivity was plotted against sensitivity for CAZy classes, owing to the extremely small variation in specificity scores, sensitivity was plotted as a percentage against log10 of the specificity percentage.
The following plots present the specificity (Fig.10.4), sensitivity (Fig.10.6), precision (Fig.10.8), F1-score (Fig.10.10) and accuracy (Fig.10.12) for each CAZy family per classifier. In accompaniment to each plot is a table summarising the mean statistic value for each classifier across all CAZy families for each CAZy class.
| CAZy_class | Prediction_tool | Mean | Standard Deviation | Lower CI | Upper CI |
|---|---|---|---|---|---|
| GH | dbCAN_2 | 0.9999 | 0.0002 | 0.9999 | 1.0000 |
| GH | dbCAN_2:HMMER | 0.9999 | 0.0002 | 0.9999 | 1.0000 |
| GH | dbCAN_2:DIAMOND | 0.9999 | 0.0003 | 0.9999 | 1.0000 |
| GH | dbCAN_2:Hotpep | 0.9998 | 0.0006 | 0.9998 | 0.9999 |
| GH | dbCAN_3 | 0.9999 | 0.0002 | 0.9999 | 1.0000 |
| GH | dbCAN_3:HMMER | 0.9999 | 0.0001 | 0.9999 | 1.0000 |
| GH | dbCAN_3:DIAMOND | 0.9999 | 0.0003 | 0.9999 | 1.0000 |
| GH | dbCAN_3:eCAMI | 0.9999 | 0.0004 | 0.9998 | 1.0000 |
| GH | dbCAN_4 | 1.0000 | 0.0001 | 0.9999 | 1.0000 |
| GH | dbCAN_4:HMMER | 0.9999 | 0.0001 | 0.9999 | 1.0000 |
| GH | dbCAN_4:DIAMOND | 0.9999 | 0.0002 | 0.9999 | 1.0000 |
| GH | dbCAN_4:dbCAN-sub | 0.9999 | 0.0002 | 0.9999 | 1.0000 |
| GH | CUPP | 0.9999 | 0.0002 | 0.9999 | 1.0000 |
| GT | dbCAN_2 | 0.9999 | 0.0002 | 0.9999 | 1.0000 |
| GT | dbCAN_2:HMMER | 0.9999 | 0.0003 | 0.9998 | 0.9999 |
| GT | dbCAN_2:DIAMOND | 0.9999 | 0.0003 | 0.9998 | 1.0000 |
| GT | dbCAN_2:Hotpep | 0.9999 | 0.0002 | 0.9998 | 1.0000 |
| GT | dbCAN_3 | 0.9999 | 0.0002 | 0.9998 | 1.0000 |
| GT | dbCAN_3:HMMER | 0.9999 | 0.0003 | 0.9998 | 0.9999 |
| GT | dbCAN_3:DIAMOND | 0.9999 | 0.0003 | 0.9998 | 0.9999 |
| GT | dbCAN_3:eCAMI | 0.9999 | 0.0002 | 0.9998 | 1.0000 |
| GT | dbCAN_4 | 0.9999 | 0.0003 | 0.9998 | 0.9999 |
| GT | dbCAN_4:HMMER | 0.9999 | 0.0003 | 0.9998 | 0.9999 |
| GT | dbCAN_4:DIAMOND | 0.9999 | 0.0003 | 0.9998 | 0.9999 |
| GT | dbCAN_4:dbCAN-sub | 0.9998 | 0.0003 | 0.9998 | 0.9999 |
| GT | CUPP | 0.9999 | 0.0002 | 0.9999 | 1.0000 |
| PL | dbCAN_2 | 1.0000 | 0.0000 | 1.0000 | 1.0000 |
| PL | dbCAN_2:HMMER | 1.0000 | 0.0000 | 1.0000 | 1.0000 |
| PL | dbCAN_2:DIAMOND | 1.0000 | 0.0000 | 1.0000 | 1.0000 |
| PL | dbCAN_2:Hotpep | 1.0000 | 0.0001 | 1.0000 | 1.0000 |
| PL | dbCAN_3 | 1.0000 | 0.0000 | 1.0000 | 1.0000 |
| PL | dbCAN_3:HMMER | 1.0000 | 0.0000 | 1.0000 | 1.0000 |
| PL | dbCAN_3:DIAMOND | 1.0000 | 0.0001 | 0.9999 | 1.0000 |
| PL | dbCAN_3:eCAMI | 1.0000 | 0.0001 | 0.9999 | 1.0000 |
| PL | dbCAN_4 | 1.0000 | 0.0000 | 1.0000 | 1.0000 |
| PL | dbCAN_4:HMMER | 1.0000 | 0.0000 | 1.0000 | 1.0000 |
| PL | dbCAN_4:DIAMOND | 1.0000 | 0.0001 | 0.9999 | 1.0000 |
| PL | dbCAN_4:dbCAN-sub | 1.0000 | 0.0000 | 1.0000 | 1.0000 |
| PL | CUPP | 1.0000 | 0.0000 | 1.0000 | 1.0000 |
| CE | dbCAN_2 | 0.9995 | 0.0010 | 0.9990 | 1.0000 |
| CE | dbCAN_2:HMMER | 0.9996 | 0.0009 | 0.9991 | 1.0000 |
| CE | dbCAN_2:DIAMOND | 0.9996 | 0.0010 | 0.9991 | 1.0001 |
| CE | dbCAN_2:Hotpep | 0.9994 | 0.0011 | 0.9988 | 0.9999 |
| CE | dbCAN_3 | 0.9995 | 0.0010 | 0.9990 | 1.0001 |
| CE | dbCAN_3:HMMER | 0.9996 | 0.0009 | 0.9991 | 1.0000 |
| CE | dbCAN_3:DIAMOND | 0.9995 | 0.0008 | 0.9991 | 0.9999 |
| CE | dbCAN_3:eCAMI | 0.9995 | 0.0010 | 0.9990 | 1.0000 |
| CE | dbCAN_4 | 0.9996 | 0.0009 | 0.9991 | 1.0000 |
| CE | dbCAN_4:HMMER | 0.9996 | 0.0009 | 0.9991 | 1.0000 |
| CE | dbCAN_4:DIAMOND | 0.9996 | 0.0009 | 0.9991 | 1.0000 |
| CE | dbCAN_4:dbCAN-sub | 0.9996 | 0.0009 | 0.9991 | 1.0000 |
| CE | CUPP | 0.9996 | 0.0009 | 0.9991 | 1.0001 |
| AA | dbCAN_2 | 0.9997 | 0.0006 | 0.9994 | 1.0000 |
| AA | dbCAN_2:HMMER | 0.9997 | 0.0006 | 0.9994 | 1.0000 |
| AA | dbCAN_2:DIAMOND | 0.9997 | 0.0006 | 0.9994 | 1.0000 |
| AA | dbCAN_2:Hotpep | 0.9997 | 0.0006 | 0.9993 | 1.0000 |
| AA | dbCAN_3 | 0.9997 | 0.0006 | 0.9993 | 1.0000 |
| AA | dbCAN_3:HMMER | 0.9996 | 0.0007 | 0.9993 | 1.0000 |
| AA | dbCAN_3:DIAMOND | 0.9996 | 0.0006 | 0.9993 | 0.9999 |
| AA | dbCAN_3:eCAMI | 0.9997 | 0.0006 | 0.9994 | 1.0000 |
| AA | dbCAN_4 | 0.9996 | 0.0007 | 0.9993 | 1.0000 |
| AA | dbCAN_4:HMMER | 0.9996 | 0.0007 | 0.9993 | 1.0000 |
| AA | dbCAN_4:DIAMOND | 0.9996 | 0.0006 | 0.9993 | 0.9999 |
| AA | dbCAN_4:dbCAN-sub | 0.9996 | 0.0007 | 0.9993 | 1.0000 |
| AA | CUPP | 0.9997 | 0.0007 | 0.9993 | 1.0000 |
| CBM | dbCAN_2 | 0.9999 | 0.0003 | 0.9998 | 0.9999 |
| CBM | dbCAN_2:HMMER | 0.9999 | 0.0004 | 0.9998 | 1.0000 |
| CBM | dbCAN_2:DIAMOND | 0.9998 | 0.0003 | 0.9997 | 0.9999 |
| CBM | dbCAN_2:Hotpep | 0.9976 | 0.0039 | 0.9966 | 0.9985 |
| CBM | dbCAN_3 | 0.9999 | 0.0002 | 0.9999 | 1.0000 |
| CBM | dbCAN_3:HMMER | 0.9999 | 0.0004 | 0.9998 | 1.0000 |
| CBM | dbCAN_3:DIAMOND | 0.9999 | 0.0002 | 0.9998 | 0.9999 |
| CBM | dbCAN_3:eCAMI | 0.9989 | 0.0018 | 0.9985 | 0.9994 |
| CBM | dbCAN_4 | 0.9999 | 0.0004 | 0.9998 | 1.0000 |
| CBM | dbCAN_4:HMMER | 0.9999 | 0.0004 | 0.9998 | 1.0000 |
| CBM | dbCAN_4:DIAMOND | 0.9999 | 0.0002 | 0.9998 | 0.9999 |
| CBM | dbCAN_4:dbCAN-sub | 0.9998 | 0.0005 | 0.9997 | 1.0000 |
| CBM | CUPP | 1.0000 | 0.0000 | 1.0000 | 1.0000 |
Figure 10.3: 95% confidence intervals of the specificity of CAZy family classification across all CAZy families per CAZy class, for each CAZyme classifier.
Figure 10.4: Scatter plot of overlaying a one-dimensional box-and-whisker plot of specificity for each CAZy family for each CAZyme classifier. Each CAZy family is represented as a single point on the plot.
| CAZy_class | Prediction_tool | Mean | Standard Deviation | Lower CI | Upper CI |
|---|---|---|---|---|---|
| GH | dbCAN_2 | 0.8667 | 0.2703 | 0.8208 | 0.9125 |
| GH | dbCAN_2:HMMER | 0.8483 | 0.3135 | 0.7960 | 0.9007 |
| GH | dbCAN_2:DIAMOND | 0.8680 | 0.2700 | 0.8222 | 0.9138 |
| GH | dbCAN_2:Hotpep | 0.7820 | 0.3204 | 0.7279 | 0.8361 |
| GH | dbCAN_3 | 0.9282 | 0.2007 | 0.8940 | 0.9623 |
| GH | dbCAN_3:HMMER | 0.8796 | 0.2785 | 0.8329 | 0.9263 |
| GH | dbCAN_3:DIAMOND | 0.9440 | 0.1931 | 0.9111 | 0.9768 |
| GH | dbCAN_3:eCAMI | 0.7257 | 0.3538 | 0.6659 | 0.7854 |
| GH | dbCAN_4 | 0.9197 | 0.2355 | 0.8799 | 0.9595 |
| GH | dbCAN_4:HMMER | 0.8868 | 0.2684 | 0.8418 | 0.9318 |
| GH | dbCAN_4:DIAMOND | 0.9489 | 0.1753 | 0.9191 | 0.9787 |
| GH | dbCAN_4:dbCAN-sub | 0.9096 | 0.2496 | 0.8676 | 0.9516 |
| GH | CUPP | 0.7845 | 0.3643 | 0.7225 | 0.8465 |
| GT | dbCAN_2 | 0.8588 | 0.2654 | 0.7977 | 0.9199 |
| GT | dbCAN_2:HMMER | 0.8430 | 0.3035 | 0.7736 | 0.9123 |
| GT | dbCAN_2:DIAMOND | 0.8717 | 0.2586 | 0.8122 | 0.9312 |
| GT | dbCAN_2:Hotpep | 0.7796 | 0.3189 | 0.7062 | 0.8529 |
| GT | dbCAN_3 | 0.9008 | 0.2261 | 0.8491 | 0.9524 |
| GT | dbCAN_3:HMMER | 0.8759 | 0.2546 | 0.8177 | 0.9341 |
| GT | dbCAN_3:DIAMOND | 0.9354 | 0.1866 | 0.8927 | 0.9780 |
| GT | dbCAN_3:eCAMI | 0.7749 | 0.3195 | 0.7019 | 0.8479 |
| GT | dbCAN_4 | 0.9103 | 0.2389 | 0.8557 | 0.9649 |
| GT | dbCAN_4:HMMER | 0.8644 | 0.2718 | 0.8027 | 0.9261 |
| GT | dbCAN_4:DIAMOND | 0.9360 | 0.1867 | 0.8933 | 0.9787 |
| GT | dbCAN_4:dbCAN-sub | 0.9105 | 0.2391 | 0.8558 | 0.9651 |
| GT | CUPP | 0.8039 | 0.2981 | 0.7354 | 0.8725 |
| PL | dbCAN_2 | 0.8076 | 0.3448 | 0.6585 | 0.9568 |
| PL | dbCAN_2:HMMER | 0.8363 | 0.3501 | 0.6849 | 0.9877 |
| PL | dbCAN_2:DIAMOND | 0.8477 | 0.3415 | 0.7000 | 0.9953 |
| PL | dbCAN_2:Hotpep | 0.6951 | 0.3647 | 0.5411 | 0.8491 |
| PL | dbCAN_3 | 0.9558 | 0.2084 | 0.8657 | 1.0459 |
| PL | dbCAN_3:HMMER | 0.9232 | 0.2313 | 0.8232 | 1.0233 |
| PL | dbCAN_3:DIAMOND | 0.9752 | 0.1043 | 0.9301 | 1.0202 |
| PL | dbCAN_3:eCAMI | 0.6599 | 0.3942 | 0.4894 | 0.8303 |
| PL | dbCAN_4 | 0.9232 | 0.2313 | 0.8232 | 1.0233 |
| PL | dbCAN_4:HMMER | 0.9232 | 0.2313 | 0.8232 | 1.0233 |
| PL | dbCAN_4:DIAMOND | 0.9776 | 0.1042 | 0.9325 | 1.0226 |
| PL | dbCAN_4:dbCAN-sub | 0.9239 | 0.2315 | 0.8238 | 1.0240 |
| PL | CUPP | 0.7051 | 0.4164 | 0.5251 | 0.8852 |
| CE | dbCAN_2 | 0.7329 | 0.3820 | 0.5429 | 0.9228 |
| CE | dbCAN_2:HMMER | 0.7161 | 0.4409 | 0.5036 | 0.9286 |
| CE | dbCAN_2:DIAMOND | 0.6889 | 0.3601 | 0.5098 | 0.8679 |
| CE | dbCAN_2:Hotpep | 0.7114 | 0.3473 | 0.5328 | 0.8899 |
| CE | dbCAN_3 | 0.8505 | 0.2923 | 0.7002 | 1.0008 |
| CE | dbCAN_3:HMMER | 0.8114 | 0.3750 | 0.6249 | 0.9979 |
| CE | dbCAN_3:DIAMOND | 0.8806 | 0.2384 | 0.7580 | 1.0032 |
| CE | dbCAN_3:eCAMI | 0.6539 | 0.3210 | 0.4888 | 0.8190 |
| CE | dbCAN_4 | 0.8773 | 0.3199 | 0.7182 | 1.0364 |
| CE | dbCAN_4:HMMER | 0.8670 | 0.3173 | 0.7091 | 1.0248 |
| CE | dbCAN_4:DIAMOND | 0.9706 | 0.0472 | 0.9463 | 0.9949 |
| CE | dbCAN_4:dbCAN-sub | 0.8787 | 0.3204 | 0.7193 | 1.0380 |
| CE | CUPP | 0.7414 | 0.4256 | 0.5226 | 0.9602 |
| AA | dbCAN_2 | 0.7706 | 0.3323 | 0.5935 | 0.9476 |
| AA | dbCAN_2:HMMER | 0.8640 | 0.2657 | 0.7224 | 1.0056 |
| AA | dbCAN_2:DIAMOND | 0.7751 | 0.2804 | 0.6256 | 0.9245 |
| AA | dbCAN_2:Hotpep | 0.7104 | 0.3702 | 0.5132 | 0.9077 |
| AA | dbCAN_3 | 0.9142 | 0.2496 | 0.7813 | 1.0472 |
| AA | dbCAN_3:HMMER | 0.9085 | 0.2565 | 0.7718 | 1.0452 |
| AA | dbCAN_3:DIAMOND | 0.9517 | 0.1079 | 0.8942 | 1.0092 |
| AA | dbCAN_3:eCAMI | 0.6443 | 0.3966 | 0.4329 | 0.8556 |
| AA | dbCAN_4 | 0.9102 | 0.2570 | 0.7732 | 1.0471 |
| AA | dbCAN_4:HMMER | 0.9085 | 0.2565 | 0.7718 | 1.0452 |
| AA | dbCAN_4:DIAMOND | 0.9567 | 0.1038 | 0.9014 | 1.0120 |
| AA | dbCAN_4:dbCAN-sub | 0.9093 | 0.2567 | 0.7725 | 1.0461 |
| AA | CUPP | 0.6941 | 0.4385 | 0.4604 | 0.9277 |
| CBM | dbCAN_2 | 0.8099 | 0.3219 | 0.7228 | 0.8969 |
| CBM | dbCAN_2:HMMER | 0.6965 | 0.4123 | 0.5861 | 0.8069 |
| CBM | dbCAN_2:DIAMOND | 0.8203 | 0.3169 | 0.7346 | 0.9060 |
| CBM | dbCAN_2:Hotpep | 0.5879 | 0.4090 | 0.4896 | 0.6861 |
| CBM | dbCAN_3 | 0.8467 | 0.3046 | 0.7643 | 0.9290 |
| CBM | dbCAN_3:HMMER | 0.7143 | 0.4032 | 0.6064 | 0.8223 |
| CBM | dbCAN_3:DIAMOND | 0.8772 | 0.2968 | 0.7969 | 0.9574 |
| CBM | dbCAN_3:eCAMI | 0.6048 | 0.3972 | 0.5064 | 0.7033 |
| CBM | dbCAN_4 | 0.8332 | 0.3345 | 0.7436 | 0.9228 |
| CBM | dbCAN_4:HMMER | 0.7311 | 0.3923 | 0.6261 | 0.8362 |
| CBM | dbCAN_4:DIAMOND | 0.8811 | 0.2943 | 0.8016 | 0.9607 |
| CBM | dbCAN_4:dbCAN-sub | 0.8012 | 0.3530 | 0.7066 | 0.8957 |
| CBM | CUPP | 0.0000 | 0.0000 | 0.0000 | 0.0000 |
Figure 10.5: 95% confidence intervals of the sensitivity of CAZy family classification across all CAZy families per CAZy class, for each CAZyme classifier.
Figure 10.6: Scatter plot of overlaying a one-dimensional box-and-whisker plot of sensitivity for each CAZy family for each CAZyme classifier. Each CAZy family is represented as a single point on the plot.
| CAZy_class | Prediction_tool | Mean | Standard Deviation | Lower CI | Upper CI |
|---|---|---|---|---|---|
| GH | dbCAN_2 | 0.9190 | 0.2615 | 0.8747 | 0.9634 |
| GH | dbCAN_2:HMMER | 0.8746 | 0.3110 | 0.8227 | 0.9266 |
| GH | dbCAN_2:DIAMOND | 0.9125 | 0.2620 | 0.8681 | 0.9569 |
| GH | dbCAN_2:Hotpep | 0.8549 | 0.3239 | 0.8002 | 0.9097 |
| GH | dbCAN_3 | 0.9533 | 0.1913 | 0.9207 | 0.9858 |
| GH | dbCAN_3:HMMER | 0.9030 | 0.2736 | 0.8571 | 0.9489 |
| GH | dbCAN_3:DIAMOND | 0.9443 | 0.1936 | 0.9114 | 0.9773 |
| GH | dbCAN_3:eCAMI | 0.8186 | 0.3655 | 0.7568 | 0.8803 |
| GH | dbCAN_4 | 0.9245 | 0.2397 | 0.8840 | 0.9650 |
| GH | dbCAN_4:HMMER | 0.9102 | 0.2626 | 0.8662 | 0.9543 |
| GH | dbCAN_4:DIAMOND | 0.9509 | 0.1762 | 0.9209 | 0.9809 |
| GH | dbCAN_4:dbCAN-sub | 0.9127 | 0.2535 | 0.8700 | 0.9553 |
| GH | CUPP | 0.8331 | 0.3615 | 0.7715 | 0.8946 |
| GT | dbCAN_2 | 0.9099 | 0.2523 | 0.8519 | 0.9680 |
| GT | dbCAN_2:HMMER | 0.8431 | 0.3071 | 0.7729 | 0.9133 |
| GT | dbCAN_2:DIAMOND | 0.9095 | 0.2522 | 0.8515 | 0.9676 |
| GT | dbCAN_2:Hotpep | 0.8627 | 0.3094 | 0.7915 | 0.9339 |
| GT | dbCAN_3 | 0.9240 | 0.2266 | 0.8722 | 0.9758 |
| GT | dbCAN_3:HMMER | 0.8760 | 0.2588 | 0.8168 | 0.9351 |
| GT | dbCAN_3:DIAMOND | 0.9356 | 0.1990 | 0.8901 | 0.9811 |
| GT | dbCAN_3:eCAMI | 0.8668 | 0.3066 | 0.7967 | 0.9368 |
| GT | dbCAN_4 | 0.8953 | 0.2508 | 0.8380 | 0.9526 |
| GT | dbCAN_4:HMMER | 0.8646 | 0.2758 | 0.8020 | 0.9272 |
| GT | dbCAN_4:DIAMOND | 0.9360 | 0.1985 | 0.8907 | 0.9814 |
| GT | dbCAN_4:dbCAN-sub | 0.8940 | 0.2511 | 0.8366 | 0.9513 |
| GT | CUPP | 0.8785 | 0.2933 | 0.8110 | 0.9460 |
| PL | dbCAN_2 | 0.8689 | 0.3441 | 0.7201 | 1.0176 |
| PL | dbCAN_2:HMMER | 0.8471 | 0.3512 | 0.6953 | 0.9990 |
| PL | dbCAN_2:DIAMOND | 0.8544 | 0.3453 | 0.7050 | 1.0037 |
| PL | dbCAN_2:Hotpep | 0.8326 | 0.3804 | 0.6720 | 0.9933 |
| PL | dbCAN_3 | 0.9210 | 0.2293 | 0.8219 | 1.0202 |
| PL | dbCAN_3:HMMER | 0.9210 | 0.2293 | 0.8219 | 1.0202 |
| PL | dbCAN_3:DIAMOND | 0.9329 | 0.1638 | 0.8620 | 1.0037 |
| PL | dbCAN_3:eCAMI | 0.7785 | 0.4198 | 0.5969 | 0.9601 |
| PL | dbCAN_4 | 0.9210 | 0.2293 | 0.8219 | 1.0202 |
| PL | dbCAN_4:HMMER | 0.9210 | 0.2293 | 0.8219 | 1.0202 |
| PL | dbCAN_4:DIAMOND | 0.9329 | 0.1638 | 0.8620 | 1.0037 |
| PL | dbCAN_4:dbCAN-sub | 0.9211 | 0.2293 | 0.8219 | 1.0202 |
| PL | CUPP | 0.7796 | 0.4203 | 0.5979 | 0.9614 |
| CE | dbCAN_2 | 0.6825 | 0.3922 | 0.4875 | 0.8775 |
| CE | dbCAN_2:HMMER | 0.6019 | 0.4201 | 0.3994 | 0.8044 |
| CE | dbCAN_2:DIAMOND | 0.7102 | 0.3901 | 0.5162 | 0.9042 |
| CE | dbCAN_2:Hotpep | 0.6974 | 0.3476 | 0.5186 | 0.8761 |
| CE | dbCAN_3 | 0.8006 | 0.3203 | 0.6359 | 0.9653 |
| CE | dbCAN_3:HMMER | 0.6909 | 0.3810 | 0.5014 | 0.8804 |
| CE | dbCAN_3:DIAMOND | 0.8037 | 0.3014 | 0.6487 | 0.9586 |
| CE | dbCAN_3:eCAMI | 0.7082 | 0.3722 | 0.5168 | 0.8995 |
| CE | dbCAN_4 | 0.7625 | 0.3416 | 0.5927 | 0.9324 |
| CE | dbCAN_4:HMMER | 0.7511 | 0.3412 | 0.5814 | 0.9208 |
| CE | dbCAN_4:DIAMOND | 0.8751 | 0.2163 | 0.7639 | 0.9863 |
| CE | dbCAN_4:dbCAN-sub | 0.7613 | 0.3408 | 0.5918 | 0.9307 |
| CE | CUPP | 0.6687 | 0.4313 | 0.4470 | 0.8905 |
| AA | dbCAN_2 | 0.7969 | 0.3372 | 0.6172 | 0.9765 |
| AA | dbCAN_2:HMMER | 0.8253 | 0.2793 | 0.6765 | 0.9741 |
| AA | dbCAN_2:DIAMOND | 0.8467 | 0.2585 | 0.7090 | 0.9845 |
| AA | dbCAN_2:Hotpep | 0.7208 | 0.3917 | 0.5121 | 0.9295 |
| AA | dbCAN_3 | 0.8501 | 0.2569 | 0.7132 | 0.9870 |
| AA | dbCAN_3:HMMER | 0.8322 | 0.2712 | 0.6877 | 0.9767 |
| AA | dbCAN_3:DIAMOND | 0.8557 | 0.1703 | 0.7650 | 0.9464 |
| AA | dbCAN_3:eCAMI | 0.6623 | 0.4141 | 0.4416 | 0.8829 |
| AA | dbCAN_4 | 0.8381 | 0.2675 | 0.6956 | 0.9806 |
| AA | dbCAN_4:HMMER | 0.8322 | 0.2712 | 0.6877 | 0.9767 |
| AA | dbCAN_4:DIAMOND | 0.8553 | 0.1790 | 0.7600 | 0.9507 |
| AA | dbCAN_4:dbCAN-sub | 0.8348 | 0.2690 | 0.6915 | 0.9781 |
| AA | CUPP | 0.6511 | 0.4322 | 0.4207 | 0.8814 |
| CBM | dbCAN_2 | 0.8126 | 0.3393 | 0.7208 | 0.9043 |
| CBM | dbCAN_2:HMMER | 0.7678 | 0.4055 | 0.6592 | 0.8764 |
| CBM | dbCAN_2:DIAMOND | 0.7979 | 0.3224 | 0.7108 | 0.8851 |
| CBM | dbCAN_2:Hotpep | 0.2788 | 0.3006 | 0.2066 | 0.3510 |
| CBM | dbCAN_3 | 0.8552 | 0.3137 | 0.7704 | 0.9400 |
| CBM | dbCAN_3:HMMER | 0.7857 | 0.3929 | 0.6805 | 0.8909 |
| CBM | dbCAN_3:DIAMOND | 0.8490 | 0.2977 | 0.7685 | 0.9295 |
| CBM | dbCAN_3:eCAMI | 0.4285 | 0.3532 | 0.3410 | 0.5160 |
| CBM | dbCAN_4 | 0.8451 | 0.3412 | 0.7537 | 0.9364 |
| CBM | dbCAN_4:HMMER | 0.8028 | 0.3786 | 0.7014 | 0.9042 |
| CBM | dbCAN_4:DIAMOND | 0.8676 | 0.2812 | 0.7916 | 0.9436 |
| CBM | dbCAN_4:dbCAN-sub | 0.8212 | 0.3608 | 0.7246 | 0.9179 |
| CBM | CUPP | 0.0000 | 0.0000 | 0.0000 | 0.0000 |
Figure 10.7: 95% confidence intervals of the precision of CAZy family classification across all CAZy families per CAZy class, for each CAZyme classifier.
Figure 10.8: Scatter plot of overlaying a one-dimensional box-and-whisker plot of precision for each CAZy family for each CAZyme classifier. Each CAZy family is represented as a single point on the plot.
| CAZy_class | Prediction_tool | Mean | Standard Deviation | Lower CI | Upper CI |
|---|---|---|---|---|---|
| GH | dbCAN_2 | 0.8881 | 0.2624 | 0.8436 | 0.9326 |
| GH | dbCAN_2:HMMER | 0.8554 | 0.3102 | 0.8036 | 0.9073 |
| GH | dbCAN_2:DIAMOND | 0.8853 | 0.2617 | 0.8409 | 0.9296 |
| GH | dbCAN_2:Hotpep | 0.8086 | 0.3148 | 0.7554 | 0.8618 |
| GH | dbCAN_3 | 0.9383 | 0.1932 | 0.9054 | 0.9712 |
| GH | dbCAN_3:HMMER | 0.8855 | 0.2747 | 0.8394 | 0.9315 |
| GH | dbCAN_3:DIAMOND | 0.9427 | 0.1908 | 0.9102 | 0.9752 |
| GH | dbCAN_3:eCAMI | 0.7603 | 0.3526 | 0.7007 | 0.8199 |
| GH | dbCAN_4 | 0.9200 | 0.2349 | 0.8804 | 0.9597 |
| GH | dbCAN_4:HMMER | 0.8927 | 0.2643 | 0.8483 | 0.9370 |
| GH | dbCAN_4:DIAMOND | 0.9485 | 0.1730 | 0.9190 | 0.9779 |
| GH | dbCAN_4:dbCAN-sub | 0.9079 | 0.2481 | 0.8661 | 0.9496 |
| GH | CUPP | 0.8005 | 0.3601 | 0.7392 | 0.8618 |
| GT | dbCAN_2 | 0.8656 | 0.2610 | 0.8055 | 0.9256 |
| GT | dbCAN_2:HMMER | 0.8287 | 0.2984 | 0.7605 | 0.8969 |
| GT | dbCAN_2:DIAMOND | 0.8742 | 0.2586 | 0.8147 | 0.9337 |
| GT | dbCAN_2:Hotpep | 0.8003 | 0.3072 | 0.7296 | 0.8710 |
| GT | dbCAN_3 | 0.9006 | 0.2230 | 0.8496 | 0.9515 |
| GT | dbCAN_3:HMMER | 0.8616 | 0.2504 | 0.8044 | 0.9188 |
| GT | dbCAN_3:DIAMOND | 0.9266 | 0.1899 | 0.8832 | 0.9700 |
| GT | dbCAN_3:eCAMI | 0.7985 | 0.3097 | 0.7277 | 0.8692 |
| GT | dbCAN_4 | 0.8923 | 0.2395 | 0.8376 | 0.9471 |
| GT | dbCAN_4:HMMER | 0.8503 | 0.2674 | 0.7897 | 0.9110 |
| GT | dbCAN_4:DIAMOND | 0.9263 | 0.1884 | 0.8832 | 0.9693 |
| GT | dbCAN_4:dbCAN-sub | 0.8915 | 0.2396 | 0.8368 | 0.9463 |
| GT | CUPP | 0.8230 | 0.2883 | 0.7567 | 0.8893 |
| PL | dbCAN_2 | 0.8319 | 0.3393 | 0.6852 | 0.9787 |
| PL | dbCAN_2:HMMER | 0.8337 | 0.3442 | 0.6848 | 0.9825 |
| PL | dbCAN_2:DIAMOND | 0.8484 | 0.3400 | 0.7014 | 0.9954 |
| PL | dbCAN_2:Hotpep | 0.7465 | 0.3610 | 0.5941 | 0.8990 |
| PL | dbCAN_3 | 0.9342 | 0.2161 | 0.8408 | 1.0276 |
| PL | dbCAN_3:HMMER | 0.9135 | 0.2222 | 0.8174 | 1.0096 |
| PL | dbCAN_3:DIAMOND | 0.9477 | 0.1308 | 0.8911 | 1.0043 |
| PL | dbCAN_3:eCAMI | 0.7043 | 0.3957 | 0.5332 | 0.8754 |
| PL | dbCAN_4 | 0.9135 | 0.2222 | 0.8174 | 1.0096 |
| PL | dbCAN_4:HMMER | 0.9135 | 0.2222 | 0.8174 | 1.0096 |
| PL | dbCAN_4:DIAMOND | 0.9489 | 0.1312 | 0.8922 | 1.0057 |
| PL | dbCAN_4:dbCAN-sub | 0.9139 | 0.2223 | 0.8177 | 1.0100 |
| PL | CUPP | 0.7307 | 0.4094 | 0.5537 | 0.9077 |
| CE | dbCAN_2 | 0.6948 | 0.3766 | 0.5075 | 0.8820 |
| CE | dbCAN_2:HMMER | 0.6399 | 0.4171 | 0.4388 | 0.8409 |
| CE | dbCAN_2:DIAMOND | 0.6906 | 0.3652 | 0.5090 | 0.8722 |
| CE | dbCAN_2:Hotpep | 0.6801 | 0.3221 | 0.5145 | 0.8458 |
| CE | dbCAN_3 | 0.8134 | 0.2992 | 0.6595 | 0.9672 |
| CE | dbCAN_3:HMMER | 0.7310 | 0.3672 | 0.5483 | 0.9136 |
| CE | dbCAN_3:DIAMOND | 0.8248 | 0.2636 | 0.6892 | 0.9603 |
| CE | dbCAN_3:eCAMI | 0.6668 | 0.3325 | 0.4959 | 0.8378 |
| CE | dbCAN_4 | 0.8015 | 0.3232 | 0.6408 | 0.9622 |
| CE | dbCAN_4:HMMER | 0.7905 | 0.3222 | 0.6303 | 0.9508 |
| CE | dbCAN_4:DIAMOND | 0.9041 | 0.1502 | 0.8269 | 0.9814 |
| CE | dbCAN_4:dbCAN-sub | 0.8015 | 0.3232 | 0.6408 | 0.9622 |
| CE | CUPP | 0.6880 | 0.4173 | 0.4734 | 0.9025 |
| AA | dbCAN_2 | 0.7720 | 0.3204 | 0.6012 | 0.9427 |
| AA | dbCAN_2:HMMER | 0.8344 | 0.2593 | 0.6963 | 0.9726 |
| AA | dbCAN_2:DIAMOND | 0.7937 | 0.2478 | 0.6617 | 0.9258 |
| AA | dbCAN_2:Hotpep | 0.7066 | 0.3711 | 0.5089 | 0.9043 |
| AA | dbCAN_3 | 0.8754 | 0.2438 | 0.7455 | 1.0053 |
| AA | dbCAN_3:HMMER | 0.8577 | 0.2494 | 0.7248 | 0.9906 |
| AA | dbCAN_3:DIAMOND | 0.8945 | 0.1283 | 0.8262 | 0.9629 |
| AA | dbCAN_3:eCAMI | 0.6465 | 0.3952 | 0.4359 | 0.8571 |
| AA | dbCAN_4 | 0.8626 | 0.2485 | 0.7302 | 0.9950 |
| AA | dbCAN_4:HMMER | 0.8577 | 0.2494 | 0.7248 | 0.9906 |
| AA | dbCAN_4:DIAMOND | 0.8972 | 0.1371 | 0.8242 | 0.9703 |
| AA | dbCAN_4:dbCAN-sub | 0.8600 | 0.2489 | 0.7273 | 0.9926 |
| AA | CUPP | 0.6685 | 0.4320 | 0.4383 | 0.8987 |
| CBM | dbCAN_2 | 0.7911 | 0.3255 | 0.7031 | 0.8791 |
| CBM | dbCAN_2:HMMER | 0.7000 | 0.4068 | 0.5911 | 0.8090 |
| CBM | dbCAN_2:DIAMOND | 0.7972 | 0.3121 | 0.7128 | 0.8816 |
| CBM | dbCAN_2:Hotpep | 0.3416 | 0.3155 | 0.2658 | 0.4174 |
| CBM | dbCAN_3 | 0.8334 | 0.3055 | 0.7508 | 0.9159 |
| CBM | dbCAN_3:HMMER | 0.7179 | 0.3973 | 0.6115 | 0.8243 |
| CBM | dbCAN_3:DIAMOND | 0.8551 | 0.2931 | 0.7758 | 0.9343 |
| CBM | dbCAN_3:eCAMI | 0.4658 | 0.3454 | 0.3803 | 0.5514 |
| CBM | dbCAN_4 | 0.8144 | 0.3410 | 0.7231 | 0.9057 |
| CBM | dbCAN_4:HMMER | 0.7349 | 0.3862 | 0.6314 | 0.8383 |
| CBM | dbCAN_4:DIAMOND | 0.8581 | 0.2917 | 0.7793 | 0.9370 |
| CBM | dbCAN_4:dbCAN-sub | 0.7832 | 0.3592 | 0.6870 | 0.8794 |
| CBM | CUPP | 0.0000 | 0.0000 | 0.0000 | 0.0000 |
Figure 10.9: 95% confidence intervals of the F1-score of CAZy family classification across all CAZy families per CAZy class, for each CAZyme classifier.
Figure 10.10: Scatter plot of overlaying a one-dimensional box-and-whisker plot of F1-score for each CAZy family for each CAZyme classifier. Each CAZy family is represented as a single point on the plot.
| CAZy_class | Prediction_tool | Mean | Standard Deviation | Lower CI | Upper CI |
|---|---|---|---|---|---|
| GH | dbCAN_2 | 0.9996 | 0.0013 | 0.9994 | 0.9998 |
| GH | dbCAN_2:HMMER | 0.9996 | 0.0014 | 0.9994 | 0.9998 |
| GH | dbCAN_2:DIAMOND | 0.9997 | 0.0008 | 0.9996 | 0.9998 |
| GH | dbCAN_2:Hotpep | 0.9994 | 0.0016 | 0.9991 | 0.9996 |
| GH | dbCAN_3 | 0.9998 | 0.0008 | 0.9996 | 0.9999 |
| GH | dbCAN_3:HMMER | 0.9996 | 0.0014 | 0.9994 | 0.9999 |
| GH | dbCAN_3:DIAMOND | 0.9998 | 0.0005 | 0.9997 | 0.9999 |
| GH | dbCAN_3:eCAMI | 0.9994 | 0.0012 | 0.9992 | 0.9996 |
| GH | dbCAN_4 | 0.9998 | 0.0013 | 0.9995 | 1.0000 |
| GH | dbCAN_4:HMMER | 0.9996 | 0.0014 | 0.9994 | 0.9999 |
| GH | dbCAN_4:DIAMOND | 0.9998 | 0.0005 | 0.9997 | 0.9999 |
| GH | dbCAN_4:dbCAN-sub | 0.9997 | 0.0013 | 0.9995 | 1.0000 |
| GH | CUPP | 0.9996 | 0.0013 | 0.9994 | 0.9998 |
| GT | dbCAN_2 | 0.9993 | 0.0017 | 0.9989 | 0.9997 |
| GT | dbCAN_2:HMMER | 0.9992 | 0.0021 | 0.9987 | 0.9997 |
| GT | dbCAN_2:DIAMOND | 0.9995 | 0.0011 | 0.9992 | 0.9997 |
| GT | dbCAN_2:Hotpep | 0.9986 | 0.0045 | 0.9976 | 0.9997 |
| GT | dbCAN_3 | 0.9996 | 0.0011 | 0.9993 | 0.9998 |
| GT | dbCAN_3:HMMER | 0.9992 | 0.0021 | 0.9987 | 0.9997 |
| GT | dbCAN_3:DIAMOND | 0.9997 | 0.0006 | 0.9996 | 0.9999 |
| GT | dbCAN_3:eCAMI | 0.9992 | 0.0018 | 0.9987 | 0.9996 |
| GT | dbCAN_4 | 0.9996 | 0.0013 | 0.9993 | 0.9999 |
| GT | dbCAN_4:HMMER | 0.9992 | 0.0021 | 0.9987 | 0.9997 |
| GT | dbCAN_4:DIAMOND | 0.9997 | 0.0007 | 0.9995 | 0.9999 |
| GT | dbCAN_4:dbCAN-sub | 0.9996 | 0.0013 | 0.9992 | 0.9999 |
| GT | CUPP | 0.9992 | 0.0018 | 0.9988 | 0.9996 |
| PL | dbCAN_2 | 0.9999 | 0.0003 | 0.9998 | 1.0000 |
| PL | dbCAN_2:HMMER | 0.9999 | 0.0002 | 0.9998 | 1.0000 |
| PL | dbCAN_2:DIAMOND | 0.9999 | 0.0002 | 0.9998 | 1.0000 |
| PL | dbCAN_2:Hotpep | 0.9998 | 0.0003 | 0.9997 | 0.9999 |
| PL | dbCAN_3 | 1.0000 | 0.0001 | 0.9999 | 1.0000 |
| PL | dbCAN_3:HMMER | 1.0000 | 0.0001 | 0.9999 | 1.0000 |
| PL | dbCAN_3:DIAMOND | 0.9999 | 0.0001 | 0.9999 | 1.0000 |
| PL | dbCAN_3:eCAMI | 0.9998 | 0.0003 | 0.9996 | 0.9999 |
| PL | dbCAN_4 | 1.0000 | 0.0001 | 0.9999 | 1.0000 |
| PL | dbCAN_4:HMMER | 1.0000 | 0.0001 | 0.9999 | 1.0000 |
| PL | dbCAN_4:DIAMOND | 1.0000 | 0.0001 | 0.9999 | 1.0000 |
| PL | dbCAN_4:dbCAN-sub | 1.0000 | 0.0001 | 0.9999 | 1.0000 |
| PL | CUPP | 0.9999 | 0.0003 | 0.9997 | 1.0000 |
| CE | dbCAN_2 | 0.9992 | 0.0014 | 0.9984 | 0.9999 |
| CE | dbCAN_2:HMMER | 0.9991 | 0.0013 | 0.9985 | 0.9998 |
| CE | dbCAN_2:DIAMOND | 0.9990 | 0.0014 | 0.9984 | 0.9997 |
| CE | dbCAN_2:Hotpep | 0.9987 | 0.0015 | 0.9980 | 0.9995 |
| CE | dbCAN_3 | 0.9991 | 0.0016 | 0.9983 | 0.9999 |
| CE | dbCAN_3:HMMER | 0.9991 | 0.0013 | 0.9985 | 0.9998 |
| CE | dbCAN_3:DIAMOND | 0.9992 | 0.0010 | 0.9987 | 0.9998 |
| CE | dbCAN_3:eCAMI | 0.9987 | 0.0015 | 0.9980 | 0.9995 |
| CE | dbCAN_4 | 0.9993 | 0.0012 | 0.9988 | 0.9999 |
| CE | dbCAN_4:HMMER | 0.9992 | 0.0013 | 0.9986 | 0.9999 |
| CE | dbCAN_4:DIAMOND | 0.9994 | 0.0009 | 0.9990 | 0.9999 |
| CE | dbCAN_4:dbCAN-sub | 0.9993 | 0.0012 | 0.9988 | 0.9999 |
| CE | CUPP | 0.9992 | 0.0012 | 0.9985 | 0.9998 |
| AA | dbCAN_2 | 0.9994 | 0.0010 | 0.9989 | 0.9999 |
| AA | dbCAN_2:HMMER | 0.9994 | 0.0011 | 0.9988 | 1.0000 |
| AA | dbCAN_2:DIAMOND | 0.9994 | 0.0009 | 0.9989 | 0.9998 |
| AA | dbCAN_2:Hotpep | 0.9993 | 0.0009 | 0.9988 | 0.9998 |
| AA | dbCAN_3 | 0.9996 | 0.0007 | 0.9992 | 1.0000 |
| AA | dbCAN_3:HMMER | 0.9996 | 0.0007 | 0.9992 | 0.9999 |
| AA | dbCAN_3:DIAMOND | 0.9995 | 0.0007 | 0.9992 | 0.9999 |
| AA | dbCAN_3:eCAMI | 0.9992 | 0.0010 | 0.9987 | 0.9997 |
| AA | dbCAN_4 | 0.9996 | 0.0007 | 0.9992 | 0.9999 |
| AA | dbCAN_4:HMMER | 0.9996 | 0.0007 | 0.9992 | 0.9999 |
| AA | dbCAN_4:DIAMOND | 0.9995 | 0.0006 | 0.9992 | 0.9999 |
| AA | dbCAN_4:dbCAN-sub | 0.9996 | 0.0007 | 0.9992 | 0.9999 |
| AA | CUPP | 0.9993 | 0.0009 | 0.9989 | 0.9998 |
| CBM | dbCAN_2 | 0.9993 | 0.0017 | 0.9988 | 0.9997 |
| CBM | dbCAN_2:HMMER | 0.9988 | 0.0031 | 0.9980 | 0.9996 |
| CBM | dbCAN_2:DIAMOND | 0.9994 | 0.0013 | 0.9991 | 0.9998 |
| CBM | dbCAN_2:Hotpep | 0.9970 | 0.0044 | 0.9960 | 0.9981 |
| CBM | dbCAN_3 | 0.9994 | 0.0013 | 0.9991 | 0.9998 |
| CBM | dbCAN_3:HMMER | 0.9988 | 0.0031 | 0.9980 | 0.9996 |
| CBM | dbCAN_3:DIAMOND | 0.9996 | 0.0010 | 0.9994 | 0.9999 |
| CBM | dbCAN_3:eCAMI | 0.9984 | 0.0023 | 0.9979 | 0.9990 |
| CBM | dbCAN_4 | 0.9995 | 0.0012 | 0.9992 | 0.9998 |
| CBM | dbCAN_4:HMMER | 0.9989 | 0.0030 | 0.9981 | 0.9997 |
| CBM | dbCAN_4:DIAMOND | 0.9997 | 0.0009 | 0.9994 | 0.9999 |
| CBM | dbCAN_4:dbCAN-sub | 0.9995 | 0.0011 | 0.9992 | 0.9998 |
| CBM | CUPP | 0.9978 | 0.0037 | 0.9968 | 0.9988 |
Figure 10.11: 95% confidence intervals of the accuarcy of CAZy family classification across all CAZy families per CAZy class, for each CAZyme classifier.
Figure 10.12: Scatter plot of overlaying a one-dimensional box-and-whisker plot of the accuracy for each CAZy family for each CAZyme classifier. Each CAZy family is represented as a single point on the plot.
For better resolution we can group the CAZy families by their parent CAzy classes, and compare the performances of the tools CAZy class, by CAZy class. Owing to the minimal variation in specificity scores, specificity was plotted as the percentage specificity log10.
Figure 10.13 shows the plotting of sensitivity against specificity for each Glycoside Hydrolase CAZy family.
Figure 10.13: Scatter plot of recall (sensitivity) against specificity for predicting each CAZy family for each CAZyme classifier in the CAZy class Glycoside Hydrolases. Each GH CAZy family is represented as a single point on the plot.
Figure 10.14 shows the plotting of sensitivity against specificity for each Glycosyltransferases CAZy family.
Figure 10.14: Scatter plot of recall (sensitivity) against specificity for predicting each CAZy family for each CAZyme classifier in the CAZy class Glycosyltransferases. Each GT CAZy family is represented as a single point on the plot.
Figure 10.13 shows the plotting of sensitivity against specificity for each Polysaccharide Lyases CAZy family.
Figure 10.15: Scatter plot of recall (sensitivity) against specificity for predicting each CAZy family for each CAZyme classifier in the CAZy class Polysaccharide Lyases. Each PL CAZy family is represented as a single point on the plot.
Figure 10.16 shows the plotting of sensitivity against specificity for each Carbohydrate Esterases CAZy family.
Figure 10.16: Scatter plot of recall (sensitivity) against specificity for predicting each CAZy family for each CAZyme classifier in the CAZy class Carbohydrate Esterases. Each CE CAZy family is represented as a single point on the plot.
Figure ?? shows the plotting of sensitivity against specificity for each Auxillary Activities CAZy family.
Figure 10.17: Scatter plot of recall (sensitivity) against specificity for predicting each CAZy family for each CAZyme classifier in the CAZy class Auxillary Activities. Each AA CAZy family is represented as a single point on the plot.
Figure 10.18 shows the plotting of sensitivity against specificity for each Carbohydrate Binding Module CAZy family.
Figure 10.18: Scatter plot of recall (sensitivity) against specificity for predicting each CAZy family for each CAZyme classifier in the CAZy class Carbohydrate Binding Modules. Each CBM CAZy family is represented as a single point on the plot.
We can pull out CAZy families for which at least three of the evaluated classifiers (when including the individual tools incoporated into dbCAN) produce a sensitivity score of less than 0.75 for said CAZy family.
CAZy annotates proteins in a domain-wise manner. Consequently, a single protein may be assigned to multiple CAZy families. The ability of a classifier to assign all the correct CAZy family annotations for a given protein when only evaluating the CAZy family classification performance per CAZy family, independently of all other CAZy classes.
Multilabel classification raises when a single instance can be assinged to multiple classes. In this evaluation a single instance is a protein and the classes are CAZy families, a single CAZyme can be assigned to multiple CAZy families. This is important to take into consideration because the same approaches for statistical evaluation of binary classification provided a limited view of the performance of the classifiers when applied to multilabel classification.
The CAZy family multi-label classification performance is represented by the Rand Index (RI) and Adjusted Rand Index (ARI). The RI is a quantitive measure of similarity between two clusterings by considering all pairs of samples and counting pairs that are assigned in the same or different clusters in the predicted and true clusterings. In this case the two clusters are the predicted and groud truth CAZy family annotations. The raw RI score is then “adjusted for chance” into the ARI score using the following scheme:
ARI = (RI - Expected_RI) / (max(RI) - Expected_RI)
This produces a score between 1 and -1. A score of 1 is produced if all predicted and known CAZy family annotations are identical, 0 if completely random clustering of -1 if systematically incorrect clustering and the number of incorrect classifications of proteins is greater than would be expected from randomly annotating proteins with CAZy families.
| Prediction_tool | Mean | Standard Deviation | Lower CI | Upper CI |
|---|---|---|---|---|
| dbCAN_2 | 0.9996 | 0.0013 | 0.9996 | 0.9997 |
| dbCAN_2:HMMER | 0.9995 | 0.0014 | 0.9995 | 0.9996 |
| dbCAN_2:DIAMOND | 0.9997 | 0.0012 | 0.9997 | 0.9997 |
| dbCAN_2:Hotpep | 0.9991 | 0.0023 | 0.9990 | 0.9991 |
| dbCAN_3 | 0.9998 | 0.0011 | 0.9997 | 0.9998 |
| dbCAN_3:HMMER | 0.9996 | 0.0014 | 0.9995 | 0.9996 |
| dbCAN_3:DIAMOND | 0.9998 | 0.0010 | 0.9998 | 0.9998 |
| dbCAN_3:eCAMI | 0.9994 | 0.0017 | 0.9994 | 0.9994 |
| dbCAN_4 | 0.9998 | 0.0011 | 0.9997 | 0.9998 |
| dbCAN_4:HMMER | 0.9996 | 0.0014 | 0.9996 | 0.9996 |
| dbCAN_4:DIAMOND | 0.9998 | 0.0009 | 0.9998 | 0.9998 |
| dbCAN_4:dbCAN-sub | 0.9998 | 0.0011 | 0.9997 | 0.9998 |
| CUPP | 0.9994 | 0.0015 | 0.9994 | 0.9995 |
| Prediction_tool | Mean | Standard Deviation | Lower CI | Upper CI |
|---|---|---|---|---|
| dbCAN_2 | 0.9259 | 0.2568 | 0.9219 | 0.9299 |
| dbCAN_2:HMMER | 0.9145 | 0.2702 | 0.9103 | 0.9187 |
| dbCAN_2:DIAMOND | 0.9386 | 0.2367 | 0.9349 | 0.9422 |
| dbCAN_2:Hotpep | 0.8635 | 0.3219 | 0.8585 | 0.8684 |
| dbCAN_3 | 0.9507 | 0.2127 | 0.9474 | 0.9540 |
| dbCAN_3:HMMER | 0.9201 | 0.2617 | 0.9161 | 0.9242 |
| dbCAN_3:DIAMOND | 0.9622 | 0.1878 | 0.9593 | 0.9651 |
| dbCAN_3:eCAMI | 0.8960 | 0.2928 | 0.8914 | 0.9005 |
| dbCAN_4 | 0.9538 | 0.2050 | 0.9507 | 0.9570 |
| dbCAN_4:HMMER | 0.9221 | 0.2598 | 0.9180 | 0.9261 |
| dbCAN_4:DIAMOND | 0.9636 | 0.1847 | 0.9608 | 0.9665 |
| dbCAN_4:dbCAN-sub | 0.9544 | 0.2032 | 0.9512 | 0.9575 |
| CUPP | 0.9012 | 0.2832 | 0.8968 | 0.9055 |
| Prediction_tool | Lower CI | Mean | Upper CI | Standard Deviation | Tax_group |
|---|---|---|---|---|---|
| dbCAN_2 | 0.9996 | 0.9996 | 0.9997 | 0.0013 | All |
| dbCAN_2:HMMER | 0.9995 | 0.9995 | 0.9996 | 0.0014 | All |
| dbCAN_2:DIAMOND | 0.9997 | 0.9997 | 0.9997 | 0.0012 | All |
| dbCAN_2:Hotpep | 0.9990 | 0.9991 | 0.9991 | 0.0023 | All |
| dbCAN_3 | 0.9997 | 0.9998 | 0.9998 | 0.0011 | All |
| dbCAN_3:HMMER | 0.9995 | 0.9996 | 0.9996 | 0.0014 | All |
| dbCAN_3:DIAMOND | 0.9998 | 0.9998 | 0.9998 | 0.0010 | All |
| dbCAN_3:eCAMI | 0.9994 | 0.9994 | 0.9994 | 0.0017 | All |
| dbCAN_4 | 0.9997 | 0.9998 | 0.9998 | 0.0011 | All |
| dbCAN_4:HMMER | 0.9996 | 0.9996 | 0.9996 | 0.0014 | All |
| dbCAN_4:DIAMOND | 0.9998 | 0.9998 | 0.9998 | 0.0009 | All |
| dbCAN_4:dbCAN-sub | 0.9997 | 0.9998 | 0.9998 | 0.0011 | All |
| CUPP | 0.9994 | 0.9994 | 0.9995 | 0.0015 | All |
| dbCAN_2 | 0.9996 | 0.9996 | 0.9997 | 0.0013 | Bacteria |
| dbCAN_2:HMMER | 0.9995 | 0.9996 | 0.9996 | 0.0014 | Bacteria |
| dbCAN_2:DIAMOND | 0.9997 | 0.9997 | 0.9997 | 0.0012 | Bacteria |
| dbCAN_2:Hotpep | 0.9989 | 0.9990 | 0.9990 | 0.0026 | Bacteria |
| dbCAN_3 | 0.9997 | 0.9997 | 0.9998 | 0.0011 | Bacteria |
| dbCAN_3:HMMER | 0.9995 | 0.9996 | 0.9996 | 0.0014 | Bacteria |
| dbCAN_3:DIAMOND | 0.9998 | 0.9998 | 0.9998 | 0.0010 | Bacteria |
| dbCAN_3:eCAMI | 0.9993 | 0.9994 | 0.9994 | 0.0019 | Bacteria |
| dbCAN_4 | 0.9998 | 0.9998 | 0.9998 | 0.0011 | Bacteria |
| dbCAN_4:HMMER | 0.9996 | 0.9996 | 0.9996 | 0.0013 | Bacteria |
| dbCAN_4:DIAMOND | 0.9998 | 0.9998 | 0.9998 | 0.0010 | Bacteria |
| dbCAN_4:dbCAN-sub | 0.9998 | 0.9998 | 0.9998 | 0.0011 | Bacteria |
| CUPP | 0.9994 | 0.9994 | 0.9995 | 0.0016 | Bacteria |
| dbCAN_2 | 0.9996 | 0.9996 | 0.9997 | 0.0013 | Eukaryote |
| dbCAN_2:HMMER | 0.9995 | 0.9995 | 0.9996 | 0.0014 | Eukaryote |
| dbCAN_2:DIAMOND | 0.9997 | 0.9997 | 0.9997 | 0.0011 | Eukaryote |
| dbCAN_2:Hotpep | 0.9992 | 0.9992 | 0.9993 | 0.0019 | Eukaryote |
| dbCAN_3 | 0.9997 | 0.9998 | 0.9998 | 0.0010 | Eukaryote |
| dbCAN_3:HMMER | 0.9995 | 0.9996 | 0.9996 | 0.0014 | Eukaryote |
| dbCAN_3:DIAMOND | 0.9998 | 0.9998 | 0.9999 | 0.0009 | Eukaryote |
| dbCAN_3:eCAMI | 0.9994 | 0.9994 | 0.9995 | 0.0015 | Eukaryote |
| dbCAN_4 | 0.9997 | 0.9997 | 0.9998 | 0.0011 | Eukaryote |
| dbCAN_4:HMMER | 0.9995 | 0.9996 | 0.9996 | 0.0014 | Eukaryote |
| dbCAN_4:DIAMOND | 0.9998 | 0.9999 | 0.9999 | 0.0008 | Eukaryote |
| dbCAN_4:dbCAN-sub | 0.9997 | 0.9997 | 0.9997 | 0.0011 | Eukaryote |
| CUPP | 0.9994 | 0.9995 | 0.9995 | 0.0014 | Eukaryote |
## X Genomic_accession Protein_accession Prediction_tool GH0 GH1 GH2 GH3 GH4
## 1 0 GCA_000023565.1 ACT05045.1 dbCAN_2:HMMER 0 0 0 0 0
## 2 1 GCA_000023565.1 ACT05046.1 dbCAN_2:HMMER 0 0 0 0 0
## 3 2 GCA_000023565.1 ACT05058.1 dbCAN_2:HMMER 0 0 0 0 0
## 4 3 GCA_000023565.1 ACT05060.1 dbCAN_2:HMMER 0 0 0 0 0
## 5 4 GCA_000023565.1 ACT05116.1 dbCAN_2:HMMER 0 0 0 0 0
## 6 5 GCA_000023565.1 ACT05119.1 dbCAN_2:HMMER 0 0 0 0 0
## 7 6 GCA_000023565.1 ACT05120.1 dbCAN_2:HMMER 0 0 0 0 0
## 8 7 GCA_000023565.1 ACT05125.1 dbCAN_2:HMMER 0 0 0 0 0
## 9 8 GCA_000023565.1 ACT05126.1 dbCAN_2:HMMER 0 0 0 0 0
## 10 9 GCA_000023565.1 ACT05145.1 dbCAN_2:HMMER 0 0 0 0 0
## 11 10 GCA_000023565.1 ACT05161.1 dbCAN_2:HMMER 0 0 0 0 0
## 12 11 GCA_000023565.1 ACT05162.1 dbCAN_2:HMMER 0 0 0 0 0
## 13 12 GCA_000023565.1 ACT05163.1 dbCAN_2:HMMER 0 0 0 0 0
## 14 13 GCA_000023565.1 ACT05168.1 dbCAN_2:HMMER 0 0 0 0 0
## 15 14 GCA_000023565.1 ACT05407.1 dbCAN_2:HMMER 0 0 0 0 0
## 16 15 GCA_000023565.1 ACT05492.1 dbCAN_2:HMMER 0 0 0 0 0
## 17 16 GCA_000023565.1 ACT05498.1 dbCAN_2:HMMER 0 0 0 0 0
## 18 17 GCA_000023565.1 ACT05526.1 dbCAN_2:HMMER 0 0 0 0 0
## 19 18 GCA_000023565.1 ACT05617.1 dbCAN_2:HMMER 0 1 0 0 0
## 20 19 GCA_000023565.1 ACT05628.1 dbCAN_2:HMMER 0 1 0 0 0
## 21 20 GCA_000023565.1 ACT05629.1 dbCAN_2:HMMER 0 1 0 0 0
## 22 21 GCA_000023565.1 ACT05699.1 dbCAN_2:HMMER 0 0 0 0 0
## 23 22 GCA_000023565.1 ACT05703.1 dbCAN_2:HMMER 0 0 0 0 0
## 24 23 GCA_000023565.1 ACT05879.1 dbCAN_2:HMMER 0 0 0 0 0
## 25 24 GCA_000023565.1 ACT05921.1 dbCAN_2:HMMER 0 0 0 0 0
## 26 25 GCA_000023565.1 ACT05953.1 dbCAN_2:HMMER 0 0 0 0 0
## 27 26 GCA_000023565.1 ACT05959.1 dbCAN_2:HMMER 0 0 0 0 0
## 28 27 GCA_000023565.1 ACT05960.1 dbCAN_2:HMMER 0 0 0 0 0
## 29 28 GCA_000023565.1 ACT05961.1 dbCAN_2:HMMER 0 0 0 0 0
## 30 29 GCA_000023565.1 ACT05962.1 dbCAN_2:HMMER 0 0 0 0 0
## 31 30 GCA_000023565.1 ACT05963.1 dbCAN_2:HMMER 0 0 0 0 0
## 32 31 GCA_000023565.1 ACT06136.1 dbCAN_2:HMMER 0 0 0 0 0
## 33 32 GCA_000023565.1 ACT06142.1 dbCAN_2:HMMER 0 0 0 0 0
## 34 33 GCA_000023565.1 ACT06143.1 dbCAN_2:HMMER 0 0 0 0 0
## 35 34 GCA_000023565.1 ACT06296.1 dbCAN_2:HMMER 0 0 0 0 0
## 36 35 GCA_000023565.1 ACT06297.1 dbCAN_2:HMMER 0 0 0 0 0
## 37 36 GCA_000023565.1 ACT06318.1 dbCAN_2:HMMER 0 0 0 0 0
## 38 37 GCA_000023565.1 ACT06347.1 dbCAN_2:HMMER 0 0 0 0 0
## 39 38 GCA_000023565.1 ACT06381.1 dbCAN_2:HMMER 0 0 0 0 0
## 40 39 GCA_000023565.1 ACT06383.1 dbCAN_2:HMMER 0 0 0 0 0
## 41 40 GCA_000023565.1 ACT06384.1 dbCAN_2:HMMER 0 0 0 0 0
## 42 41 GCA_000023565.1 ACT06415.1 dbCAN_2:HMMER 0 0 0 0 0
## 43 42 GCA_000023565.1 ACT06436.1 dbCAN_2:HMMER 0 0 0 0 0
## 44 43 GCA_000023565.1 ACT06459.1 dbCAN_2:HMMER 0 0 0 0 0
## 45 44 GCA_000023565.1 ACT06490.1 dbCAN_2:HMMER 0 0 0 1 0
## 46 45 GCA_000023565.1 ACT06558.1 dbCAN_2:HMMER 0 1 0 0 0
## 47 46 GCA_000023565.1 ACT06752.1 dbCAN_2:HMMER 0 0 0 0 0
## 48 47 GCA_000023565.1 ACT06797.1 dbCAN_2:HMMER 0 0 0 0 0
## 49 48 GCA_000023565.1 ACT06819.1 dbCAN_2:HMMER 0 0 0 0 0
## 50 49 GCA_000023565.1 ACT06866.1 dbCAN_2:HMMER 0 0 0 0 0
## 51 50 GCA_000023565.1 ACT06959.1 dbCAN_2:HMMER 0 0 0 0 0
## 52 51 GCA_000023565.1 ACT06972.1 dbCAN_2:HMMER 0 0 0 0 0
## 53 52 GCA_000023565.1 ACT06995.1 dbCAN_2:HMMER 0 0 0 0 0
## 54 53 GCA_000023565.1 ACT07147.1 dbCAN_2:HMMER 0 0 0 0 0
## 55 54 GCA_000023565.1 ACT07309.1 dbCAN_2:HMMER 0 0 0 0 0
## 56 55 GCA_000023565.1 ACT07337.1 dbCAN_2:HMMER 0 0 0 1 0
## 57 56 GCA_000023565.1 ACT07381.1 dbCAN_2:HMMER 0 0 0 1 0
## 58 57 GCA_000023565.1 ACT07390.1 dbCAN_2:HMMER 0 0 0 0 0
## 59 58 GCA_000023565.1 ACT07487.1 dbCAN_2:HMMER 0 0 0 0 0
## 60 59 GCA_000023565.1 ACT07558.1 dbCAN_2:HMMER 0 0 1 0 0
## 61 60 GCA_000023565.1 ACT07677.1 dbCAN_2:HMMER 0 0 0 0 0
## 62 61 GCA_000023565.1 ACT07684.1 dbCAN_2:HMMER 0 0 0 0 0
## 63 62 GCA_000023565.1 ACT07686.1 dbCAN_2:HMMER 0 0 0 0 0
## 64 63 GCA_000023565.1 ACT07765.1 dbCAN_2:HMMER 0 0 0 0 0
## 65 64 GCA_000023565.1 ACT07852.1 dbCAN_2:HMMER 0 0 0 0 0
## 66 65 GCA_000023565.1 ACT07974.1 dbCAN_2:HMMER 0 0 0 0 0
## 67 66 GCA_000023565.1 ACT08009.1 dbCAN_2:HMMER 0 0 0 0 0
## 68 67 GCA_000023565.1 ACT08030.1 dbCAN_2:HMMER 0 0 0 0 0
## 69 68 GCA_000023565.1 ACT08051.1 dbCAN_2:HMMER 0 0 0 0 0
## 70 69 GCA_000023565.1 ACT08102.1 dbCAN_2:HMMER 0 0 0 0 0
## 71 70 GCA_000023565.1 ACT08124.1 dbCAN_2:HMMER 0 0 0 0 0
## 72 71 GCA_000023565.1 ACT08148.1 dbCAN_2:HMMER 0 0 0 0 0
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## 143 0 0 0 0 0 0 0 0 0 0 0 0
## 144 0 0 0 0 0 0 0 0 0 0 0 0
## 145 0 0 0 0 0 0 0 0 0 0 0 0
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## 147 0 0 0 0 0 0 0 0 0 0 0 0
## 148 0 0 0 0 0 0 0 0 0 0 0 0
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## 150 0 0 0 0 0 0 0 0 0 0 0 0
## 151 0 0 0 0 0 0 0 0 0 0 0 0
## 152 0 0 0 0 0 0 0 0 0 0 0 0
## 153 0 0 0 0 0 0 0 0 0 0 0 0
## 154 0 0 0 0 0 0 0 0 0 0 0 0
## 155 0 0 0 0 0 0 0 0 0 0 0 0
## 156 0 0 0 0 0 0 0 0 0 0 0 0
## 157 0 0 0 0 0 0 0 0 0 0 0 0
## 158 0 0 0 0 0 0 0 0 0 0 0 0
## 159 0 0 0 0 0 0 0 0 0 0 0 0
## 160 0 0 0 0 0 0 0 0 0 0 0 0
## 161 0 0 0 0 0 0 0 0 0 0 0 0
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## 163 0 0 0 0 0 0 0 0 0 0 0 0
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## 165 0 0 0 0 0 0 0 0 0 0 0 0
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## 168 0 0 0 0 0 0 0 0 0 0 0 0
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## 170 0 0 0 0 0 0 0 0 0 0 0 0
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## 174 0 0 0 0 0 0 0 0 0 0 0 0
## 175 0 0 0 0 0 0 0 0 0 0 0 0
## 176 0 0 0 0 0 0 0 0 0 0 0 0
## 177 0 0 0 0 0 0 0 0 0 0 0 0
## 178 0 0 0 0 0 0 0 0 0 0 0 0
## 179 0 0 0 0 0 0 0 0 0 0 0 0
## 180 0 0 0 0 0 0 0 0 0 0 0 0
## 181 0 0 0 0 0 0 0 0 0 0 0 0
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## 183 0 0 0 0 0 0 0 0 0 0 0 0
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## 185 0 0 0 0 0 0 0 0 0 0 0 0
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## 188 0 0 0 0 0 0 0 0 0 0 0 0
## 189 0 0 0 0 0 0 0 0 0 0 0 0
## 190 0 0 0 0 0 0 0 0 0 0 0 0
## 191 0 0 0 0 0 0 0 0 0 0 0 0
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## 201 0 0 0 0 0 0 0 0 0 0 0 0
## 202 0 0 0 0 0 0 0 0 0 0 0 0
## 203 0 0 0 0 0 0 0 0 0 0 0 0
## CBM81 CBM82 CBM83 CBM84 CBM85 CBM86 CBM87 CBM88 CBM89 CBM90 CBM91 CBM92
## 1 0 0 0 0 0 0 0 0 0 0 0 0
## 2 0 0 0 0 0 0 0 0 0 0 0 0
## 3 0 0 0 0 0 0 0 0 0 0 0 0
## 4 0 0 0 0 0 0 0 0 0 0 0 0
## 5 0 0 0 0 0 0 0 0 0 0 0 0
## 6 0 0 0 0 0 0 0 0 0 0 0 0
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## 143 0 0 0 0 0 0 0 0 0 0 0 0
## 144 0 0 0 0 0 0 0 0 0 0 0 0
## 145 0 0 0 0 0 0 0 0 0 0 0 0
## 146 0 0 0 0 0 0 0 0 0 0 0 0
## 147 0 0 0 0 0 0 0 0 0 0 0 0
## 148 0 0 0 0 0 0 0 0 0 0 0 0
## 149 0 0 0 0 0 0 0 0 0 0 0 0
## 150 0 0 0 0 0 0 0 0 0 0 0 0
## 151 0 0 0 0 0 0 0 0 0 0 0 0
## 152 0 0 0 0 0 0 0 0 0 0 0 0
## 153 0 0 0 0 0 0 0 0 0 0 0 0
## 154 0 0 0 0 0 0 0 0 0 0 0 0
## 155 0 0 0 0 0 0 0 0 0 0 0 0
## 156 0 0 0 0 0 0 0 0 0 0 0 0
## 157 0 0 0 0 0 0 0 0 0 0 0 0
## 158 0 0 0 0 0 0 0 0 0 0 0 0
## 159 0 0 0 0 0 0 0 0 0 0 0 0
## 160 0 0 0 0 0 0 0 0 0 0 0 0
## 161 0 0 0 0 0 0 0 0 0 0 0 0
## 162 0 0 0 0 0 0 0 0 0 0 0 0
## 163 0 0 0 0 0 0 0 0 0 0 0 0
## 164 0 0 0 0 0 0 0 0 0 0 0 0
## 165 0 0 0 0 0 0 0 0 0 0 0 0
## 166 0 0 0 0 0 0 0 0 0 0 0 0
## 167 0 0 0 0 0 0 0 0 0 0 0 0
## 168 0 0 0 0 0 0 0 0 0 0 0 0
## 169 0 0 0 0 0 0 0 0 0 0 0 0
## 170 0 0 0 0 0 0 0 0 0 0 0 0
## 171 0 0 0 0 0 0 0 0 0 0 0 0
## 172 0 0 0 0 0 0 0 0 0 0 0 0
## 173 0 0 0 0 0 0 0 0 0 0 0 0
## 174 0 0 0 0 0 0 0 0 0 0 0 0
## 175 0 0 0 0 0 0 0 0 0 0 0 0
## 176 0 0 0 0 0 0 0 0 0 0 0 0
## 177 0 0 0 0 0 0 0 0 0 0 0 0
## 178 0 0 0 0 0 0 0 0 0 0 0 0
## 179 0 0 0 0 0 0 0 0 0 0 0 0
## 180 0 0 0 0 0 0 0 0 0 0 0 0
## 181 0 0 0 0 0 0 0 0 0 0 0 0
## 182 0 0 0 0 0 0 0 0 0 0 0 0
## 183 0 0 0 0 0 0 0 0 0 0 0 0
## 184 0 0 0 0 0 0 0 0 0 0 0 0
## 185 0 0 0 0 0 0 0 0 0 0 0 0
## 186 0 0 0 0 0 0 0 0 0 0 0 0
## 187 0 0 0 0 0 0 0 0 0 0 0 0
## 188 0 0 0 0 0 0 0 0 0 0 0 0
## 189 0 0 0 0 0 0 0 0 0 0 0 0
## 190 0 0 0 0 0 0 0 0 0 0 0 0
## 191 0 0 0 0 0 0 0 0 0 0 0 0
## 192 0 0 0 0 0 0 0 0 0 0 0 0
## 193 0 0 0 0 0 0 0 0 0 0 0 0
## 194 0 0 0 0 0 0 0 0 0 0 0 0
## 195 0 0 0 0 0 0 0 0 0 0 0 0
## 196 0 0 0 0 0 0 0 0 0 0 0 0
## 197 0 0 0 0 0 0 0 0 0 0 0 0
## 198 0 0 0 0 0 0 0 0 0 0 0 0
## 199 0 0 0 0 0 0 0 0 0 0 0 0
## 200 0 0 0 0 0 0 0 0 0 0 0 0
## 201 0 0 0 0 0 0 0 0 0 0 0 0
## 202 0 0 0 0 0 0 0 0 0 0 0 0
## 203 0 0 0 0 0 0 0 0 0 0 0 0
## CBM93 CBM94 CBM95 CBM96 CBM97 Rand_index_freq Adjusted_Rand_index_freq
## 1 0 0 0 0 0 1.0000000 1.0000000
## 2 0 0 0 0 0 1.0000000 1.0000000
## 3 0 0 0 0 0 1.0000000 1.0000000
## 4 0 0 0 0 0 1.0000000 1.0000000
## 5 0 0 0 0 0 1.0000000 1.0000000
## 6 0 0 0 0 0 1.0000000 1.0000000
## 7 0 0 0 0 0 1.0000000 1.0000000
## 8 0 0 0 0 0 1.0000000 1.0000000
## 9 0 0 0 0 0 1.0000000 1.0000000
## 10 0 0 0 0 0 1.0000000 1.0000000
## 11 0 0 0 0 0 1.0000000 1.0000000
## 12 0 0 0 0 0 1.0000000 1.0000000
## 13 0 0 0 0 0 1.0000000 1.0000000
## 14 0 0 0 0 0 1.0000000 1.0000000
## 15 0 0 0 0 0 1.0000000 1.0000000
## 16 0 0 0 0 0 1.0000000 1.0000000
## 17 0 0 0 0 0 1.0000000 1.0000000
## 18 0 0 0 0 0 1.0000000 1.0000000
## 19 0 0 0 0 0 1.0000000 1.0000000
## 20 0 0 0 0 0 1.0000000 1.0000000
## 21 0 0 0 0 0 1.0000000 1.0000000
## 22 0 0 0 0 0 1.0000000 1.0000000
## 23 0 0 0 0 0 1.0000000 1.0000000
## 24 0 0 0 0 0 0.9958506 0.6643483
## 25 0 0 0 0 0 0.9958506 0.6643483
## 26 0 0 0 0 0 1.0000000 1.0000000
## 27 0 0 0 0 0 1.0000000 1.0000000
## 28 0 0 0 0 0 1.0000000 1.0000000
## 29 0 0 0 0 0 1.0000000 1.0000000
## 30 0 0 0 0 0 1.0000000 1.0000000
## 31 0 0 0 0 0 1.0000000 1.0000000
## 32 0 0 0 0 0 1.0000000 1.0000000
## 33 0 0 0 0 0 1.0000000 1.0000000
## 34 0 0 0 0 0 1.0000000 1.0000000
## 35 0 0 0 0 0 1.0000000 1.0000000
## 36 0 0 0 0 0 0.9958506 0.6643483
## 37 0 0 0 0 0 1.0000000 1.0000000
## 38 0 0 0 0 0 1.0000000 1.0000000
## 39 0 0 0 0 0 1.0000000 1.0000000
## 40 0 0 0 0 0 1.0000000 1.0000000
## 41 0 0 0 0 0 0.9958506 0.6643483
## 42 0 0 0 0 0 1.0000000 1.0000000
## 43 0 0 0 0 0 1.0000000 1.0000000
## 44 0 0 0 0 0 1.0000000 1.0000000
## 45 0 0 0 0 0 1.0000000 1.0000000
## 46 0 0 0 0 0 1.0000000 1.0000000
## 47 0 0 0 0 0 1.0000000 1.0000000
## 48 0 0 0 0 0 1.0000000 1.0000000
## 49 0 0 0 0 0 1.0000000 1.0000000
## 50 0 0 0 0 0 1.0000000 1.0000000
## 51 0 0 0 0 0 1.0000000 1.0000000
## 52 0 0 0 0 0 1.0000000 1.0000000
## 53 0 0 0 0 0 1.0000000 1.0000000
## 54 0 0 0 0 0 1.0000000 1.0000000
## 55 0 0 0 0 0 1.0000000 1.0000000
## 56 0 0 0 0 0 1.0000000 1.0000000
## 57 0 0 0 0 0 1.0000000 1.0000000
## 58 0 0 0 0 0 1.0000000 1.0000000
## 59 0 0 0 0 0 1.0000000 1.0000000
## 60 0 0 0 0 0 1.0000000 1.0000000
## 61 0 0 0 0 0 1.0000000 1.0000000
## 62 0 0 0 0 0 1.0000000 1.0000000
## 63 0 0 0 0 0 1.0000000 1.0000000
## 64 0 0 0 0 0 1.0000000 1.0000000
## 65 0 0 0 0 0 1.0000000 1.0000000
## 66 0 0 0 0 0 1.0000000 1.0000000
## 67 0 0 0 0 0 1.0000000 1.0000000
## 68 0 0 0 0 0 1.0000000 1.0000000
## 69 0 0 0 0 0 1.0000000 1.0000000
## 70 0 0 0 0 0 1.0000000 1.0000000
## 71 0 0 0 0 0 1.0000000 1.0000000
## 72 0 0 0 0 0 1.0000000 1.0000000
## 73 0 0 0 0 0 0.9958506 0.6643483
## 74 0 0 0 0 0 1.0000000 1.0000000
## 75 0 0 0 0 0 1.0000000 1.0000000
## 76 0 0 0 0 0 1.0000000 1.0000000
## 77 0 0 0 0 0 1.0000000 1.0000000
## 78 0 0 0 0 0 1.0000000 1.0000000
## 79 0 0 0 0 0 1.0000000 1.0000000
## 80 0 0 0 0 0 1.0000000 1.0000000
## 81 0 0 0 0 0 1.0000000 1.0000000
## 82 0 0 0 0 0 1.0000000 1.0000000
## 83 0 0 0 0 0 1.0000000 1.0000000
## 84 0 0 0 0 0 1.0000000 1.0000000
## 85 0 0 0 0 0 1.0000000 1.0000000
## 86 0 0 0 0 0 1.0000000 1.0000000
## 87 0 0 0 0 0 1.0000000 1.0000000
## 88 0 0 0 0 0 1.0000000 1.0000000
## 89 0 0 0 0 0 1.0000000 1.0000000
## 90 0 0 0 0 0 1.0000000 1.0000000
## 91 0 0 0 0 0 1.0000000 1.0000000
## 92 0 0 0 0 0 1.0000000 1.0000000
## 93 0 0 0 0 0 1.0000000 1.0000000
## 94 0 0 0 0 0 0.9958506 0.0000000
## 95 0 0 0 0 0 0.9958506 0.0000000
## 96 0 0 0 0 0 0.9958506 0.0000000
## 97 0 0 0 0 0 1.0000000 1.0000000
## 98 0 0 0 0 0 0.9958506 0.0000000
## 99 0 0 0 0 0 0.9958506 0.0000000
## 100 0 0 0 0 0 0.9958506 0.0000000
## 101 0 0 0 0 0 1.0000000 1.0000000
## 102 0 0 0 0 0 1.0000000 1.0000000
## 103 0 0 0 0 0 1.0000000 1.0000000
## 104 0 0 0 0 0 1.0000000 1.0000000
## 105 0 0 0 0 0 1.0000000 1.0000000
## 106 0 0 0 0 0 1.0000000 1.0000000
## 107 0 0 0 0 0 1.0000000 1.0000000
## 108 0 0 0 0 0 1.0000000 1.0000000
## 109 0 0 0 0 0 1.0000000 1.0000000
## 110 0 0 0 0 0 1.0000000 1.0000000
## 111 0 0 0 0 0 1.0000000 1.0000000
## 112 0 0 0 0 0 1.0000000 1.0000000
## 113 0 0 0 0 0 1.0000000 1.0000000
## 114 0 0 0 0 0 1.0000000 1.0000000
## 115 0 0 0 0 0 1.0000000 1.0000000
## 116 0 0 0 0 0 1.0000000 1.0000000
## 117 0 0 0 0 0 1.0000000 1.0000000
## 118 0 0 0 0 0 1.0000000 1.0000000
## 119 0 0 0 0 0 1.0000000 1.0000000
## 120 0 0 0 0 0 1.0000000 1.0000000
## 121 0 0 0 0 0 1.0000000 1.0000000
## 122 0 0 0 0 0 1.0000000 1.0000000
## 123 0 0 0 0 0 1.0000000 1.0000000
## 124 0 0 0 0 0 1.0000000 1.0000000
## 125 0 0 0 0 0 1.0000000 1.0000000
## 126 0 0 0 0 0 1.0000000 1.0000000
## 127 0 0 0 0 0 1.0000000 1.0000000
## 128 0 0 0 0 0 1.0000000 1.0000000
## 129 0 0 0 0 0 1.0000000 1.0000000
## 130 0 0 0 0 0 1.0000000 1.0000000
## 131 0 0 0 0 0 1.0000000 1.0000000
## 132 0 0 0 0 0 1.0000000 1.0000000
## 133 0 0 0 0 0 1.0000000 1.0000000
## 134 0 0 0 0 0 1.0000000 1.0000000
## 135 0 0 0 0 0 1.0000000 1.0000000
## 136 0 0 0 0 0 1.0000000 1.0000000
## 137 0 0 0 0 0 0.9958506 0.0000000
## 138 0 0 0 0 0 1.0000000 1.0000000
## 139 0 0 0 0 0 1.0000000 1.0000000
## 140 0 0 0 0 0 1.0000000 1.0000000
## 141 0 0 0 0 0 1.0000000 1.0000000
## 142 0 0 0 0 0 1.0000000 1.0000000
## 143 0 0 0 0 0 1.0000000 1.0000000
## 144 0 0 0 0 0 1.0000000 1.0000000
## 145 0 0 0 0 0 1.0000000 1.0000000
## 146 0 0 0 0 0 1.0000000 1.0000000
## 147 0 0 0 0 0 1.0000000 1.0000000
## 148 0 0 0 0 0 1.0000000 1.0000000
## 149 0 0 0 0 0 1.0000000 1.0000000
## 150 0 0 0 0 0 1.0000000 1.0000000
## 151 0 0 0 0 0 1.0000000 1.0000000
## 152 0 0 0 0 0 1.0000000 1.0000000
## 153 0 0 0 0 0 1.0000000 1.0000000
## 154 0 0 0 0 0 1.0000000 1.0000000
## 155 0 0 0 0 0 1.0000000 1.0000000
## 156 0 0 0 0 0 1.0000000 1.0000000
## 157 0 0 0 0 0 1.0000000 1.0000000
## 158 0 0 0 0 0 1.0000000 1.0000000
## 159 0 0 0 0 0 1.0000000 1.0000000
## 160 0 0 0 0 0 1.0000000 1.0000000
## 161 0 0 0 0 0 1.0000000 1.0000000
## 162 0 0 0 0 0 1.0000000 1.0000000
## 163 0 0 0 0 0 1.0000000 1.0000000
## 164 0 0 0 0 0 1.0000000 1.0000000
## 165 0 0 0 0 0 1.0000000 1.0000000
## 166 0 0 0 0 0 1.0000000 1.0000000
## 167 0 0 0 0 0 1.0000000 1.0000000
## 168 0 0 0 0 0 1.0000000 1.0000000
## 169 0 0 0 0 0 1.0000000 1.0000000
## 170 0 0 0 0 0 1.0000000 1.0000000
## 171 0 0 0 0 0 1.0000000 1.0000000
## 172 0 0 0 0 0 1.0000000 1.0000000
## 173 0 0 0 0 0 1.0000000 1.0000000
## 174 0 0 0 0 0 1.0000000 1.0000000
## 175 0 0 0 0 0 1.0000000 1.0000000
## 176 0 0 0 0 0 1.0000000 1.0000000
## 177 0 0 0 0 0 1.0000000 1.0000000
## 178 0 0 0 0 0 1.0000000 1.0000000
## 179 0 0 0 0 0 1.0000000 1.0000000
## 180 0 0 0 0 0 1.0000000 1.0000000
## 181 0 0 0 0 0 1.0000000 1.0000000
## 182 0 0 0 0 0 1.0000000 1.0000000
## 183 0 0 0 0 0 1.0000000 1.0000000
## 184 0 0 0 0 0 1.0000000 1.0000000
## 185 0 0 0 0 0 1.0000000 1.0000000
## 186 0 0 0 0 0 1.0000000 1.0000000
## 187 0 0 0 0 0 1.0000000 1.0000000
## 188 0 0 0 0 0 1.0000000 1.0000000
## 189 0 0 0 0 0 1.0000000 1.0000000
## 190 0 0 0 0 0 1.0000000 1.0000000
## 191 0 0 0 0 0 1.0000000 1.0000000
## 192 0 0 0 0 0 1.0000000 1.0000000
## 193 0 0 0 0 0 1.0000000 1.0000000
## 194 0 0 0 0 0 1.0000000 1.0000000
## 195 0 0 0 0 0 1.0000000 1.0000000
## 196 0 0 0 0 0 1.0000000 1.0000000
## 197 0 0 0 0 0 1.0000000 1.0000000
## 198 0 0 0 0 0 1.0000000 1.0000000
## 199 0 0 0 0 0 1.0000000 1.0000000
## 200 0 0 0 0 0 1.0000000 1.0000000
## 201 0 0 0 0 0 1.0000000 1.0000000
## 202 0 0 0 0 0 1.0000000 1.0000000
## 203 0 0 0 0 0 1.0000000 1.0000000
## Rand_index_binary Adjusted_Rand_index_binary Tax_group
## 1 1.0000000 1.0000000 Bacteria
## 2 1.0000000 1.0000000 Bacteria
## 3 1.0000000 1.0000000 Bacteria
## 4 1.0000000 1.0000000 Bacteria
## 5 1.0000000 1.0000000 Bacteria
## 6 1.0000000 1.0000000 Bacteria
## 7 1.0000000 1.0000000 Bacteria
## 8 1.0000000 1.0000000 Bacteria
## 9 1.0000000 1.0000000 Bacteria
## 10 1.0000000 1.0000000 Bacteria
## 11 1.0000000 1.0000000 Bacteria
## 12 1.0000000 1.0000000 Bacteria
## 13 1.0000000 1.0000000 Bacteria
## 14 1.0000000 1.0000000 Bacteria
## 15 1.0000000 1.0000000 Bacteria
## 16 1.0000000 1.0000000 Bacteria
## 17 1.0000000 1.0000000 Bacteria
## 18 1.0000000 1.0000000 Bacteria
## 19 1.0000000 1.0000000 Bacteria
## 20 1.0000000 1.0000000 Bacteria
## 21 1.0000000 1.0000000 Bacteria
## 22 1.0000000 1.0000000 Bacteria
## 23 1.0000000 1.0000000 Bacteria
## 24 0.9958506 0.6643483 Bacteria
## 25 0.9958506 0.6643483 Bacteria
## 26 1.0000000 1.0000000 Bacteria
## 27 1.0000000 1.0000000 Bacteria
## 28 1.0000000 1.0000000 Bacteria
## 29 1.0000000 1.0000000 Bacteria
## 30 1.0000000 1.0000000 Bacteria
## 31 1.0000000 1.0000000 Bacteria
## 32 1.0000000 1.0000000 Bacteria
## 33 1.0000000 1.0000000 Bacteria
## 34 1.0000000 1.0000000 Bacteria
## 35 1.0000000 1.0000000 Bacteria
## 36 0.9958506 0.6643483 Bacteria
## 37 1.0000000 1.0000000 Bacteria
## 38 1.0000000 1.0000000 Bacteria
## 39 1.0000000 1.0000000 Bacteria
## 40 1.0000000 1.0000000 Bacteria
## 41 0.9958506 0.6643483 Bacteria
## 42 1.0000000 1.0000000 Bacteria
## 43 1.0000000 1.0000000 Bacteria
## 44 1.0000000 1.0000000 Bacteria
## 45 1.0000000 1.0000000 Bacteria
## 46 1.0000000 1.0000000 Bacteria
## 47 1.0000000 1.0000000 Bacteria
## 48 1.0000000 1.0000000 Bacteria
## 49 1.0000000 1.0000000 Bacteria
## 50 1.0000000 1.0000000 Bacteria
## 51 1.0000000 1.0000000 Bacteria
## 52 1.0000000 1.0000000 Bacteria
## 53 1.0000000 1.0000000 Bacteria
## 54 1.0000000 1.0000000 Bacteria
## 55 1.0000000 1.0000000 Bacteria
## 56 1.0000000 1.0000000 Bacteria
## 57 1.0000000 1.0000000 Bacteria
## 58 1.0000000 1.0000000 Bacteria
## 59 1.0000000 1.0000000 Bacteria
## 60 1.0000000 1.0000000 Bacteria
## 61 1.0000000 1.0000000 Bacteria
## 62 1.0000000 1.0000000 Bacteria
## 63 1.0000000 1.0000000 Bacteria
## 64 1.0000000 1.0000000 Bacteria
## 65 1.0000000 1.0000000 Bacteria
## 66 1.0000000 1.0000000 Bacteria
## 67 1.0000000 1.0000000 Bacteria
## 68 1.0000000 1.0000000 Bacteria
## 69 1.0000000 1.0000000 Bacteria
## 70 1.0000000 1.0000000 Bacteria
## 71 1.0000000 1.0000000 Bacteria
## 72 1.0000000 1.0000000 Bacteria
## 73 0.9958506 0.6643483 Bacteria
## 74 1.0000000 1.0000000 Bacteria
## 75 1.0000000 1.0000000 Bacteria
## 76 1.0000000 1.0000000 Bacteria
## 77 1.0000000 1.0000000 Bacteria
## 78 1.0000000 1.0000000 Bacteria
## 79 1.0000000 1.0000000 Bacteria
## 80 1.0000000 1.0000000 Bacteria
## 81 1.0000000 1.0000000 Bacteria
## 82 1.0000000 1.0000000 Bacteria
## 83 1.0000000 1.0000000 Bacteria
## 84 1.0000000 1.0000000 Bacteria
## 85 1.0000000 1.0000000 Bacteria
## 86 1.0000000 1.0000000 Bacteria
## 87 1.0000000 1.0000000 Bacteria
## 88 1.0000000 1.0000000 Bacteria
## 89 1.0000000 1.0000000 Bacteria
## 90 1.0000000 1.0000000 Bacteria
## 91 1.0000000 1.0000000 Bacteria
## 92 1.0000000 1.0000000 Bacteria
## 93 1.0000000 1.0000000 Bacteria
## 94 0.9958506 0.0000000 Bacteria
## 95 0.9958506 0.0000000 Bacteria
## 96 0.9958506 0.0000000 Bacteria
## 97 1.0000000 1.0000000 Bacteria
## 98 0.9958506 0.0000000 Bacteria
## 99 0.9958506 0.0000000 Bacteria
## 100 0.9958506 0.0000000 Bacteria
## 101 1.0000000 1.0000000 Bacteria
## 102 1.0000000 1.0000000 Bacteria
## 103 1.0000000 1.0000000 Bacteria
## 104 1.0000000 1.0000000 Bacteria
## 105 1.0000000 1.0000000 Bacteria
## 106 1.0000000 1.0000000 Bacteria
## 107 1.0000000 1.0000000 Bacteria
## 108 1.0000000 1.0000000 Bacteria
## 109 1.0000000 1.0000000 Bacteria
## 110 1.0000000 1.0000000 Bacteria
## 111 1.0000000 1.0000000 Bacteria
## 112 1.0000000 1.0000000 Bacteria
## 113 1.0000000 1.0000000 Bacteria
## 114 1.0000000 1.0000000 Bacteria
## 115 1.0000000 1.0000000 Bacteria
## 116 1.0000000 1.0000000 Bacteria
## 117 1.0000000 1.0000000 Bacteria
## 118 1.0000000 1.0000000 Bacteria
## 119 1.0000000 1.0000000 Bacteria
## 120 1.0000000 1.0000000 Bacteria
## 121 1.0000000 1.0000000 Bacteria
## 122 1.0000000 1.0000000 Bacteria
## 123 1.0000000 1.0000000 Bacteria
## 124 1.0000000 1.0000000 Bacteria
## 125 1.0000000 1.0000000 Bacteria
## 126 1.0000000 1.0000000 Bacteria
## 127 1.0000000 1.0000000 Bacteria
## 128 1.0000000 1.0000000 Bacteria
## 129 1.0000000 1.0000000 Bacteria
## 130 1.0000000 1.0000000 Bacteria
## 131 1.0000000 1.0000000 Bacteria
## 132 1.0000000 1.0000000 Bacteria
## 133 1.0000000 1.0000000 Bacteria
## 134 1.0000000 1.0000000 Bacteria
## 135 1.0000000 1.0000000 Bacteria
## 136 1.0000000 1.0000000 Bacteria
## 137 0.9958506 0.0000000 Bacteria
## 138 1.0000000 1.0000000 Bacteria
## 139 1.0000000 1.0000000 Bacteria
## 140 1.0000000 1.0000000 Bacteria
## 141 1.0000000 1.0000000 Bacteria
## 142 1.0000000 1.0000000 Bacteria
## 143 1.0000000 1.0000000 Bacteria
## 144 1.0000000 1.0000000 Bacteria
## 145 1.0000000 1.0000000 Bacteria
## 146 1.0000000 1.0000000 Bacteria
## 147 1.0000000 1.0000000 Bacteria
## 148 1.0000000 1.0000000 Bacteria
## 149 1.0000000 1.0000000 Bacteria
## 150 1.0000000 1.0000000 Bacteria
## 151 1.0000000 1.0000000 Bacteria
## 152 1.0000000 1.0000000 Bacteria
## 153 1.0000000 1.0000000 Bacteria
## 154 1.0000000 1.0000000 Bacteria
## 155 1.0000000 1.0000000 Bacteria
## 156 1.0000000 1.0000000 Bacteria
## 157 1.0000000 1.0000000 Bacteria
## 158 1.0000000 1.0000000 Bacteria
## 159 1.0000000 1.0000000 Bacteria
## 160 1.0000000 1.0000000 Bacteria
## 161 1.0000000 1.0000000 Bacteria
## 162 1.0000000 1.0000000 Bacteria
## 163 1.0000000 1.0000000 Bacteria
## 164 1.0000000 1.0000000 Bacteria
## 165 1.0000000 1.0000000 Bacteria
## 166 1.0000000 1.0000000 Bacteria
## 167 1.0000000 1.0000000 Bacteria
## 168 1.0000000 1.0000000 Bacteria
## 169 1.0000000 1.0000000 Bacteria
## 170 1.0000000 1.0000000 Bacteria
## 171 1.0000000 1.0000000 Bacteria
## 172 1.0000000 1.0000000 Bacteria
## 173 1.0000000 1.0000000 Bacteria
## 174 1.0000000 1.0000000 Bacteria
## 175 1.0000000 1.0000000 Bacteria
## 176 1.0000000 1.0000000 Bacteria
## 177 1.0000000 1.0000000 Bacteria
## 178 1.0000000 1.0000000 Bacteria
## 179 1.0000000 1.0000000 Bacteria
## 180 1.0000000 1.0000000 Bacteria
## 181 1.0000000 1.0000000 Bacteria
## 182 1.0000000 1.0000000 Bacteria
## 183 1.0000000 1.0000000 Bacteria
## 184 1.0000000 1.0000000 Bacteria
## 185 1.0000000 1.0000000 Bacteria
## 186 1.0000000 1.0000000 Bacteria
## 187 1.0000000 1.0000000 Bacteria
## 188 1.0000000 1.0000000 Bacteria
## 189 1.0000000 1.0000000 Bacteria
## 190 1.0000000 1.0000000 Bacteria
## 191 1.0000000 1.0000000 Bacteria
## 192 1.0000000 1.0000000 Bacteria
## 193 1.0000000 1.0000000 Bacteria
## 194 1.0000000 1.0000000 Bacteria
## 195 1.0000000 1.0000000 Bacteria
## 196 1.0000000 1.0000000 Bacteria
## 197 1.0000000 1.0000000 Bacteria
## 198 1.0000000 1.0000000 Bacteria
## 199 1.0000000 1.0000000 Bacteria
## 200 1.0000000 1.0000000 Bacteria
## 201 1.0000000 1.0000000 Bacteria
## 202 1.0000000 1.0000000 Bacteria
## 203 1.0000000 1.0000000 Bacteria
## [ reached 'max' / getOption("max.print") -- omitted 207797 rows ]